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View article: Development of Novel Symptom Score to Assist in Screening for Exocrine Pancreatic Insufficiency
Development of Novel Symptom Score to Assist in Screening for Exocrine Pancreatic Insufficiency Open
Background: Exocrine pancreatic insufficiency (EPI or PEI) often goes undiagnosed or misdiagnosed due to nonspecific symptomatology. Clinicians may focus primarily on symptoms like diarrhea and steatorrhea, potentially overlooking more pre…
View article: Diabetes Has Minimal Effect on High Gastrointestinal Symptom Burden in Exocrine Pancreatic Insufficiency Based on EPI/PEI-SS Scores
Diabetes Has Minimal Effect on High Gastrointestinal Symptom Burden in Exocrine Pancreatic Insufficiency Based on EPI/PEI-SS Scores Open
Background: Exocrine pancreatic insufficiency (EPI or PEI) may be prevalent in as many as 3 of 10 people with diabetes due to exocrine pancreatic function being reduced as early as the time of diagnosis. EPI can be treated with pancreatic …
View article: Bridging the Divide in Digital Therapeutics (DTx): Partnership Strategies for Broader Representation Across DTx Development and Deployment
Bridging the Divide in Digital Therapeutics (DTx): Partnership Strategies for Broader Representation Across DTx Development and Deployment Open
While Digital Therapeutics (DTx) are widely considered a key strategy to reach certain populations with unmet healthcare needs, a range of differences in the impact and adoption of DTx still exists. These differences are not just rooted in…
View article: Harnessing AI for Patient Engagement in a Study on Large Language Models and Open Notes
Harnessing AI for Patient Engagement in a Study on Large Language Models and Open Notes Open
BackgroundThe use of large language models (LLMs) is growing for both clinicians and patients. While researchers and clinicians have explored LLMs to manage patient portal messages and reduce burnout, there is less documentation about how …
View article: Correction: Examining the Emotional and Physical Health Impact in Users of Open-Source Automated Insulin Delivery and Sources of Support: Qualitative Analysis of Patient Narratives
Correction: Examining the Emotional and Physical Health Impact in Users of Open-Source Automated Insulin Delivery and Sources of Support: Qualitative Analysis of Patient Narratives Open
[This corrects the article DOI: 10.2196/48406.].
View article: A proof-of-concept study for patient use of open notes with large language models
A proof-of-concept study for patient use of open notes with large language models Open
Objectives The use of large language models (LLMs) is growing for both clinicians and patients. While researchers and clinicians have explored LLMs to manage patient portal messages and reduce burnout, there is less documentation about how…
View article: Harnessing AI for Patient Engagement in a Study on Large Language Models and Open Notes
Harnessing AI for Patient Engagement in a Study on Large Language Models and Open Notes Open
BackgroundThe use of large language models (LLMs) is growing for both clinicians and patients. While researchers and clinicians have explored LLMs to manage patient portal messages and reduce burnout, there is less documentation about how …
View article: Harnessing AI for Patient Engagement in a Study on Large Language Models and Open Notes
Harnessing AI for Patient Engagement in a Study on Large Language Models and Open Notes Open
BackgroundThe use of large language models (LLMs) is growing for both clinicians and patients. While researchers and clinicians have explored LLMs to manage patient portal messages and reduce burnout, there is less documentation about how …
View article: Impact of Hypoglycemia on Glucose Variability over Time for Individuals with Open-Source Automated Insulin Delivery Systems
Impact of Hypoglycemia on Glucose Variability over Time for Individuals with Open-Source Automated Insulin Delivery Systems Open
This study investigates glucose conditions preceding and following various hypoglycemia levels in individuals with type 1 diabetes using open-source automated insulin delivery (AID) systems. It also seeks to evaluate relationships between …
View article: Man with a painful red eye
Man with a painful red eye Open
View article: Refining Insulin on Board with netIOB for Automated Insulin Delivery
Refining Insulin on Board with netIOB for Automated Insulin Delivery Open
Automated insulin delivery (AID) systems enhance glucose management by lowering mean glucose level, reducing hyperglycemia, and minimizing hypoglycemia. One feature of most AID systems is that they allow the user to view “insulin on board”…
