Michel Noubom
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View article: Genetic polymorphism of MSP2 and its implications for Plasmodium falciparum resistance in N’Djamena, Chad
Genetic polymorphism of MSP2 and its implications for Plasmodium falciparum resistance in N’Djamena, Chad Open
View article: Epidemiology of ovale, vivax and falciparum malaria in the highlands of Cameroon: An integrated community survey of human infection and vector abundance
Epidemiology of ovale, vivax and falciparum malaria in the highlands of Cameroon: An integrated community survey of human infection and vector abundance Open
Despite global malaria control efforts, the disease caused 263 million cases and 597,000 deaths in 2023. While Plasmodium falciparum accounts for most cases in Africa, non-falciparum species, such as P. ovale spp. and P. vivax, can cause r…
View article: Bloodstream infections in Cameroon: a systematic review and meta-analysis
Bloodstream infections in Cameroon: a systematic review and meta-analysis Open
This study reports a substantial prevalence of BSI and resistance to the commonly used antibiotics. It also points out the lack of compliance with international guidelines in microbiological analysis. This highlights the need to empower la…
View article: Epidemiology of ovale, vivax and falciparum malaria in the highlands of Cameroon: An integrated community survey of human infection and vector abundance
Epidemiology of ovale, vivax and falciparum malaria in the highlands of Cameroon: An integrated community survey of human infection and vector abundance Open
Despite global malaria control efforts, the disease caused 263 million cases and 597,000 deaths in 2023. While Plasmodium falciparum accounts for most cases in Africa, non-falciparum species, such as P. ovale spp . and P. vivax , can cause…
View article: Challenges on diagnosis and treatment of refractory adult-onset still disease in Sub-Saharan Africa: a case report
Challenges on diagnosis and treatment of refractory adult-onset still disease in Sub-Saharan Africa: a case report Open
Adult-onset-Still's disease is a rare pathology considered as a diagnosis of exclusion, which should be considered in the face of any fever of unknown origin. It is present in young adults over 16 years old, with an average peak at diagnos…
View article: Diabetes and metabolic syndrome in adults with malaria and associations with severe disease: results from two tertiary hospitals in Cameroon
Diabetes and metabolic syndrome in adults with malaria and associations with severe disease: results from two tertiary hospitals in Cameroon Open
Background The prevalence of lifestyle-associated diseases is increasing in sub-Saharan Africa. This study investigated the prevalence of metabolic co-morbidities in adults with malaria and whether type 2 diabetes, obesity, and metabolic s…
View article: Epidemiology of Relapsing and Falciparum Malaria in the Highlands of Cameroon: An Integrated Community Survey of Human Infection and Vector Abundance
Epidemiology of Relapsing and Falciparum Malaria in the Highlands of Cameroon: An Integrated Community Survey of Human Infection and Vector Abundance Open
Despite global malaria control efforts, the disease caused 263 million cases and 597,000 deaths in 2023. While Plasmodium falciparum accounts for most cases in Africa, non-falciparum species, such as P. ovale spp. and P. vivax , can cause …
View article: High prevalence of multidrug resistant and extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolated from urinary tract infections in the West region, Cameroon
High prevalence of multidrug resistant and extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolated from urinary tract infections in the West region, Cameroon Open
View article: Stress Hormones Released Pattern in Blood Donors and Its Impact on Blood Quality
Stress Hormones Released Pattern in Blood Donors and Its Impact on Blood Quality Open
Background and Objective: Blood transfusions are crucial medical procedures that can save lives. The release of stress hormones in the course of blood donation varies according to the characteristics of the donor and may render red cells v…
View article: Clonal Dissemination of Extended-Spectrum Beta-Lactamase (ESBL)- producing Klebsiella pneumoniae isolated from Medical devices and Hospital environments in the West region, Cameroon
Clonal Dissemination of Extended-Spectrum Beta-Lactamase (ESBL)- producing Klebsiella pneumoniae isolated from Medical devices and Hospital environments in the West region, Cameroon Open
