Michele Bozzi
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View article: Non-stenotic fibro-calcific aortic valve as a predictor of myocardial infarction recurrence
Non-stenotic fibro-calcific aortic valve as a predictor of myocardial infarction recurrence Open
Aims Patients with acute myocardial infarction (AMI) are at increased risk of recurrent cardiovascular events. Non-stenotic aortic valve fibro-calcific remodelling (called aortic valve sclerosis; AVSc), reflecting systemic damage, may serv…
View article: Anti-Inflammation and Anti-Oxidation: The Key to Unlocking the Cardiovascular Potential of SGLT2 Inhibitors and GLP1 Receptor Agonists
Anti-Inflammation and Anti-Oxidation: The Key to Unlocking the Cardiovascular Potential of SGLT2 Inhibitors and GLP1 Receptor Agonists Open
Type 2 diabetes mellitus (T2DM) is a prevalent and complex metabolic disorder associated with various complications, including cardiovascular diseases. Sodium-glucose co-transporter 2 inhibitors (SGLT2i) and glucagon-like peptide 1 recepto…
View article: Patients with acute myocardial infarction and aortic valve sclerosis have an increased risk of recurrent myocardial infarction
Patients with acute myocardial infarction and aortic valve sclerosis have an increased risk of recurrent myocardial infarction Open
Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): Gigi e Pupa Ferrari ONLUS. Background It has been shown that atherosclerosis risk factors have been associated with aortic valve sclerosis (AVSc) and tha…
View article: Aortic valve sclerosis in patients with acute myocardial infarction: a marker of increased risk of re-infarction
Aortic valve sclerosis in patients with acute myocardial infarction: a marker of increased risk of re-infarction Open
Background Patients with acute myocardial infarction (AMI) are at increased risk of recurrent cardiovascular events. Aortic valve sclerosis (AVSc), which reflects a systemic damage, may serve as a marker of risk. The aim of the present stu…
View article: Efficacy of cardiometabolic drugs in reduction of epicardial adipose tissue: a systematic review and meta-analysis
Efficacy of cardiometabolic drugs in reduction of epicardial adipose tissue: a systematic review and meta-analysis Open
Background Epicardial adipose tissue (EAT) plays an important role in cardiometabolic risk. EAT is a modifiable risk factor and could be a potential therapeutic target for drugs that already show cardiovascular benefits . The aim of this s…
View article: Dataset related to the article "Extraction-Free Absolute Quantification of Circulating miRNAs by Chip-Based Digital PCR"
Dataset related to the article "Extraction-Free Absolute Quantification of Circulating miRNAs by Chip-Based Digital PCR" Open
This record contains raw data related to the article "Extraction-Free Absolute Quantification of Circulating miRNAs by Chip-Based Digital PCR" Circulating microRNAs (miRNA) have been proposed as specific biomarkers for several diseases. Qu…
View article: Dataset related to the article "Purinergic Receptor P2Y2 Stimulation Averts Aortic Valve Interstitial Cell Calcification and Myofibroblastic Activation"
Dataset related to the article "Purinergic Receptor P2Y2 Stimulation Averts Aortic Valve Interstitial Cell Calcification and Myofibroblastic Activation" Open
This record contains raw data related to the article "Purinergic Receptor P2Y2 Stimulation Averts Aortic Valve Interstitial Cell Calcification and Myofibroblastic Activation" Rationale-Calcific aortic valve stenosis (CAVS) is a pathologica…
View article: Dataset related to the article "Purinergic Receptor P2Y2 Stimulation Averts Aortic Valve Interstitial Cell Calcification and Myofibroblastic Activation"
Dataset related to the article "Purinergic Receptor P2Y2 Stimulation Averts Aortic Valve Interstitial Cell Calcification and Myofibroblastic Activation" Open
This record contains raw data related to the article "Purinergic Receptor P2Y2 Stimulation Averts Aortic Valve Interstitial Cell Calcification and Myofibroblastic Activation" Rationale-Calcific aortic valve stenosis (CAVS) is a pathologica…
View article: Dataset related to the article "Extraction-Free Absolute Quantification of Circulating miRNAs by Chip-Based Digital PCR"
Dataset related to the article "Extraction-Free Absolute Quantification of Circulating miRNAs by Chip-Based Digital PCR" Open
This record contains raw data related to the article "Extraction-Free Absolute Quantification of Circulating miRNAs by Chip-Based Digital PCR" Circulating microRNAs (miRNA) have been proposed as specific biomarkers for several diseases. Qu…
View article: Extraction-Free Absolute Quantification of Circulating miRNAs by Chip-Based Digital PCR
Extraction-Free Absolute Quantification of Circulating miRNAs by Chip-Based Digital PCR Open
Circulating microRNAs (miRNA) have been proposed as specific biomarkers for several diseases. Quantitative Real-Time PCR (RT-qPCR) is the gold standard technique currently used to evaluate miRNAs expression from different sources. In the l…
View article: Sex-specific cell types and molecular pathways drive fibro-calcific aortic valve stenosis
Sex-specific cell types and molecular pathways drive fibro-calcific aortic valve stenosis Open
Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): Fondazione Gigi e Pupa Ferrari ONLUS Background Aortic stenosis (AS) is the most common valve disorder characterized by fibro-calcific remodeling of valv…
View article: Unravelling sex-dependent mechanisms in calcific aortic valve stenosis
Unravelling sex-dependent mechanisms in calcific aortic valve stenosis Open
Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): Italian Ministry of Health Background Calcific aortic valve stenosis (CAVS) is the most common heart valve disease that affects 3% of the popu…
View article: Purinergic Receptor P2Y2 Stimulation Averts Aortic Valve Interstitial Cell Calcification and Myofibroblastic Activation
Purinergic Receptor P2Y2 Stimulation Averts Aortic Valve Interstitial Cell Calcification and Myofibroblastic Activation Open
Rationale—Calcific aortic valve stenosis (CAVS) is a pathological condition of the aortic valve with a prevalence of 3% in the general population. It is characterized by massive rearrangement of the extracellular matrix, mostly due to the …