Michaela E. Dungan
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View article: Gastric epithelium from <i>BRCA1</i> and <i>BRCA2</i> carriers harbors increased double-stranded DNA damage and augmented growth
Gastric epithelium from <i>BRCA1</i> and <i>BRCA2</i> carriers harbors increased double-stranded DNA damage and augmented growth Open
An accumulating body of evidence suggests carriers of a pathogenic germline variant (PGV) in BRCA1 or BRCA2 have increased gastric cancer (GC) risk. BRCA1 and BRCA2 are tumor suppressor genes involved in promoting homologous recombination …
View article: Colorectal Neoplasia Detection Rates in Lynch Syndrome
Colorectal Neoplasia Detection Rates in Lynch Syndrome Open
Background: The expected and optimal adenoma detection rate (ADR) is not well characterized in Lynch syndrome (LS). The aim of this study is to determine the ADR, the overall colorectal neoplasia detection rate (CNDR), proximal serrated de…
View article: Prevalence of <i>H. pylori</i> and Gastric Intestinal Metaplasia in <i>BRCA1</i> and <i>BRCA2</i> Carriers
Prevalence of <i>H. pylori</i> and Gastric Intestinal Metaplasia in <i>BRCA1</i> and <i>BRCA2</i> Carriers Open
BRCA1 and BRCA2 carriers may be at increased risk for gastric cancer; however, the mechanisms of gastric carcinogenesis remain poorly understood. We sought to determine the prevalence of gastric cancer risk factors Helicobacter pylori (H. …
View article: Assessment of the Psychosocial Impact of Pancreatic Cancer Surveillance in High-Risk Individuals
Assessment of the Psychosocial Impact of Pancreatic Cancer Surveillance in High-Risk Individuals Open
Objectives: Pancreatic cancer (PC) surveillance of high-risk individuals (HRIs) downstages PC and improves survival. However, it remains less clear whether PC surveillance has a positive psychosocial impact on HRIs. Herein, we aimed to def…