Background Hospital-acquired infections (HAIs) caused by antibiotic resistant Klebsiella pneumoniae are serious public health concern globally. Extended-spectrum β-lactamase-producing Klebsiella pneumoniae (ESBL-K. pneumoniae) are major co…
View article: Occurrence of Extended-spectrum β-lactamase (ESBL) and Carbapenemase-producing Escherichia coli isolated from Childhood Diarrhoea in Yaoundé, Cameroon
Occurrence of Extended-spectrum β-lactamase (ESBL) and Carbapenemase-producing Escherichia coli isolated from Childhood Diarrhoea in Yaoundé, Cameroon Open
View article: Prevalence and Antibiotic Resistance Profile of Bacteria Isolated from Patients Pus at the Bafoussam Regional Hospital, West Region, Cameroon
Prevalence and Antibiotic Resistance Profile of Bacteria Isolated from Patients Pus at the Bafoussam Regional Hospital, West Region, Cameroon Open
View article: Multi-drug resistant (MDR) and extended-spectrum β-lactamase (ESBL) producing Escherichia coli isolated from slaughtered pigs and slaughterhouse workers in Yaoundé, Cameroon
Multi-drug resistant (MDR) and extended-spectrum β-lactamase (ESBL) producing Escherichia coli isolated from slaughtered pigs and slaughterhouse workers in Yaoundé, Cameroon Open
Antimicrobial resistance (AMR) in the food chain remains a global public health concern for both humans and animals. This study aimed to determine the prevalence, resistance profiles, and clonal relatedness of multidrug-resistant (MDR) and…
View article: Evaluation of Infected and Non-infected Wounds Healing Activity of Eriosema robustum Hydroethanolic Leaves Extract Ointments in Streptozotocin Induced Diabetic Rats
Evaluation of Infected and Non-infected Wounds Healing Activity of Eriosema robustum Hydroethanolic Leaves Extract Ointments in Streptozotocin Induced Diabetic Rats Open
Untreated diabetic wounds provide an optimal environment for bacterial growth, which, over time, can develop resistance to common antibiotics and ultimately result in amputation. Therefore, it is necessary to search for new sources of anti…
View article: Occurrence of extended-spectrum β-lactamase (ESBL) and carbapenemase-producing Escherichia coli isolated from childhood diarrhoea in Yaoundé, Cameroon
Occurrence of extended-spectrum β-lactamase (ESBL) and carbapenemase-producing Escherichia coli isolated from childhood diarrhoea in Yaoundé, Cameroon Open
Introduction: Extended-spectrum β-lactamase (ESBL)-producing pathogenic E. coli is a global public health issue, especially in sub-Saharan African countries such as Cameroon. It contributes to increase hospital length of stay, morbidity, m…
View article: Pterocarpus soyauxii (Fabaceae) aqueous extract to prevent neuropsychiatric disorders associated with menopause by triggering ROS-dependent oxidative damage and inhibiting acetylcholinesterase, GABA-transaminase, and monoamine oxidase A: In vitro, in vivo, and in silico approaches
Pterocarpus soyauxii (Fabaceae) aqueous extract to prevent neuropsychiatric disorders associated with menopause by triggering ROS-dependent oxidative damage and inhibiting acetylcholinesterase, GABA-transaminase, and monoamine oxidase A: In vitro, in vivo, and in silico approaches Open
Pterocarpus soyauxii (PS) is traditionally used in Cameroon medicine to alleviate postmenopausal symptoms. Previous research has shown that it has tissue-selective potential and estrogen-mimetic effects on vaginal atrophy. Phytoestr…
View article: Antisalmonella Activity and Modes of Action of Extracts, Fractions and Cerevisterol from Impatiens burtonii against Multi-Drug Resistant Salmonella
Antisalmonella Activity and Modes of Action of Extracts, Fractions and Cerevisterol from Impatiens burtonii against Multi-Drug Resistant Salmonella Open
Background: Typhoid fever is an endemic disease in developing countries, especially throughout Asia and Africa, which may lead to life-threatening conditions in the absence of adequate treatment. Objective: This study was aimed at determin…
View article: SARS-CoV-2 active infection and antibodies amongst health personnel during the outbreak in Cameroon: Strengthening the health system for response to future public health emergencies
SARS-CoV-2 active infection and antibodies amongst health personnel during the outbreak in Cameroon: Strengthening the health system for response to future public health emergencies Open
Background Health personnel (HP) are on the frontlines during response to public health emergencies like COVID-19. This risk of exposure suggests the need for safety in responding to any pandemic. Therefore, to ascertain the rate of SARS-C…
View article: High prevalence of multidrug resistant and extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolated from urinary tract infections in West region, Cameroon.