View article: Diabetes Has Minimal Effect On High Gastrointestinal Symptom Burden in Exocrine Pancreatic Insufficiency Based On EPI/PEI-SS Scores
Diabetes Has Minimal Effect On High Gastrointestinal Symptom Burden in Exocrine Pancreatic Insufficiency Based On EPI/PEI-SS Scores Open
Background: Exocrine pancreatic insufficiency (EPI or PEI) may be prevalent in as many as 3 of 10 people with diabetes, due to exocrine pancreatic function reduced as early as the time of diagnosis. EPI can be treated with pancreatic enzym…
View article: Examining the Emotional and Physical Health Impact in Users of Open-Source Automated Insulin Delivery and Sources of Support: Qualitative Analysis of Patient Narratives
Examining the Emotional and Physical Health Impact in Users of Open-Source Automated Insulin Delivery and Sources of Support: Qualitative Analysis of Patient Narratives Open
Background Although commercially developed automated insulin delivery (AID) systems have recently been approved and become available in a limited number of countries, they are not universally available, accessible, or affordable. Therefore…
View article: Impact of Hypoglycemia on Glucose Variability Over Time for Individuals with Open Source Automated Insulin Delivery Systems
Impact of Hypoglycemia on Glucose Variability Over Time for Individuals with Open Source Automated Insulin Delivery Systems Open
Background: This study investigates glucose conditions preceding and following various hypoglycemia levels in individuals with type 1 diabetes using open-source automated insulin delivery (AID) systems. It also seeks to evaluate relationsh…
View article: Novel Exocrine Pancreatic Insufficiency Symptom Score May Improve Screening For Pancreatic Exocrine Insufficiency
Novel Exocrine Pancreatic Insufficiency Symptom Score May Improve Screening For Pancreatic Exocrine Insufficiency Open
Background and Aims: Exocrine Pancreatic Insufficiency (EPI) often goes undiagnosed or misdiagnosed due to its nonspecific symptomatology. Traditionally, clinicians may focus primarily on symptoms like diarrhea and steatorrhea, potentially…
View article: An Updated Review of Exocrine Pancreatic Insufficiency Prevalence finds EPI to be More Common in General Population than Rates of Co-Conditions
An Updated Review of Exocrine Pancreatic Insufficiency Prevalence finds EPI to be More Common in General Population than Rates of Co-Conditions Open
Exocrine pancreatic insufficiency (EPI) is frequently described as underscreened, underdiagnosed, and undertreated. The treatment for EPI is pancreatic enzyme replacement therapy (PERT), which is costly, and provider confidence in prescrib…
View article: Psychosocial Outcomes Among Users and Nonusers of Open-Source Automated Insulin Delivery Systems: Multinational Survey of Adults With Type 1 Diabetes
Psychosocial Outcomes Among Users and Nonusers of Open-Source Automated Insulin Delivery Systems: Multinational Survey of Adults With Type 1 Diabetes Open
Background Emerging research suggests that open-source automated insulin delivery (AID) may reduce diabetes burden and improve sleep quality and quality of life (QoL). However, the evidence is mostly qualitative or uses unvalidated, study-…
View article: Navigating Ambiguities in Exocrine Pancreatic Insufficiency
Navigating Ambiguities in Exocrine Pancreatic Insufficiency Open
The recent "AGA Clinical Practice Update on the Epidemiology, Evaluation, and Management of Exocrine Pancreatic Insufficiency (EPI)" by Whitcomb et al. seeks to increase awareness of and treatment for EPI (also known as PEI or PI) among cl…
View article: Glucose Variability Analysis in Two Large-Scale and Real-World Data Sets of Open-Source Automated Insulin Delivery Systems
Glucose Variability Analysis in Two Large-Scale and Real-World Data Sets of Open-Source Automated Insulin Delivery Systems Open
Background: Open-source automated insulin delivery (OS-AID) systems combine commercially available insulin pumps and continuous glucose monitors with open-source algorithms to automate insulin dosing for people with insulin-requiring diabe…
View article: Survey of Pancreatic Enzyme Replacement Therapy Dosing Experiences in Adults with Exocrine Pancreatic Insufficiency
Survey of Pancreatic Enzyme Replacement Therapy Dosing Experiences in Adults with Exocrine Pancreatic Insufficiency Open
Objectives: Pancreatic enzyme replacement therapy (PERT) is essential for treating exocrine pancreatic insufficiency (EPI), a condition where the pancreas does not produce adequate enzymes for digestion. This study delves into the real-wor…
View article: Harnessing wearables and mobile phones to improve glycemic outcomes with automated insulin delivery
Harnessing wearables and mobile phones to improve glycemic outcomes with automated insulin delivery Open
