Mario Gerges
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View article: The triglyceride-glucose index as a predictor of cardiovascular abnormalities in obese patients
The triglyceride-glucose index as a predictor of cardiovascular abnormalities in obese patients Open
Background Obesity is increasingly regarded as a chronic disease and has contributed significantly to the growth of chronic, non-communicable diseases worldwide, especially cardiovascular disease. Early identification of cardiovascular ris…
View article: Role of thyroid antibodies in the diagnosis of thyroid eye disease
Role of thyroid antibodies in the diagnosis of thyroid eye disease Open
Background Thyroid eye disease (TED) is an autoimmune disorder caused by autoantibodies targeting thyroid-stimulating hormone (TSH) receptors. Aim To correlate the clinical profile of TED with the level of circulating biomarkers [TSH recep…
View article: Left Ventricular Filling Pressure in Chronic Thromboembolic Pulmonary Hypertension
Left Ventricular Filling Pressure in Chronic Thromboembolic Pulmonary Hypertension Open
Elevated LVFP is common, appears to be due to comorbid left heart disease, and predicts prognosis in CTEPH.
View article: Supplementary Material for: Report on a Case with Moreno-Nishimura-Schmidt Overgrowth Syndrome: A Clinically Delineated Disease Yet of an Unknown Origin!
Supplementary Material for: Report on a Case with Moreno-Nishimura-Schmidt Overgrowth Syndrome: A Clinically Delineated Disease Yet of an Unknown Origin! Open
Introduction: Overgrowth syndromes are a heterogeneous group of genetic disorders characterized by excessive growth, often accompanied by additional clinical features, such as facial dysmorphism, hormonal imbalances, cognitive impairment, …
View article: Efficacy and Safety of Percutaneous Pulmonary Artery Subtotal Occlusion and Chronic Total Occlusion Intervention in Chronic Thromboembolic Pulmonary Hypertension
Efficacy and Safety of Percutaneous Pulmonary Artery Subtotal Occlusion and Chronic Total Occlusion Intervention in Chronic Thromboembolic Pulmonary Hypertension Open
Background: Balloon pulmonary angioplasty (BPA) is an emerging percutaneous therapy for patients with inoperable chronic thromboembolic pulmonary hypertension, and patients with mean pulmonary artery pressure ≤30 mm Hg have an excellent su…
View article: Chronic thromboembolic pulmonary hypertension – still evolving
Chronic thromboembolic pulmonary hypertension – still evolving Open
Chronic thromboembolic pulmonary hypertension (CTEPH) is one of the leading causes of severe pulmonary hypertension (PH). The disease is still underdiagnosed, and the true prevalence is unknown. CTEPH is characterized by intraluminal non-r…
View article: Pulmonary artery to ascending aorta ratio by echocardiography: A strong predictor for presence and severity of pulmonary hypertension
Pulmonary artery to ascending aorta ratio by echocardiography: A strong predictor for presence and severity of pulmonary hypertension Open
The PA can be visualized in almost all echocardiographic exams, especially when it is dilated. A view showing the pulmonary trunk should be included in every routine TTE. An increased PA:A should raise suspicion for PH and prompt further e…
View article: Microvascular Disease in Chronic Thromboembolic Pulmonary Hypertension
Microvascular Disease in Chronic Thromboembolic Pulmonary Hypertension Open
Background: Pulmonary endarterectomy (PEA) is the gold standard treatment for patients with operable chronic thromboembolic pulmonary hypertension. However, persistent pulmonary hypertension (PH) after PEA remains a major determinant of po…
View article: In-depth haemodynamic phenotyping of pulmonary hypertension due to left heart disease
In-depth haemodynamic phenotyping of pulmonary hypertension due to left heart disease Open
The commonest cause of pulmonary hypertension (PH) is left heart disease (LHD). The current classification system for definitions of PH-LHD is under review. We therefore performed prospective in-depth invasive haemodynamic phenotyping in o…
View article: Subcutaneous treprostinil in congenital heart disease-related pulmonary arterial hypertension
Subcutaneous treprostinil in congenital heart disease-related pulmonary arterial hypertension Open
Objective To assess the efficacy and safety of subcutaneous treprostinil in adult patients with congenital heart disease (CHD)-associated pulmonary arterial hypertension (PAH) after 12 months of treatment. Methods Consecutive adult patient…
View article: Hemodynamic Phenotyping of Pulmonary Hypertension in Left Heart Failure
Hemodynamic Phenotyping of Pulmonary Hypertension in Left Heart Failure Open
Increased pulmonary venous pressure secondary to left heart disease is the most common cause of pulmonary hypertension (PH). The diagnosis of PH due to left heart disease relies on a clinical probability assessment followed by the invasive…
View article: P5367Chronic inflammation after splenectomy is a risk factor for increased thrombotic cardiovascular events
P5367Chronic inflammation after splenectomy is a risk factor for increased thrombotic cardiovascular events Open
did not received exercise intervention.Mitochondrial functionality and dynamic TG of platelets under hypoxic exercise (HE, 100W under 12%O2 for 30 min) were determined before and after the various interventions.Before the intervention, HE …
View article: Hemodynamic Thresholds for Precapillary Pulmonary Hypertension
Hemodynamic Thresholds for Precapillary Pulmonary Hypertension Open
mPAWP < 12 mm Hg and DPG > 20 mm Hg identify patients with PAH who are likely to have significant hemodynamic improvement with prostacyclin treatment.
View article: Advanced Imaging Tools Rather Than Hemodynamics Should Be the Primary Approach for Diagnosing, Following, and Managing Pulmonary Arterial Hypertension
Advanced Imaging Tools Rather Than Hemodynamics Should Be the Primary Approach for Diagnosing, Following, and Managing Pulmonary Arterial Hypertension Open
Pulmonary hypertension (PH) is currently defined based on invasive measurements: a resting pulmonary artery pressure ≥ 25 mm Hg. For pulmonary arterial hypertension, a pulmonary arterial wedge pressure ≤ 15 mm Hg and pulmonary vascular res…