Benjamin Zimmerman
YOU?
Author Swipe
View article: Kinetics of thromboxane A2 receptor-driven vascular tone in the cerebral cortex ex vivo
Kinetics of thromboxane A2 receptor-driven vascular tone in the cerebral cortex ex vivo Open
Ex vivo imaging in acute cortical brain slices is a valuable tool to assess neurovascular coupling and is particularly useful for studying active, local changes in microvascular compartments in isolation from upstream or downstream changes…
View article: Dietary associations with reduced epigenetic age: a secondary data analysis of the methylation diet and lifestyle study
Dietary associations with reduced epigenetic age: a secondary data analysis of the methylation diet and lifestyle study Open
In hierarchical linear regression, foods investigated as polyphenolic modulators of DNA methylation (green tea, oolong tea, turmeric, rosemary, garlic, berries) categorized in the original study as methyl adaptogens showed significant line…
View article: The Influence of X Chromosome Parent-of-Origin on Glycemia in Individuals with Turner Syndrome
The Influence of X Chromosome Parent-of-Origin on Glycemia in Individuals with Turner Syndrome Open
Introduction: The cause of increased diabetes mellitus (DM) risk in individuals with Turner syndrome (TS) is poorly understood. Parent-of-origin effects related to whether the maternal or paternal X chromosome (Xchr) remains intact have be…
View article: Neurovascular mechanisms of cognitive aging: Sex-related differences in the average progression of arteriosclerosis, white matter atrophy, and cognitive decline
Neurovascular mechanisms of cognitive aging: Sex-related differences in the average progression of arteriosclerosis, white matter atrophy, and cognitive decline Open
View article: Hemodynamic cortical ripples through cyclicity analysis
Hemodynamic cortical ripples through cyclicity analysis Open
A fine-grained understanding of dynamics in cortical networks is crucial to unpacking brain function. Resting-state functional magnetic resonance imaging (fMRI) gives rise to time series recordings of the activity of different brain region…
View article: Neurovascular Mechanisms of Cognitive Aging: Sex-Related Differences in the Average Progression of Arteriosclerosis, White Matter Atrophy, and Cognitive Decline
Neurovascular Mechanisms of Cognitive Aging: Sex-Related Differences in the Average Progression of Arteriosclerosis, White Matter Atrophy, and Cognitive Decline Open
Arterial stiffness (arteriosclerosis) has been linked to heightened risks for cognitive decline, and ultimately for Alzheimer’s disease and other forms of dementia. Importantly, neurovascular outcomes generally vary according to one’s biol…
View article: Age, sex, and apolipoprotein E isoform alter contextual fear learning, neuronal activation, and baseline DNA damage in the hippocampus
Age, sex, and apolipoprotein E isoform alter contextual fear learning, neuronal activation, and baseline DNA damage in the hippocampus Open
Age, female sex, and apolipoprotein E4 (E4) are risk factors to develop Alzheimer’s disease (AD). There are three major human apoE isoforms: E2, E3, and E4. Compared to E3, E4 increases while E2 decreases AD risk. However, E2 is associated…
View article: Serum Levels of α-Klotho Are Correlated with Cerebrospinal Fluid Levels and Predict Measures of Cognitive Function
Serum Levels of α-Klotho Are Correlated with Cerebrospinal Fluid Levels and Predict Measures of Cognitive Function Open
Background: α-klotho might play a role in neurodegenerative diseases. Objective: To determine levels of α-klotho and apoE in serum and cerebrospinal fluid (CSF) samples and their relationship with the Mini-Mental State Examination (MMSE) a…
View article: Amifostine (WR-2721) Mitigates Cognitive Injury Induced by Heavy Ion Radiation in Male Mice and Alters Behavior and Brain Connectivity
Amifostine (WR-2721) Mitigates Cognitive Injury Induced by Heavy Ion Radiation in Male Mice and Alters Behavior and Brain Connectivity Open
The deep space environment contains many risks to astronauts during space missions, such as galactic cosmic rays (GCRs) comprised of naturally occurring heavy ions. Heavy ion radiation is increasingly being used in cancer therapy, includin…
View article: Apolipoprotein E levels in the amygdala and prefrontal cortex predict relative regional brain volumes in irradiated Rhesus macaques
Apolipoprotein E levels in the amygdala and prefrontal cortex predict relative regional brain volumes in irradiated Rhesus macaques Open
View article: The Effect of High Fat Diet on Cerebrovascular Health and Pathology: A Species Comparative Review
The Effect of High Fat Diet on Cerebrovascular Health and Pathology: A Species Comparative Review Open
In both humans and animal models, consumption of a high-saturated-fat diet has been linked to vascular dysfunction and cognitive impairments. Laboratory animals provide excellent models for more invasive high-fat-diet-related research. How…
View article: Slow Cortical Waves through Cyclicity Analysis
Slow Cortical Waves through Cyclicity Analysis Open
Fine-grained understanding of dynamics in cortical networks is crucial in unpacking brain function. Here, we introduce a novel analytical method to characterize the dynamic interaction between distant brain regions, and apply it to data fr…
View article: Age‐related changes in cerebrovascular health and their effects on neural function and cognition: A comprehensive review
Age‐related changes in cerebrovascular health and their effects on neural function and cognition: A comprehensive review Open
The process of aging includes changes in cellular biology that affect local interactions between cells and their environments and eventually propagate to systemic levels. In the brain, where neurons critically depend on an efficient and dy…
View article: High-resolution magnetic resonance imaging-based atlases for the young and adolescent domesticated pig (Sus scrofa)
High-resolution magnetic resonance imaging-based atlases for the young and adolescent domesticated pig (Sus scrofa) Open
Two high-resolution MRI brain atlases specific to the domesticated young and adolescent pig were created using defined image acquisition and data processing methods to facilitate the generation of high-quality normative data for neurodevel…
