Michelle Seiler
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View article: Editorial: COVID-19 - lessons learned in pediatrics
Editorial: COVID-19 - lessons learned in pediatrics Open
View article: Multivendor comparison study of artificial intelligence software for automated fracture detection in paediatric patients
Multivendor comparison study of artificial intelligence software for automated fracture detection in paediatric patients Open
Background Evidence for artificial intelligence (AI)-assisted paediatric fracture detection is limited. External validation and comparison of AI software are required before reliable use in clinical practice. Objective To evaluate and comp…
View article: Rapid diagnosis of pediatric nonconvulsive status epilepticus using point-of-care EEG
Rapid diagnosis of pediatric nonconvulsive status epilepticus using point-of-care EEG Open
Although all cases followed convulsive seizures, pocEEG may also assist in detecting NCSE in children with unexplained AMS and no seizure history. In our PED, pocEEG provided a pragmatic alternative that enabled early diagnosis and treatme…
View article: Implementation of point-of-care EEG in a pediatric emergency department: a quality improvement study
Implementation of point-of-care EEG in a pediatric emergency department: a quality improvement study Open
View article: Opioid Administration and Reduction of Pediatric Ileocolic Intussusception
Opioid Administration and Reduction of Pediatric Ileocolic Intussusception Open
Importance Ileocolic intussusception is an important and painful cause of bowel obstruction in children. Its reduction is also painful, but neither sedation nor analgesia is routinely provided, in part due to concerns surrounding gastroint…
View article: E-Learning for Pediatric Emergency Department Staff in Point-of-Care Electroencephalogram Interpretation: Prospective Cohort Study
E-Learning for Pediatric Emergency Department Staff in Point-of-Care Electroencephalogram Interpretation: Prospective Cohort Study Open
Background Status epilepticus (SE) represents a critical pediatric emergency necessitating prompt treatment and monitoring. The diagnosis of nonconvulsive SE and the monitoring of convulsive SE require electroencephalogram (EEG) recordings…
View article: One size doesn’t fit all: regional dynamics in pediatric emergency visits during the SARS-CoV-2 pandemic
One size doesn’t fit all: regional dynamics in pediatric emergency visits during the SARS-CoV-2 pandemic Open
Background and aims The Swiss government implemented lockdown measures during the COVID-19 pandemic to contain outbreaks and prevent healthcare system overload. Emergency department (ED) visits were discouraged, leading to a decline in uti…
View article: Evolving clinical features of Mycoplasma pneumoniae infections following COVID-19 pandemic restrictions: a retrospective, comparative cohort study
Evolving clinical features of Mycoplasma pneumoniae infections following COVID-19 pandemic restrictions: a retrospective, comparative cohort study Open
View article: Data collection in pediatric outpatient settings during the SARS-CoV-2 pandemic: motivators and barriers to establishing a research network of primary care providers
Data collection in pediatric outpatient settings during the SARS-CoV-2 pandemic: motivators and barriers to establishing a research network of primary care providers Open
The study demonstrated the feasibility of regional data collection within a cantonal network, yielding up-to-date epidemiologic insights during the pandemic. Participants were highly motivated, with regular feedback on interim results cite…
View article: High data retrieval rates with SwissPedData for paediatric traumatic brain injuries in children’s hospitals: a multicentre, point-prevalence study
High data retrieval rates with SwissPedData for paediatric traumatic brain injuries in children’s hospitals: a multicentre, point-prevalence study Open
STUDY AIMS: SwissPedNet aims to improve the quality of multicentre research through standardised documentation of routine healthcare data. Therefore, SwissPedData was developed as a set of defined common data elements to be documented in e…
View article: Did the COVID-19 pandemic impact paediatric health service utilisation in Switzerland? Interrupted time-series models of health insurance data
Did the COVID-19 pandemic impact paediatric health service utilisation in Switzerland? Interrupted time-series models of health insurance data Open
BACKGROUND: There is a scarcity of studies that examined the impact of the COVID-19 pandemic on different primary paediatric health services beyond the first pandemic year and with longitudinal analytical approaches. Concerning Switzerland…
View article: Adverse events among early caregivers' COVID-19 vaccination correlated inversely with intention to vaccinate their children
Adverse events among early caregivers' COVID-19 vaccination correlated inversely with intention to vaccinate their children Open
Side effects experienced by caregivers are associated with their intention to vaccinate their children. Building of trust in vaccines, including communicating risks and benefits in the context of caregiver's experience, is important and ma…
View article: How are fast tracks organized in adult and pediatric emergency departments in Switzerland? A cross-sectional survey
How are fast tracks organized in adult and pediatric emergency departments in Switzerland? A cross-sectional survey Open
View article: IL6 in Combination with Either NfL, NTproBNP, or GFAP Can Safely Rule Out Intracranial Injuries in Children with Mild Traumatic Brain Injury
IL6 in Combination with Either NfL, NTproBNP, or GFAP Can Safely Rule Out Intracranial Injuries in Children with Mild Traumatic Brain Injury Open
Background: Mild traumatic brain injury (mTBI) in children is a public health concern resulting in one of the main causes of pediatric emergency department (PED) visits. However, the acute care of mTBI patients remains challenging due to t…
View article: Evaluating NfL and NTproBNP as predictive biomarkers of intracranial injuries after mild traumatic brain injury in children presenting to emergency departments
Evaluating NfL and NTproBNP as predictive biomarkers of intracranial injuries after mild traumatic brain injury in children presenting to emergency departments Open
Objective Blood-biomarkers have the potential to aid clinicians in pediatric emergency departments (PED) in managing children with mild traumatic brain injury (mTBI) acutely. However, studies focusing on pediatric populations remain limite…
View article: Caregivers Reported Post Covid-19 Vaccine Adverse Events and Intention to Vaccinate Their Children Against Covid-19
Caregivers Reported Post Covid-19 Vaccine Adverse Events and Intention to Vaccinate Their Children Against Covid-19 Open
View article: Collecting data in pediatric outpatient settings during the SARS-CoV-2 pandemic: motivators and hurdles for a research network of primary care providers.
