Michel Thiry
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Efficacy of a Novel Antibody TLR3 Modulator in the Self-Treatment of Common Cold: The ESTUAR Trial Open
Context: Since the discovery of toll-like receptor 3 (TLR3), no specific tools have been developed to modulate its activity in upper respiratory tract viral infections (URTIs). ContafluTM (antibodies to TLR3 cytoplasmic fragment) is the fi…
Safety and Immunogenicity of rSh28GST Antigen in Humans: Phase 1 Randomized Clinical Study of a Vaccine Candidate against Urinary Schistosomiasis Open
rSh28GST in Alum did not induce any significant toxicity in healthy adults and generated a Th2-type immune response. Together with previous preclinical results, the data of safety, tolerability and quality of the specific immune response p…
Eighteen years of vaccination against viral haemorrhagic septicaemia in France. Open
Viral haemorrhagic septicaemia (VHS) has been considered for many years to be a major cause of loss in the French trout industry. The high prevalence of VHS in certain geographic areas made a control strategy based on control policy unfeas…
Recombinant protein fragments from haemorrhagic septicaemia rhabdovirus stimulate trout leukocyte anamnestic responses in vitro Open
This work shows that viral protein fragments are capable of stimulating fish anamnestic immunological responses in leukocytes from the rainbow trout (Oncorhynchus mykiss, W.). Recombinant protein fragments of glycoprotein and nucleoprotein…
Nucleotide Sequence of the Lipase Gene <i>lip2</i> from the Antarctic Psychrotroph <i>Moraxella</i> TA 144 and Site-Specific Mutagenesis of the Conserved Serine and Histidine Residues Open
The lip2 gene from the antarctic psychotroph Moraxella TA144 was sequenced. The primary structure of the Lip2 preprotein deduced from the nucleotide sequence is composed of 433 amino acids with a predicted Mr of 47,222. This enzyme contain…
Sequence of a lipase gene from the Antarctic psychrotroph<i>Moraxella</i>TA144 Open
peer reviewed
Lipases from psychrotropic antarctic bacteria Open
Properties of lipases excreted by 4 psychrotropic Moraxella strains from antarctic sea water have investigated. Despite an optimal cell generation time at 25°C, maximal lipase excretion essentially occurs at low temperatures. These enzymes…