Michal Vojtíšek-Lom
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View article: From real-driving emissions to urban air quality: composition of aged PM from modern diesel, gasoline, and CNG fueled cars and plug-in hybrid electric vehicles
From real-driving emissions to urban air quality: composition of aged PM from modern diesel, gasoline, and CNG fueled cars and plug-in hybrid electric vehicles Open
Secondary aerosol emissions from vehicle exhaust often surpass primary particle emissions, yet they are not currently regulated, as they remain difficult to constrain. Here we investigate the factors driving the formation and chemical comp…
View article: Identification of high emitting heavy duty vehicles using Plume Chasing: European case study for enforcement
Identification of high emitting heavy duty vehicles using Plume Chasing: European case study for enforcement Open
The real-world emissions of almost 5000 heavy-duty vehicles (HDVs), determined by the Plume Chasing method in different European countries from 2016 to 2023, are presented. NOx emission factors are provided for all assessed vehi…
View article: In-situ investigation of real-world emissions from 111 measurements on solid fuel household boilers
In-situ investigation of real-world emissions from 111 measurements on solid fuel household boilers Open
Over the years, emissions from significant stationary and mobile sources have significantly reduced, while solid fuel household combustion appliances have substantially contributed to air pollution. Growing evidence links residential solid…
View article: Importance of sub-23 nm particles in traffic environments: Particle number emission factors and extrathoracic deposition doses
Importance of sub-23 nm particles in traffic environments: Particle number emission factors and extrathoracic deposition doses Open
New research suggests that exposure to ultrafine particles (UFPs; particle diameter dp < 100 nm) is particularly harmful to brain health. One pathway into the body is via deposition in the respiratory system, where the smallest …
View article: From Real-Driving Emissions to Urban Air Quality: Composition of Aged Pm from Modern Diesel, Gasoline, and Cng Fueled Cars and Plug-In Hybrid Electric Vehicles
From Real-Driving Emissions to Urban Air Quality: Composition of Aged Pm from Modern Diesel, Gasoline, and Cng Fueled Cars and Plug-In Hybrid Electric Vehicles Open
View article: Portable emissions toxicity system: Evaluating the toxicity of emissions or polluted air by exposure of cell cultures at air-liquid interface in a compact field-deployable setup
Portable emissions toxicity system: Evaluating the toxicity of emissions or polluted air by exposure of cell cultures at air-liquid interface in a compact field-deployable setup Open
Exposure of cell cultures at air-liquid interface (ALI), mimicking i.e. human lung surface, is believed to be one of the most realistic means to model toxicity of complex mixtures of pollutants on human health. The complexity of the close …
View article: Practical, low-cost integrity testing of diesel particle filters using remote sensing measurement at the campus entrance gate
Practical, low-cost integrity testing of diesel particle filters using remote sensing measurement at the campus entrance gate Open
This work investigates the detection of defunct or absent diesel particle filters by drive-through remote sensing measurement at the Czech University of Life Sciences main vehicular entrance gate. An exhaust sample was collected by a line …
View article: Real-world outdoor air exposure effects in a model of the human airway epithelium – A comparison of healthy and asthmatic individuals using a mobile laboratory setting
Real-world outdoor air exposure effects in a model of the human airway epithelium – A comparison of healthy and asthmatic individuals using a mobile laboratory setting Open
We developed a mobile laboratory allowing field exposure of lung tissue models to ambient air at localities with various pollution sources (Background, Industrial, Traffic, Urban) in different seasons (summer/fall/winter). In samples origi…
View article: Transcriptomic and epigenomic profiling reveals altered responses to diesel emissions in Alzheimer's disease both in vitro and in population‐based data
Transcriptomic and epigenomic profiling reveals altered responses to diesel emissions in Alzheimer's disease both in vitro and in population‐based data Open
INTRODUCTION Studies have correlated living close to major roads with Alzheimer's disease (AD) risk. However, the mechanisms responsible for this link remain unclear. METHODS We exposed olfactory mucosa (OM) cells of healthy individuals an…
View article: Review of: "[Commentary] On Heated Tobacco Products and the Importance of Science-Based Assessments and Product Classification"