There is increasing interest in incorporating wearable and mobile phone data, including heart rate and accelerometer data, into automated insulin delivery (AID) systems to improve glucose outcomes and reduce burden on people living with di…
View article: Examining the Emotional and Physical Health Impact in Users of Open-Source Automated Insulin Delivery and Sources of Support: Qualitative Analysis of Patient Narratives (Preprint)
Examining the Emotional and Physical Health Impact in Users of Open-Source Automated Insulin Delivery and Sources of Support: Qualitative Analysis of Patient Narratives (Preprint) Open
BACKGROUND Although commercially developed automated insulin delivery (AID) systems have recently been approved and become available in a limited number of countries, they are not universally available, accessible, or affordable. Therefor…
View article: Interviews with Indigenous Māori with type 1 diabetes using open-source automated insulin delivery in the CREATE randomised trial
Interviews with Indigenous Māori with type 1 diabetes using open-source automated insulin delivery in the CREATE randomised trial Open
Purpose Open-source automated insulin delivery (AID) is used by thousands of people with type 1 diabetes (T1D), but has unknown generalisability to marginalised ethnic groups. This study explored experiences of Indigenous Māori participant…
View article: Long-Term Glucose Forecasting for Open-Source Automated Insulin Delivery Systems: A Machine Learning Study with Real-World Variability Analysis
Long-Term Glucose Forecasting for Open-Source Automated Insulin Delivery Systems: A Machine Learning Study with Real-World Variability Analysis Open
Glucose forecasting serves as a backbone for several healthcare applications, including real-time insulin dosing in people with diabetes and physical activity optimization. This paper presents a study on the use of machine learning (ML) an…
View article: From Individuals to Systems and Contributions to Creations: Novel Framework for Mapping the Efforts of Individuals by Convening The Center of Health and Health Care
From Individuals to Systems and Contributions to Creations: Novel Framework for Mapping the Efforts of Individuals by Convening The Center of Health and Health Care Open
Background People with lived health care experiences (often referred to as “patients”) are increasingly contributing to health care and are most effective when they are involved as partners who can contribute complementary knowledge alongs…
View article: Open-Source Automated Insulin Delivery in Type 1 Diabetes
Open-Source Automated Insulin Delivery in Type 1 Diabetes Open
In children and adults with type 1 diabetes, the use of an open-source AID system resulted in a significantly higher percentage of time in the target glucose range than the use of a sensor-augmented insulin pump at 24 weeks. (Supported by …
View article: Practical Guidance on Open Source and Commercial Automated Insulin Delivery Systems: A Guide for Healthcare Professionals Supporting People with Insulin-Requiring Diabetes
Practical Guidance on Open Source and Commercial Automated Insulin Delivery Systems: A Guide for Healthcare Professionals Supporting People with Insulin-Requiring Diabetes Open
View article: Barriers to Uptake of Open-Source Automated Insulin Delivery Systems: Analysis of Socioeconomic Factors and Perceived Challenges of Caregivers of Children and Adolescents With Type 1 Diabetes From the OPEN Survey
Barriers to Uptake of Open-Source Automated Insulin Delivery Systems: Analysis of Socioeconomic Factors and Perceived Challenges of Caregivers of Children and Adolescents With Type 1 Diabetes From the OPEN Survey Open
Background As a treatment option for people living with diabetes, automated insulin delivery (AID) systems are becoming increasingly popular. The #WeAreNotWaiting community plays a crucial role in the provision and distribution of open-sou…
View article: Glycemic Variability Assessment in Newly Treated Exocrine Pancreatic Insufficiency With Type 1 Diabetes
Glycemic Variability Assessment in Newly Treated Exocrine Pancreatic Insufficiency With Type 1 Diabetes Open
Background: Thirty-nine percent of people with type 1 diabetes may have lowered pancreatic elastase levels, correlated with exocrine pancreatic insufficiency (EPI or PEI). EPI is treated with oral supplementation of pancreatic enzymes. Lit…
View article: Understanding the needs of people aging with type 1 diabetes: a user-focused research study with prototype diabetes advance directive and setting the stage for future research
Understanding the needs of people aging with type 1 diabetes: a user-focused research study with prototype diabetes advance directive and setting the stage for future research Open