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View article: Immunocompetent Cell Targeting by Food-Additive Titanium Dioxide
Immunocompetent Cell Targeting by Food-Additive Titanium Dioxide Open
Food-grade titanium dioxide (fgTiO 2 ) is a bio-persistent particle under intense regulatory scrutiny. Paradoxically, meaningful in vivo cellular accumulation has never been demonstrated: the only known cell reservoirs for fgTiO 2 are ‘gra…
View article: Image‐Based Cell Profiling Enables Quantitative Tissue Microscopy in Gastroenterology
Image‐Based Cell Profiling Enables Quantitative Tissue Microscopy in Gastroenterology Open
Immunofluorescence microscopy is an essential tool for tissue‐based research, yet data reporting is almost always qualitative. Quantification of images, at the per‐cell level, enables “flow cytometry‐type” analyses with intact locational d…
View article: A Murine Oral‐Exposure Model for Nano‐ and Micro‐Particulates: Demonstrating Human Relevance with Food‐Grade Titanium Dioxide
A Murine Oral‐Exposure Model for Nano‐ and Micro‐Particulates: Demonstrating Human Relevance with Food‐Grade Titanium Dioxide Open
Human exposure to persistent, nonbiological nanoparticles and microparticles via the oral route is continuous and large scale (10 12 –10 13 particles per day per adult in Europe). Whether this matters or not is unknown but confirmed health…