Review of: "[Commentary] On Heated Tobacco Products and the Importance of Science-Based Assessments and Product Classification" Open
Potential competing interests: No potential competing interests to
View article: Portable Emissions Toxicity System: Evaluating the Toxicity of Emissions or Polluted Air by Exposure of Cell Cultures at Air-Liquid Interface in a Compact Field-Deployable Setup
Portable Emissions Toxicity System: Evaluating the Toxicity of Emissions or Polluted Air by Exposure of Cell Cultures at Air-Liquid Interface in a Compact Field-Deployable Setup Open
View article: Practical, Low-Cost Integrity Testing of Diesel Particle Filters Using Remote Sensing Measurement at the Campus Entrance Gate
Practical, Low-Cost Integrity Testing of Diesel Particle Filters Using Remote Sensing Measurement at the Campus Entrance Gate Open
View article: The Genotoxicity of Organic Extracts from Particulate Emissions Produced by Neat Gasoline (E0) and a Gasoline–Ethanol Blend (E15) in BEAS-2B Cells
The Genotoxicity of Organic Extracts from Particulate Emissions Produced by Neat Gasoline (E0) and a Gasoline–Ethanol Blend (E15) in BEAS-2B Cells Open
Emissions from modern gasoline engines represent an environmental and health risk. In this study, we aimed to compare the toxicity of organic compound mixtures extracted from particulate matter (PM extracts) produced by neat gasoline (E0) …
View article: Lung-depositing surface area (LDSA) of particles in office spaces around Europe: Size distributions, I/O-ratios and infiltration
Lung-depositing surface area (LDSA) of particles in office spaces around Europe: Size distributions, I/O-ratios and infiltration Open
Air pollution, and specifically particulate matter pollution, is one of the greatest dangers to human health. Outdoor air pollution ranks third in causes for premature death. Improving indoor air quality is of immense importance, as the ti…
View article: Particle lung deposited surface area (LDSAal) size distributions in different urban environments and geographical regions: Towards understanding of the PM2.5 dose–response
Particle lung deposited surface area (LDSAal) size distributions in different urban environments and geographical regions: Towards understanding of the PM2.5 dose–response Open
Recent studies indicate that monitoring only fine particulate matter (PM2.5) may not be enough to understand and tackle the health risk caused by particulate pollution. Health effects per unit PM2.5 seem to increase i…
View article: Lung-Depositing Particles in Office Spaces Around Europe
Lung-Depositing Particles in Office Spaces Around Europe Open
View article: Regulated and unregulated emissions and exhaust flow measurement of four in-use high performance motorcycles
Regulated and unregulated emissions and exhaust flow measurement of four in-use high performance motorcycles Open
Exhaust emissions from four larger motorcycles, 599–1078 cm3 engine displacement, 2008 to 2015 model years, were measured on a chassis dynamometer using cold and hot engine start World Motorcycle Transient Cycle. Raw exhaust gas was sample…
View article: The impact of extractable organic matter from gasoline and alternative fuel emissions on bronchial cell models (BEAS-2B, MucilAir™)
The impact of extractable organic matter from gasoline and alternative fuel emissions on bronchial cell models (BEAS-2B, MucilAir™) Open
Air pollution caused by road traffic has an unfavorable impact on the environment and also on human health. It has previously been shown, that complete gasoline emissions lead to toxic effects in cell models originating from human airways.…
View article: Transcription profiles in BEAS-2B cells exposed to organic extracts from particulate emissions produced by a port-fuel injection vehicle, fueled with conventional fossil gasoline and gasoline-ethanol blend
Transcription profiles in BEAS-2B cells exposed to organic extracts from particulate emissions produced by a port-fuel injection vehicle, fueled with conventional fossil gasoline and gasoline-ethanol blend Open
Emissions from road traffic are among the major contributors to air pollution worldwide and represent a serious environmental health risk. Although traffic-related pollution has been most commonly associated with diesel engines, increasing…
View article: In vitro exposure to complete engine emissions – a mini-review
In vitro exposure to complete engine emissions – a mini-review Open
Outdoor air pollution is classified as carcinogenic to humans and exposure to it contributes to increased incidence of various diseases, including cardiovascular, neurological or pulmonary disorders. Vehicle engine emissions represent a si…
View article: High NO2 Concentrations Measured by Passive Samplers in Czech Cities: Unresolved Aftermath of Dieselgate?