Collecting data in pediatric outpatient settings during the SARS-CoV-2 pandemic: motivators and hurdles for a research network of primary care providers. Open
View article: Clinical characteristics and serological profiles of Lyme disease in children: a 15-year retrospective cohort study in Switzerland
Clinical characteristics and serological profiles of Lyme disease in children: a 15-year retrospective cohort study in Switzerland Open
View article: Paediatric rotations in undergraduate medical education in Switzerland: Meeting students’ expectations and the goals of the competency-based learning catalogue PROFILES
Paediatric rotations in undergraduate medical education in Switzerland: Meeting students’ expectations and the goals of the competency-based learning catalogue PROFILES Open
Introduction: The competency-based catalogue of learning objectives “Principal Relevant Objectives and Framework for Integrative Learning and Education in Switzerland” (PROFILES) based on Entrustable Professional Activities (EPAs) was newl…
View article: Buddy taping after reduction of displaced extra-articular phalangeal finger fractures in children: a randomized controlled trial
Buddy taping after reduction of displaced extra-articular phalangeal finger fractures in children: a randomized controlled trial Open
In this randomized controlled trial, we assessed the non-inferiority of buddy taping to splinting after reduction of displaced extra-articular proximal and middle phalangeal finger fractures in children. The primary outcome was the rate of…
View article: A randomized controlled non-inferiority trial of placebo versus macrolide antibiotics for Mycoplasma pneumoniae infection in children with community-acquired pneumonia: trial protocol for the MYTHIC Study
A randomized controlled non-inferiority trial of placebo versus macrolide antibiotics for Mycoplasma pneumoniae infection in children with community-acquired pneumonia: trial protocol for the MYTHIC Study Open
ClinicalTrials.gov, NCT06325293. Registered on 24 April 2024.
View article: Assessing guideline adherence and child abuse evaluation in infants with fractures: a retrospective quality control study
Assessing guideline adherence and child abuse evaluation in infants with fractures: a retrospective quality control study Open
AIMS OF THE STUDY: To standardise the assessment of infants with fractures at University Children’s Hospital Zurich, a guideline was implemented in February 2021. The aim of this study was to assess adherence to this guideline and to asses…
View article: Diagnostic potential of IL6 and other blood-based inflammatory biomarkers in mild traumatic brain injury among children
Diagnostic potential of IL6 and other blood-based inflammatory biomarkers in mild traumatic brain injury among children Open
Objectives Inflammatory biomarkers, as indicators of biological states, provide a valuable approach for accurate and reproducible measurements, crucial for the effective management of mild traumatic brain injury (mTBI) in pediatric patient…
View article: Clusterin can mediate apoptosis-induced molecular mechanisms in immune thrombocytopenia
Clusterin can mediate apoptosis-induced molecular mechanisms in immune thrombocytopenia Open
Abnormalities in the apoptosis pathway have been implicated into the pathogenesis of various autoimmune diseases, including immune thrombocytopenia (ITP). Our data suggest that mechanisms associated with impaired clusterin-mediated apoptos…
View article: The effect of the COVID-19 pandemic on pediatric emergency department utilization in three regions in Switzerland
The effect of the COVID-19 pandemic on pediatric emergency department utilization in three regions in Switzerland Open
View article: Management of Pediatric Mild Traumatic Brain Injury Patients: S100b, Glial Fibrillary Acidic Protein, and Heart Fatty-Acid-Binding Protein Promising Biomarkers
Management of Pediatric Mild Traumatic Brain Injury Patients: S100b, Glial Fibrillary Acidic Protein, and Heart Fatty-Acid-Binding Protein Promising Biomarkers Open
Children are highly vulnerable to mild traumatic brain injury (mTBI). Blood biomarkers can help in their management. This study evaluated the performances of biomarkers, in discriminating between children with mTBI who had intracranial inj…
View article: Notfallmedizin: «Weniger ist mehr» – Verbesserung in der Behandlung von Patient:innen in pädiatrischen Notfallstationen
Notfallmedizin: «Weniger ist mehr» – Verbesserung in der Behandlung von Patient:innen in pädiatrischen Notfallstationen Open
Das Fachgebiet der pädiatrischen Notfallmedizin hat sich in den letzten Jahrzehnten kontinuierlich weiterentwickelt und seit 2014 existiert der Schwerpunkt Kindernotfallmedizin innerhalb der Fachgesellschaften für Kinder- und Jugendmedizin…
View article: Artificial intelligence-based detection of paediatric appendicular skeletal fractures: performance and limitations for common fracture types and locations
Artificial intelligence-based detection of paediatric appendicular skeletal fractures: performance and limitations for common fracture types and locations Open
Background Research into artificial intelligence (AI)-based fracture detection in children is scarce and has disregarded the detection of indirect fracture signs and dislocations. Objective To assess the diagnostic accuracy of an existing …
View article: Cardiac assessment and inflammatory markers in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV2 (PIMS-TS) treated with methylprednisolone versus intravenous immunoglobulins: 6-month follow-up outcomes of the randomised controlled Swissped RECOVERY trial
Cardiac assessment and inflammatory markers in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV2 (PIMS-TS) treated with methylprednisolone versus intravenous immunoglobulins: 6-month follow-up outcomes of the randomised controlled Swissped RECOVERY trial Open
View article: Analytical description of adolescent binge drinking patients
Analytical description of adolescent binge drinking patients Open