High prevalence of multidrug resistant and extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolated from urinary tract infections in West region, Cameroon. Open
Background Antimicrobial resistance remains a worldwide health problem with serious societal and economical repercussions. Multidrug resistant and Extended-Spectrum β-Lactamase producing-Enterobacterales (ESBL-E) are pathogens of critical …
View article: Epidemiology and Performances of Typhidot Immunoassay and Widal Slide Agglutination in the Diagnosis of Typhoid Fever in Febrile Patients in Bafoussam City, Cameroon: A Cross-Sectional Comparative Study
Epidemiology and Performances of Typhidot Immunoassay and Widal Slide Agglutination in the Diagnosis of Typhoid Fever in Febrile Patients in Bafoussam City, Cameroon: A Cross-Sectional Comparative Study Open
Background. Enteric fever is a great public health problem associated with significant illness and death in many endemic countries, and its clinical diagnosis is still daunting. The aim of this study was to determine the prevalence and ris…
View article: Bacterial Bloodstream Infections in Cameroon: A Systematic Review and Meta-Analysis of Prevalence and Antibiotic Resistance
Bacterial Bloodstream Infections in Cameroon: A Systematic Review and Meta-Analysis of Prevalence and Antibiotic Resistance Open
Background The paucity of data on the epidemiology of bloodstream infection (BSI) in low and middle-income countries (LMICs) limits its effective prevention and management. This review sought to determine the prevalence, bacteriological an…
View article: Uptake of intermittent preventive treatment of malaria in pregnancy and risk factors for maternal anaemia and low birthweight among HIV-negative mothers in Dschang, West region of Cameroon: a cross sectional study
Uptake of intermittent preventive treatment of malaria in pregnancy and risk factors for maternal anaemia and low birthweight among HIV-negative mothers in Dschang, West region of Cameroon: a cross sectional study Open
Background Approximately 32 million pregnant women are at risk of malaria with up to 10,000 maternal deaths and 200,000 neonates at risk annually. Intermittent Preventive Treatment (IPT) with sulfadoxine-pyrimethamine (SP) is recommended b…
View article: Biofilm Formation, Pyocyanin Production, and Antibiotic Resistance Profile of <i>Pseudomonas aeruginosa</i> Isolates from Wounds
Biofilm Formation, Pyocyanin Production, and Antibiotic Resistance Profile of <i>Pseudomonas aeruginosa</i> Isolates from Wounds Open
Pseudomonas aeruginosa is one of the most frequently resistant and dangerous bacteria isolated from infected wounds of patients. This study aimed to determine the prevalence of P. aeruginosa from infected wounds of patients in the Dschang …
View article: Antisamonellal Property and Modes of Action of Leaf Extracts of Dracaena deisteliana Engl. (Dracaenaceae)
Antisamonellal Property and Modes of Action of Leaf Extracts of Dracaena deisteliana Engl. (Dracaenaceae) Open
Background: In Cameroon, typhoid fever is after malaria, the disease with which health workers are most confronted because its incidence is constantly increasing. Salmonella has become over time multiresistant to antibiotics available on t…
View article: Diabetes Mellitus and HIV Infection among Newly Diagnosed Pulmonary Tuberculosis Patients in the North West Region of Cameroon: A Cross-Sectional Study
Diabetes Mellitus and HIV Infection among Newly Diagnosed Pulmonary Tuberculosis Patients in the North West Region of Cameroon: A Cross-Sectional Study Open
Objective. To determine the prevalence rate of HIV and diabetes among tuberculosis (TB) patients and also the comorbidity rate. Design. Cross-sectional study. Setting. This study was carried out at the Tuberculosis Reference Laboratory, Re…
View article: Phenotypic and genotypic characterization of multidrug resistant and extended-spectrum β-lactamase-producing Enterobacterales isolated from clinical samples in the western region in Cameroon
Phenotypic and genotypic characterization of multidrug resistant and extended-spectrum β-lactamase-producing Enterobacterales isolated from clinical samples in the western region in Cameroon Open
View article: Phenotypic and genotypic characterization of multidrug resistant (MDR) and extended-spectrum β-lactamase (ESBL)-producing Enterobacterales isolated from clinical samples in the Western region in Cameroon
Phenotypic and genotypic characterization of multidrug resistant (MDR) and extended-spectrum β-lactamase (ESBL)-producing Enterobacterales isolated from clinical samples in the Western region in Cameroon Open
Background : The 2017 World Health Organization (WHO) report has listed extended spectrum β-lactamases producing Enterobacterales (ESBL-PE) as critical pathogens for public health and requiring urgently new antibiotics. The aim of this stu…
View article: Antifungal Resistance Profile, Biofilm Formation, and Virulence Factor Production in Candida krusei Isolates From HIV-Infected Patients in Cameroon
Antifungal Resistance Profile, Biofilm Formation, and Virulence Factor Production in Candida krusei Isolates From HIV-Infected Patients in Cameroon Open
Background Fungal infections mainly caused by Candida krusei are increasing rapidly and represent a serious public health problem in human immunodeficiency virus (HIV)-infected patients. This study aimed to investigate the antifunga…
View article: Extended-Spectrum B-Lactamase (ESBL)-Producing Escherichia coli Isolated from Children under 5 years with and without Diarrhoea in Two Hospitals in Dschang, Cameroon
Extended-Spectrum B-Lactamase (ESBL)-Producing Escherichia coli Isolated from Children under 5 years with and without Diarrhoea in Two Hospitals in Dschang, Cameroon Open
Introduction: Extended-Spectrum β-Lactamase (ESBL) mediating resistance in Enterobacterales is a global public health issue, especially in Low-and Middle-Income Countries (LMICs) such as Cameroon. ESBL-producing Enterobacterales reduce the…
View article: Extended-Spectrum β-Lactamase-Producing Escherichia coli Isolated From Children Under 5 Years With and Without Diarrhoea in Two Hospitals in Dschang, Cameroon
Extended-Spectrum β-Lactamase-Producing Escherichia coli Isolated From Children Under 5 Years With and Without Diarrhoea in Two Hospitals in Dschang, Cameroon Open
Extended-spectrum β-lactamase (ESBL) mediating resistance in Enterobacterales is a global public health issue, especially in low-and middle-income countries (LMICs) such as Cameroon. ESBL-producing Enterobacterales reduce therapeutic optio…