Micky Karsten
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View article: Cardiac impact of dapagliflozin in advanced chronic kidney disease: rationale and design of the Renal Lifecycle Trial cardiac imaging sub-studies
Cardiac impact of dapagliflozin in advanced chronic kidney disease: rationale and design of the Renal Lifecycle Trial cardiac imaging sub-studies Open
Background Patients with chronic kidney disease (CKD) are frequently hospitalized for heart failure. Sodium-glucose co-transporter 2 (SGLT2)-inhibitors improve cardiorenal outcomes in CKD and heart failure, at least in estimated glomerular…
View article: #619 Natriuretic response to an acute oral potassium load in healthy individuals and patients with chronic kidney disease
#619 Natriuretic response to an acute oral potassium load in healthy individuals and patients with chronic kidney disease Open
Background and Aims The health benefits of dietary potassium have been linked to potassium-induced natriuresis. However, it is unknown whether potassium loading in patients with chronic kidney disease (CKD) induces natriuresis and to which…
#957 The immunometabolic profile of human peritoneal macrophages during peritoneal dialysis and its relation to systemic cardiovascular effects Open
Background and Aims Patients with end-stage kidney disease (ESKD) treated with peritoneal dialysis (PD) exhibit a high risk of heart failure (HF). This largely concerns HF with a preserved ejection fraction (HFpEF). Uremic toxins, oxidativ…
Kaliuresis and Intracellular Uptake of Potassium with Potassium Citrate and Potassium Chloride Supplements Open
Background A potassium replete diet is associated with lower cardiovascular risk but may increase the risk of hyperkalemia, particularly in people using renin-angiotensin-aldosterone system inhibitors. We investigated whether intracellular…
#4454 PERITONEAL DIALYSIS (PD) EFFLUENT DERIVED EXTACELLULAR VESICLES TO ESTABLISH PD-INDUCED PERITONEAL ALTERATIONS Open
Background and Aims Peritoneal dialysis (PD) is a life-saving kidney replacement treatment in patients with end-stage kidney disease (ESKD). Yet, long-term exposure of the peritoneal membrane to glucose and its degradation products results…