View article: Decreased resting perfusion in precuneus and posterior cingulate cortex predicts tinnitus severity
Decreased resting perfusion in precuneus and posterior cingulate cortex predicts tinnitus severity Open
View article: Longitudinal Effects of Immediate and Delayed Estradiol on Cognitive Performance in a Spatial Maze and Hippocampal Volume in Menopausal Macaques Under an Obesogenic Diet
Longitudinal Effects of Immediate and Delayed Estradiol on Cognitive Performance in a Spatial Maze and Hippocampal Volume in Menopausal Macaques Under an Obesogenic Diet Open
The consumption of a diet high in fat and refined sugars has several health risks, including the development of cognitive decline and neurodegeneration. For women, menopause carries additional health risks that may interact with a high-fat…
View article: Comparing Cyclicity Analysis With Pre-established Functional Connectivity Methods to Identify Individuals and Subject Groups Using Resting State fMRI
Comparing Cyclicity Analysis With Pre-established Functional Connectivity Methods to Identify Individuals and Subject Groups Using Resting State fMRI Open
The resting state fMRI time series appears to have cyclic patterns, which indicates presence of cyclic interactions between different brain regions. Such interactions are not easily captured by pre-established resting state functional conn…
View article: Age-related differences in functional brain network segregation are consistent with a cascade of cerebrovascular, structural, and cognitive effects
Age-related differences in functional brain network segregation are consistent with a cascade of cerebrovascular, structural, and cognitive effects Open
Age-related declines in cognition are associated with widespread structural and functional brain changes, including changes in resting-state functional connectivity and gray and white matter status. Recently we have shown that the elastici…
View article: Optical measures of cerebral arterial stiffness are associated with white matter signal abnormalities and cognitive performance in normal aging
Optical measures of cerebral arterial stiffness are associated with white matter signal abnormalities and cognitive performance in normal aging Open
View article: Functional Brain Changes During Mindfulness-Based Cognitive Therapy Associated With Tinnitus Severity
Functional Brain Changes During Mindfulness-Based Cognitive Therapy Associated With Tinnitus Severity Open
Mindfulness-based therapies have been introduced as a treatment option to reduce the psychological severity of tinnitus, a currently incurable chronic condition. This pilot study of twelve subjects with chronic tinnitus investigates the re…
View article: The Optical Effective Attenuation Coefficient as an Informative Measure of Brain Health in Aging
The Optical Effective Attenuation Coefficient as an Informative Measure of Brain Health in Aging Open
Aging is accompanied by widespread changes in brain tissue. Here, we hypothesized that head tissue opacity to near-infrared light provides information about the health status of the brain’s cortical mantle. In diffusive media such as the h…
View article: Publisher Correction: Large-area MRI-compatible epidermal electronic interfaces for prosthetic control and cognitive monitoring
Publisher Correction: Large-area MRI-compatible epidermal electronic interfaces for prosthetic control and cognitive monitoring Open
View article: Dissociating tinnitus patients from healthy controls using resting-state cyclicity analysis and clustering
Dissociating tinnitus patients from healthy controls using resting-state cyclicity analysis and clustering Open
Chronic tinnitus is a common and sometimes debilitating condition that lacks scientific consensus on physiological models of how the condition arises as well as any known cure. In this study, we applied a novel cyclicity analysis, which st…
View article: Individual differences in regional cortical volumes across the life span are associated with regional optical measures of arterial elasticity
Individual differences in regional cortical volumes across the life span are associated with regional optical measures of arterial elasticity Open
View article: Understanding the role of cerebrovascular health in cognitive aging: a multi-modal noninvasive human neuroimaging approach
Understanding the role of cerebrovascular health in cognitive aging: a multi-modal noninvasive human neuroimaging approach Open
The brain’s vasculature undergoes age-related physiological and anatomical changes similarly to the rest of the cardiovascular system. However, the health of the cerebrovasculature may be related to cognitive ability. Thus, it is critical …
View article: Mapping cerebral pulse pressure and arterial compliance over the adult lifespan with optical imaging
Mapping cerebral pulse pressure and arterial compliance over the adult lifespan with optical imaging Open
Cerebrovascular health is important for maintaining a high level of cognitive performance, not only in old age, but also throughout the lifespan. Recently, it was first demonstrated that diffuse optical imaging measures of pulse amplitude …
View article: Battery-free, stretchable optoelectronic systems for wireless optical characterization of the skin
Battery-free, stretchable optoelectronic systems for wireless optical characterization of the skin Open
Stretchable, wireless health monitoring patches to evaluate heart rate, blood oximetry, UV exposure, and skin coloration.
View article: Comparing Aging and Fitness Effects on Brain Anatomy
Comparing Aging and Fitness Effects on Brain Anatomy Open
Recent studies suggest that cardiorespiratory fitness (CRF) mitigates the brain's atrophy typically associated with aging, via a variety of beneficial mechanisms. One could argue that if CRF is generally counteracting the negative effects …
View article: Optical measures of changes in cerebral vascular tone during voluntary breath holding and a Sternberg memory task
Optical measures of changes in cerebral vascular tone during voluntary breath holding and a Sternberg memory task Open
View article: Poster Session Abstracts
Poster Session Abstracts Open
Expectancies concerning how people will act are formed from acquired knowledge about what those other people are like, and are used to interpret their ongoing behaviors (see Olson, Roese, & Zanna, 1996). Previous person perception research…