Michal Frelich
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View article: Effect of second-hand smoking on the incidence of postoperative nausea and vomiting in children after adenoidectomy: a single-centre retrospective study
Effect of second-hand smoking on the incidence of postoperative nausea and vomiting in children after adenoidectomy: a single-centre retrospective study Open
Although exposure to ETS has many undesirable consequences, it is also associated with a lower incidence of PONV. Conversely, children without ETS exposure are at a higher risk of PONV development and should receive proactive pharmacologic…
View article: Protective mechanical ventilation controlled by the real-time mechanical power measurement
Protective mechanical ventilation controlled by the real-time mechanical power measurement Open
ClinicalTrials NCT06035146.
View article: Protective mechanical ventilation controlled by the real-time mechanical energy measurement
Protective mechanical ventilation controlled by the real-time mechanical energy measurement Open
Background Despite the substantial advancements in mechanical ventilation (MV), mortality remains high. Mechanical energy (ME), MV forces are associated with outcomes. Real-time monitoring of ME and the adjustment of MV according to ME may…
View article: ECMO as salvage therapy for neutropenic enterocolitis with refractory septic shock and abdominal compartment syndrome in a patient with acute lymphoblastic leukemia
ECMO as salvage therapy for neutropenic enterocolitis with refractory septic shock and abdominal compartment syndrome in a patient with acute lymphoblastic leukemia Open
View article: Lessons Learned From Awake ECMO Approach in Covid-19-Related Acute Respiratory Distress Syndrome - a Scoping Review
Lessons Learned From Awake ECMO Approach in Covid-19-Related Acute Respiratory Distress Syndrome - a Scoping Review Open
During the COVID-19 pandemic, specific COVID-19-related conditions renewed interest in the full-awake venovenous extracorporeal membrane oxygenation ( fa V-V ECMO) approach, in which ECMO is applied to awake, cooperative,…
View article: Activated Partial Thromboplastin Time and Anti-IIa Monitoring in Argatroban Anticoagulation in COVID-19 Patients on Venovenous Extracorporeal Membrane Oxygenation
Activated Partial Thromboplastin Time and Anti-IIa Monitoring in Argatroban Anticoagulation in COVID-19 Patients on Venovenous Extracorporeal Membrane Oxygenation Open
Unfractionated heparin has long been considered the standard anticoagulation in ECMO, despite some pitfalls such as heparin resistance, heparin induced thrombocytopenia (HIT), etc Recently, some centres started to increasingly use argatrob…
View article: HMGB-1 as a predictor of major bleeding requiring activation of a massive transfusion protocol in severe trauma
HMGB-1 as a predictor of major bleeding requiring activation of a massive transfusion protocol in severe trauma Open
Massive bleeding causes approximately 50% of deaths in patients with major trauma. Most patients die within 6 h of injury, which is preventable in at least 10% of cases. For these patients, early activation of the massive transfusion proto…
View article: Emergence delirium in children: up to date for pediatricians
Emergence delirium in children: up to date for pediatricians Open
View article: HMGB-1 as a predictor of major bleeding requiring activation of a massive transfusion protocol in severe trauma
HMGB-1 as a predictor of major bleeding requiring activation of a massive transfusion protocol in severe trauma Open
Background Massive bleeding causes approximately 50% of deaths in patients with major trauma. Most patients die within 6 hours of injury, which is preventable in at least 10% of cases. For these patients, early activation of the massive tr…
View article: A safety comparison of heparin and argatroban anticoagulation in veno‐venous extracorporeal membrane oxygenation with a focus on bleeding
A safety comparison of heparin and argatroban anticoagulation in veno‐venous extracorporeal membrane oxygenation with a focus on bleeding Open
Background Anticoagulation during extracorporeal membrane oxygenation (ECMO) might still lead to severe bleeding complications. Heparin is the most frequently used anticoagulant, but novel drugs could be promising. Argatroban is a new alte…
View article: HMGB-1 as a predictor of massive transfusion protocol activation in major trauma: a prospective observational study
HMGB-1 as a predictor of massive transfusion protocol activation in major trauma: a prospective observational study Open
Background Massive bleeding causes approximately 50% of deaths in patients with major trauma. Most patients die within 6 hours of injury, which is preventable in at least 10% of cases. For these patients, early activation of the massive tr…
View article: The effect of BIS-guided anaesthesia on the incidence of postoperative nausea and vomiting in children: a prospective randomized double-blind study
The effect of BIS-guided anaesthesia on the incidence of postoperative nausea and vomiting in children: a prospective randomized double-blind study Open
View article: A Safety Comparison of Heparin and Argatroban Anticoagulation in Veno-Venous Extracorporeal Membrane Oxygenation with a Focus on Bleeding
A Safety Comparison of Heparin and Argatroban Anticoagulation in Veno-Venous Extracorporeal Membrane Oxygenation with a Focus on Bleeding Open
View article: Predicting Acute Kidney Injury in Trauma Patients: Biomarkers as Early Indicators
Predicting Acute Kidney Injury in Trauma Patients: Biomarkers as Early Indicators Open
BACKGROUND Acute kidney injury (AKI) is a common cause of organ failure in patients after major trauma and is associated with increased morbidity and mortality. Early identification of patients at risk enables the implementation of a bundl…
View article: Effect of BIS-guided anesthesia on emergence delirium following general anesthesia in children: A prospective randomized controlled trial
Effect of BIS-guided anesthesia on emergence delirium following general anesthesia in children: A prospective randomized controlled trial Open
NCT04466579.
