Michelle Willson
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View article: Intravital imaging of three different microvascular beds in SARS-CoV-2–infected mice
Intravital imaging of three different microvascular beds in SARS-CoV-2–infected mice Open
Severe acute respiratory syndrome coronavirus–2 (SARS-CoV-2) enters the respiratory tract, where it infects the alveoli epithelial lining. However, patients have sequelae that extend well beyond the alveoli into the pulmonary vasculature a…
View article: P-Selectin promotes SARS-CoV-2 interactions with platelets and the endothelium
P-Selectin promotes SARS-CoV-2 interactions with platelets and the endothelium Open
COVID-19 causes a clinical spectrum of acute and chronic illness and host / virus interactions are not completely understood 1,2 . To identify host factors that can influence SARS-CoV-2 infection, we screened the human genome for genes tha…
View article: Paracoccidioides brasiliensis Releases a DNase-Like Protein That Degrades NETs and Allows for Fungal Escape
Paracoccidioides brasiliensis Releases a DNase-Like Protein That Degrades NETs and Allows for Fungal Escape Open
Paracoccidioidomycosis is a systemic fungal disease, considered endemic in Latin America. Its etiological agents, fungi of the Paracoccidioides complex, have restricted geographic habitat, conidia as infecting form, and thermo-dimorphic ch…
View article: Bispecific antibody targets multiple Pseudomonas aeruginosa evasion mechanisms in the lung vasculature
Bispecific antibody targets multiple Pseudomonas aeruginosa evasion mechanisms in the lung vasculature Open
Pseudomonas aeruginosa is a major cause of severe infections that lead to bacteremia and high patient mortality. P. aeruginosa has evolved numerous evasion and subversion mechanisms that work in concert to overcome immune recognition and e…