Michal Jarník YOU? Author Swipe

Last 10y

Non-synaptic Mechanism of Ocular Dominance Plasticity Open

Michael B. Foote, William Huffman, Erin Santos, Philip R. Lee, Michal Jarník , et al. · 2025

Classic experiments showing that monocular visual disruption alters synaptic connections to binocular neurons in the brain established the fundamental concept of synaptic plasticity through coincident spike time arrival. However, if the sp…

Liver-specific loss of <i>Atg9a</i> perturbs lipid metabolism and hepatocyte integrity Open

Élodie Mailler, Asmita Singh, Michal Jarník, Yan Li, Lynne A. Holtzclaw , et al. · 2025

The autophagy-related protein ATG9A is integral to cellular autophagy and lipid mobilization, yet its importance in mammalian physiology remains underexplored. Using a liver-specific conditional Atg9a knockout (Atg9a-cKO) mou…

CHIP protects lysosomes from CLN4 mutant-induced membrane damages Open

Juhyung Lee, Jizhong Zou, Wan Nur Atiqah Binti Mazli, N.Y. Chin, Michal Jarník , et al. · 2025

Understanding how cells mitigate lysosomal damage is critical for unraveling pathogenic mechanisms of lysosome-related diseases. Here we use organelle-specific proteomics in iPSC-derived neurons (i 3 Neuron) and an in vitro lysosome-damagi…

Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration Open

Raffaella De Pace, Saikat Ghosh, Veronica H. Ryan, Mira Sohn, Michal Jarník , et al. · 2024

The Legionella pneumophila effector DenR hijacks the host NRas proto-oncoprotein to downregulate MAPK signaling Open

Stephanie S. Lehman, Chad D. Williamson, Trisha Tucholski, Nicole A. Ellis, Sabrina Bouchard , et al. · 2024

Author Response: σ28-dependent small RNA regulation of flagella biosynthesis Open

Sahar Melamed, Aixia Zhang, Michal Jarník, Joshua Mills, Aviezer Silverman , et al. · 2023

Full text Figures and data Side by side Abstract eLife assessment Introduction Results Discussion Materials and methods Data availability References Peer review Author response Article and author information Abstract Flagella are important…

σ28-dependent small RNA regulation of flagella biosynthesis Open

Sahar Melamed, Aixia Zhang, Michal Jarník, Joshua Mills, Aviezer Silverman , et al. · 2023

Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive transcriptional regulation has been described, little is known about the posttranscriptional …

Reviewer #1 (Public Review): σ28-dependent small RNA regulation of flagella biosynthesis Open

Sahar Melamed, Aixia Zhang, Michal Jarník, Joshua Mills, Aviezer Silverman , et al. · 2023

Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive transcriptional regulation has been described, little is known about the posttranscriptional …

σ28-dependent small RNA regulation of flagella biosynthesis Open

Sahar Melamed, Aixia Zhang, Michal Jarník, Joshua Mills, Aviezer Silverman , et al. · 2023

Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive transcriptional regulation has been described, little is known about the posttranscriptional …

Author Response: σ28-dependent small RNA regulation of flagella biosynthesis Open

Sahar Melamed, Aixia Zhang, Michal Jarník, Joshua Mills, Aviezer Silverman , et al. · 2023

Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive transcriptional regulation has been described, little is known about the posttranscriptional …

Reviewer #3 (Public Review): σ28-dependent small RNA regulation of flagella biosynthesis Open

Sahar Melamed, Aixia Zhang, Michal Jarník, Joshua Mills, Aviezer Silverman , et al. · 2023

Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive transcriptional regulation has been described, little is known about the posttranscriptional …

Reviewer #2 (Public Review): σ28-dependent small RNA regulation of flagella biosynthesis Open

Sahar Melamed, Aixia Zhang, Michal Jarník, Joshua Mills, Aviezer Silverman , et al. · 2023

Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive transcriptional regulation has been described, little is known about the posttranscriptional …

σ28-dependent small RNA regulation of flagella biosynthesis Open

Sahar Melamed, Aixia Zhang, Michal Jarník, Joshua Mills, Aviezer Silverman , et al. · 2023

Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive transcriptional regulation has been described, little is known about the posttranscriptional …

Reviewer #1 (Public Review): σ28-dependent small RNA regulation of flagella biosynthesis Open

Sahar Melamed, Aixia Zhang, Michal Jarník, Joshua Mills, Aviezer Silverman , et al. · 2023

Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive transcriptional regulation has been described, little is known about the posttranscriptional …

σ28-dependent small RNA regulation of flagella biosynthesis Open

Sahar Melamed, Aixia Zhang, Michal Jarník, Joshua Mills, Aviezer Silverman , et al. · 2023

Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive transcriptional regulation has been described, little is known about the posttranscriptional …

Author Response: σ28-dependent small RNA regulation of flagella biosynthesis Open

Sahar Melamed, Aixia Zhang, Michal Jarník, Joshua Mills, Aviezer Silverman , et al. · 2023

Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive transcriptional regulation has been described, little is known about the posttranscriptional …

Inhibition of endolysosome fusion increases exosome secretion Open

Ganesh Vilas Shelke, Chad D. Williamson, Michal Jarník, Juan S. Bonifacino · 2023

Exosomes are small vesicles that are secreted from cells to dispose of undegraded materials and mediate intercellular communication. A major source of exosomes is intraluminal vesicles within multivesicular endosomes that undergo exocytic …

Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling Open

Xuesong Feng, A. Hongjun Wang, Aster H. Juan, Kyung Dae Ko, Kan Jiang , et al. · 2023

Supplementary Figure 1 from The ARF Tumor Suppressor Can Promote the Progression of Some Tumors Open

Olivier Humbey, Julia Pimkina, Jack T. Zilfou, Michal Jarník, Carmen Dominguez‐Brauer , et al. · 2023

Supplementary Figure 1 from The ARF Tumor Suppressor Can Promote the Progression of Some Tumors

Supplementary Figure 2 from The ARF Tumor Suppressor Can Promote the Progression of Some Tumors Open

Olivier Humbey, Julia Pimkina, Jack T. Zilfou, Michal Jarník, Carmen Dominguez‐Brauer , et al. · 2023

Supplementary Figure 2 from The ARF Tumor Suppressor Can Promote the Progression of Some Tumors

Supplementary Figure 2 from The ARF Tumor Suppressor Can Promote the Progression of Some Tumors Open

Olivier Humbey, Julia Pimkina, Jack T. Zilfou, Michal Jarník, Carmen Dominguez‐Brauer , et al. · 2023

Supplementary Figure 2 from The ARF Tumor Suppressor Can Promote the Progression of Some Tumors

Supplementary Figure Legends 1-2 from The ARF Tumor Suppressor Can Promote the Progression of Some Tumors Open

Olivier Humbey, Julia Pimkina, Jack T. Zilfou, Michal Jarník, Carmen Dominguez‐Brauer , et al. · 2023

Supplementary Figure Legends 1-2 from The ARF Tumor Suppressor Can Promote the Progression of Some Tumors

Data from The ARF Tumor Suppressor Can Promote the Progression of Some Tumors Open

Olivier Humbey, Julia Pimkina, Jack T. Zilfou, Michal Jarník, Carmen Dominguez‐Brauer , et al. · 2023

p14/p19^ARF (ARF) is a tumor suppressor gene that is frequently mutated in human cancer. ARF has multiple tumor suppressor functions, some of which are mediated by signaling to p53. Surprisingly, a significant fract…

Supplementary Figure Legends 1-2 from The ARF Tumor Suppressor Can Promote the Progression of Some Tumors Open

Olivier Humbey, Julia Pimkina, Jack T. Zilfou, Michal Jarník, Carmen Dominguez‐Brauer , et al. · 2023

Supplementary Figure Legends 1-2 from The ARF Tumor Suppressor Can Promote the Progression of Some Tumors

Supplementary Figure 1 from The ARF Tumor Suppressor Can Promote the Progression of Some Tumors Open

Olivier Humbey, Julia Pimkina, Jack T. Zilfou, Michal Jarník, Carmen Dominguez‐Brauer , et al. · 2023

Supplementary Figure 1 from The ARF Tumor Suppressor Can Promote the Progression of Some Tumors

Data from The ARF Tumor Suppressor Can Promote the Progression of Some Tumors Open

Olivier Humbey, Julia Pimkina, Jack T. Zilfou, Michal Jarník, Carmen Dominguez‐Brauer , et al. · 2023

p14/p19^ARF (ARF) is a tumor suppressor gene that is frequently mutated in human cancer. ARF has multiple tumor suppressor functions, some of which are mediated by signaling to p53. Surprisingly, a significant fract…

The <i>Legionella pneumophila</i> Effector DenR Hijacks the Host NRas Proto-Oncoprotein to Downregulate MAPK Signaling Open

Stephanie S. Lehman, Chad D. Williamson, Trisha Tucholski, Nicole A. Ellis, Sabrina Bouchard , et al. · 2023

VpdC is a ubiquitin-activated phospholipase effector that regulates <i>Legionella</i> vacuole expansion during infection Open

Xiao Li, David E. Anderson, Yuen‐Yan Chang, Michal Jarník, Matthias P. Machner · 2022

Intravacuolar pathogens need to gradually expand their surrounding vacuole to accommodate the growing number of bacterial offspring during intracellular replication. Here we found that Legionella pneumophila controls vacuole expansion by f…

The autophagy protein ATG9A enables lipid mobilization from lipid droplets Open

Élodie Mailler, Carlos M. Guardia, Xiaofei Bai, Michal Jarník, Chad D. Williamson , et al. · 2021

σ <sup>28</sup> -dependent small RNA regulation of flagella biosynthesis Open

Sahar Melamed, Aixia Zhang, Michal Jarník, Joshua Mills, Aviezer Silverman , et al. · 2021

Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive transcriptional regulation has been described, little is known about the posttranscriptional …

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