High NO2 Concentrations Measured by Passive Samplers in Czech Cities: Unresolved Aftermath of Dieselgate? Open
This work examines the effects of two problematic trends in diesel passenger car emissions—increasing NO2/NOx ratio by conversion of NO into NO2 in catalysts and a disparity between the emission limit and the actual emissions in everyday d…
View article: Markers of lipid oxidation and inflammation in bronchial cells exposed to complete gasoline emissions and their organic extracts
Markers of lipid oxidation and inflammation in bronchial cells exposed to complete gasoline emissions and their organic extracts Open
Road traffic emissions consist of gaseous components, particles of various sizes, and chemical compounds that are bound to them. Exposure to vehicle emissions is implicated in the etiology of inflammatory respiratory disorders. We investig…
View article: High NO2 cOncentrations Measured by Passive Samplers in Czech Cities: Unresolved Aftermath of Dieselgate?
High NO2 cOncentrations Measured by Passive Samplers in Czech Cities: Unresolved Aftermath of Dieselgate? Open
This work examines the effects of two problematic trends in diesel passenger car emissions – increasing NO2/NOx ratio by conversion of NO into NO2 in catalysts and a disparity between the emission limit and the actual emissions in ev…
View article: Ordinary Gasoline Emissions Induce a Toxic Response in Bronchial Cells Grown at Air-Liquid Interface
Ordinary Gasoline Emissions Induce a Toxic Response in Bronchial Cells Grown at Air-Liquid Interface Open
Gasoline engine emissions have been classified as possibly carcinogenic to humans and represent a significant health risk. In this study, we used MucilAir™, a three-dimensional (3D) model of the human airway, and BEAS-2B, cells originating…
View article: A miniature Portable Emissions Measurement System (PEMS) for real-driving monitoring of motorcycles
A miniature Portable Emissions Measurement System (PEMS) for real-driving monitoring of motorcycles Open
We present an exploratory study carried out with a new miniature portable emission measurement system (Mini-PEMS) specifically designed at the Technical University of Liberec (CZ) for applications on two-wheeler vehicles owing to its reduc…
View article: Real-World Exhaust Emissions of Diesel Locomotives and Motorized Railcars during Scheduled Passenger Train Runs on Czech Railroads
Real-World Exhaust Emissions of Diesel Locomotives and Motorized Railcars during Scheduled Passenger Train Runs on Czech Railroads Open
The paper summarizes exhaust emissions measurements on two diesel-electric locomotives and one diesel-hydraulic railcar, each tested for several days during scheduled passenger service. While real driving emissions of buses decrease with f…
View article: Supplementary material to "A miniature Portable Emissions Measurement System (PEMS) for real-driving monitoring of motorcycles"
Supplementary material to "A miniature Portable Emissions Measurement System (PEMS) for real-driving monitoring of motorcycles" Open
View article: A miniature Portable Emissions Measurement System (PEMS) for real-driving monitoring of motorcycles
A miniature Portable Emissions Measurement System (PEMS) for real-driving monitoring of motorcycles Open
We present an exploratory study carried out with a new miniature portable emission measurement system (Mini-PEMS) specifically designed at the Technical University of Liberec (CZ) for applications on 2-wheeler vehicles owing to its reduced…
View article: Toxic responses in human lung epithelial cells (BEAS-2B) exposed to particulate matter exhaust emissions from gasoline and biogasoline
Toxic responses in human lung epithelial cells (BEAS-2B) exposed to particulate matter exhaust emissions from gasoline and biogasoline Open
Motor vehicle emissions substantially contribute to air pollution worldwide and cause serious health problems.While the deleterious effects of diesel exhaust particulate matter (PM) have been widely studied, much less attention is paid to …
View article: The Biological Effects of Complete Gasoline Engine Emissions Exposure in a 3D Human Airway Model (MucilAirTM) and in Human Bronchial Epithelial Cells (BEAS-2B)
The Biological Effects of Complete Gasoline Engine Emissions Exposure in a 3D Human Airway Model (MucilAirTM) and in Human Bronchial Epithelial Cells (BEAS-2B) Open
The biological effects induced by complete engine emissions in a 3D model of the human airway (MucilAirTM) and in human bronchial epithelial cells (BEAS-2B) grown at the air–liquid interface were compared. The cells were exposed for one or…