View article: Long-Term Outcomes of Extracorporeal Life Support in Respiratory Failure
Long-Term Outcomes of Extracorporeal Life Support in Respiratory Failure Open
Although extracorporeal life support is an expensive method with serious risks of complications, it is nowadays a well-established and generally accepted method of organ support. In patients with severe respiratory failure, when convention…
View article: The Impact of Mechanical Energy Assessment on Mechanical Ventilation: A Comprehensive Review and Practical Application
The Impact of Mechanical Energy Assessment on Mechanical Ventilation: A Comprehensive Review and Practical Application Open
Mechanical ventilation (MV) provides basic organ support for patients who have acute hypoxemic respiratory failure, with acute respiratory distress syndrome as the most severe form. The use of excessive ventilation forces can exacerbate th…
View article: Postdischarge nausea and vomiting (PDNV) in children: A review and observational study
Postdischarge nausea and vomiting (PDNV) in children: A review and observational study Open
Postdischarge nausea and vomiting (PDNV) cause substantial pediatric morbidity with potentially serious postoperative complications. However, few studies have addressed PDNV prevention and treatment in pediatric patients. Here we searched …
View article: Patient Self-Inflicted Lung Injury—A Narrative Review of Pathophysiology, Early Recognition, and Management Options
Patient Self-Inflicted Lung Injury—A Narrative Review of Pathophysiology, Early Recognition, and Management Options Open
Patient self-inflicted lung injury (P-SILI) is a life-threatening condition arising from excessive respiratory effort and work of breathing in patients with lung injury. The pathophysiology of P-SILI involves factors related to the underly…
View article: Comments on Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021 - What to Do in the Initial Hours?
Comments on Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021 - What to Do in the Initial Hours? Open
View article: Anticoagulation Management during Extracorporeal Membrane Oxygenation—A Mini-Review
Anticoagulation Management during Extracorporeal Membrane Oxygenation—A Mini-Review Open
Extracorporeal membrane oxygenation (ECMO) has been established as a life-saving technique for patients with the most severe forms of respiratory or cardiac failure. It can, however, be associated with severe complications. Anticoagulation…
View article: Neonates undergoing pyloric stenosis repair are at increased risk of difficult airway management: secondary analysis of the NEonate and Children audiT of Anaesthesia pRactice IN Europe
Neonates undergoing pyloric stenosis repair are at increased risk of difficult airway management: secondary analysis of the NEonate and Children audiT of Anaesthesia pRactice IN Europe Open
View article: Postoperative nausea and vomiting
Postoperative nausea and vomiting Open
II. klinika anesteziológie a intenzívnej medicíny Slovenskej zdravotníckej univerzity FNsP F
View article: Possibilities of the anesthesiologist to influence the clarity of the operating field in endonasal surgery
Possibilities of the anesthesiologist to influence the clarity of the operating field in endonasal surgery Open
EndoskopickĂĄ endonazĂĄlnĂ chirurgie se zabĂ˝vĂĄ operacemi nosu a paranazĂĄlnĂch dutin. Nos a paranazĂĄlnĂ dutiny jsou bohatÄ cĂŠvnÄ zĂĄsobenĂŠ, slizniÄnĂ krvĂĄcenĂ je proto ÄastĂŠ a vĂ˝raznÄ zhorĹĄuje pĹehlednost operaÄnĂho p…
View article: Corrigendum to ‘Difficult tracheal intubation in neonates and infants. NEonate and Children audiT of Anaesthesia pRactice IN Europe (NECTARINE): a prospective European multicentre observational study’ (Br J Anaesth 2021; 126: 1173–81)
Corrigendum to ‘Difficult tracheal intubation in neonates and infants. NEonate and Children audiT of Anaesthesia pRactice IN Europe (NECTARINE): a prospective European multicentre observational study’ (Br J Anaesth 2021; 126: 1173–81) Open
View article: Morbidity and mortality after anaesthesia in early life: results of the European prospective multicentre observational study, neonate and children audit of anaesthesia practice in Europe (NECTARINE)
Morbidity and mortality after anaesthesia in early life: results of the European prospective multicentre observational study, neonate and children audit of anaesthesia practice in Europe (NECTARINE) Open
View article: Difficult tracheal intubation in neonates and infants. NEonate and Children audiT of Anaesthesia pRactice IN Europe (NECTARINE): a prospective European multicentre observational study
Difficult tracheal intubation in neonates and infants. NEonate and Children audiT of Anaesthesia pRactice IN Europe (NECTARINE): a prospective European multicentre observational study Open
View article: Dexamethasone Reduces the Incidence of Postoperative Nausea and Vomiting in Children Undergoing Endoscopic Adenoidectomy under General Anesthesia Without Increasing the Risk of Postoperative Hemorrhage
Dexamethasone Reduces the Incidence of Postoperative Nausea and Vomiting in Children Undergoing Endoscopic Adenoidectomy under General Anesthesia Without Increasing the Risk of Postoperative Hemorrhage Open
BACKGROUND Postoperative nausea and vomiting (PONV) is a common complication of pediatric anesthesia, but the overall incidence of PONV in patients undergoing adenoidectomy is unknown. The aim of this controlled study was to compare the ef…
View article: Incidence of severe critical events in paediatric anaesthesia (APRICOT): a prospective multicentre observational study in 261 hospitals in Europe
Incidence of severe critical events in paediatric anaesthesia (APRICOT): a prospective multicentre observational study in 261 hospitals in Europe Open