Øivind Midttun
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View article: Association Between Dietary Intake and Blood Concentrations of One-Carbon-Metabolism-Related Nutrients in European Prospective Investigation into Cancer and Nutrition
Association Between Dietary Intake and Blood Concentrations of One-Carbon-Metabolism-Related Nutrients in European Prospective Investigation into Cancer and Nutrition Open
Background/Objectives: We examined the association between dietary intake and blood concentrations of one-carbon metabolism (OCM)-related nutrients in the European Prospective Investigation into Cancer and Nutrition (EPIC). Methods: Blood …
View article: Plasma levels of immune system activation markers Neopterin and Kynurenine-to-Tryptophan Ratio, and oral health among community-dwelling adults in Norway: a population-based, cohort study
Plasma levels of immune system activation markers Neopterin and Kynurenine-to-Tryptophan Ratio, and oral health among community-dwelling adults in Norway: a population-based, cohort study Open
Objective: Periodontitis is a condition characterised by inflammation. Neopterin and kynurenine-to-tryptophan ratio (KTR) are markers of immune system activation in response to inflammation whose elevated levels are linked to higher incide…
View article: Supplementary Tables 1 and 2 from Biomarkers Related to One-Carbon Metabolism as Potential Risk Factors for Distal Colorectal Adenomas
Supplementary Tables 1 and 2 from Biomarkers Related to One-Carbon Metabolism as Potential Risk Factors for Distal Colorectal Adenomas Open
Supplementary Tables 1 and 2 from Biomarkers Related to One-Carbon Metabolism as Potential Risk Factors for Distal Colorectal Adenomas
View article: Data from Genetic Polymorphisms in 15q25 and 19q13 Loci, Cotinine Levels, and Risk of Lung Cancer in EPIC
Data from Genetic Polymorphisms in 15q25 and 19q13 Loci, Cotinine Levels, and Risk of Lung Cancer in EPIC Open
Backgrounds: Multiple polymorphisms affecting smoking behavior have been identified through genome-wide association studies. Circulating levels of the nicotine metabolite cotinine is a marker of recent smoking exposure. Hence, genetic vari…
View article: Supplementary Figure 1 caption from Circulating 25-Hydroxyvitamin D<sub>3</sub> and Survival after Diagnosis with Kidney Cancer
Supplementary Figure 1 caption from Circulating 25-Hydroxyvitamin D<sub>3</sub> and Survival after Diagnosis with Kidney Cancer Open
Supplementary Figure 1 caption
View article: Data from Circulating Biomarkers of Tryptophan and the Kynurenine Pathway and Lung Cancer Risk
Data from Circulating Biomarkers of Tryptophan and the Kynurenine Pathway and Lung Cancer Risk Open
Background: Imbalances in tryptophan metabolism have been linked to cancer-related immune escape and implicated in several cancers, including lung cancer.Methods: We conducted a nested case–control study within the European Prospective Inv…
View article: Supplementary Tables 1 and 2 from Biomarkers Related to One-Carbon Metabolism as Potential Risk Factors for Distal Colorectal Adenomas
Supplementary Tables 1 and 2 from Biomarkers Related to One-Carbon Metabolism as Potential Risk Factors for Distal Colorectal Adenomas Open
Supplementary Tables 1 and 2 from Biomarkers Related to One-Carbon Metabolism as Potential Risk Factors for Distal Colorectal Adenomas
View article: Supplementary Figure 2 from Maternal Smoking and DNA Methylation in Newborns: <i>In Utero</i> Effect or Epigenetic Inheritance?
Supplementary Figure 2 from Maternal Smoking and DNA Methylation in Newborns: <i>In Utero</i> Effect or Epigenetic Inheritance? Open
PDF - 80K, Association between the timing of mother smoking (before and during pregnancy) and DNA methylation at 26 CpGs of interest. Each point represents the association for each CpG in each smoking category. *Significance threshold p<0.…
View article: Data from Circulating Biomarkers of Tryptophan and the Kynurenine Pathway and Lung Cancer Risk
Data from Circulating Biomarkers of Tryptophan and the Kynurenine Pathway and Lung Cancer Risk Open
Background: Imbalances in tryptophan metabolism have been linked to cancer-related immune escape and implicated in several cancers, including lung cancer.Methods: We conducted a nested case–control study within the European Prospective Inv…
View article: Supplementary Figure 4 from Maternal Smoking and DNA Methylation in Newborns: <i>In Utero</i> Effect or Epigenetic Inheritance?
Supplementary Figure 4 from Maternal Smoking and DNA Methylation in Newborns: <i>In Utero</i> Effect or Epigenetic Inheritance? Open
PDF - 225K, Evaluation of the additional effect of grandmother smoking on DNA methylation at the 26 CpGs of interest, given the mother smoked in her pregnancy. Each point represents the association for each CpG in each category. *Significa…
View article: Supplementary Figure 1 from Maternal Smoking and DNA Methylation in Newborns: <i>In Utero</i> Effect or Epigenetic Inheritance?
Supplementary Figure 1 from Maternal Smoking and DNA Methylation in Newborns: <i>In Utero</i> Effect or Epigenetic Inheritance? Open
PDF - 2930K, Timeline describing the collection of smoking information and methylation measurements for the study participants.
View article: Supplementary Figure 2 from Circulating Biomarkers of Tryptophan and the Kynurenine Pathway and Lung Cancer Risk
Supplementary Figure 2 from Circulating Biomarkers of Tryptophan and the Kynurenine Pathway and Lung Cancer Risk Open
PDF file - 90K, Linear regression for circulating Tryptophan, Kynurenine and Kynurenine/tryptophan ratio in relation to food groups, lifestyle factors and other circulating biomarkers of a nested case-control study in the EPIC cohort. Rati…
View article: Supplementary Figure 5 from Circulating Biomarkers of Tryptophan and the Kynurenine Pathway and Lung Cancer Risk
Supplementary Figure 5 from Circulating Biomarkers of Tryptophan and the Kynurenine Pathway and Lung Cancer Risk Open
PDF file - 113K, Odds ratios with 95% Confidence Intervals (CI) of lung cancer for circulating levels of Tryptophan, Kynurenine and Kynurenine/Tryptophan ratio by smoking status. P for trend were assessed by the base 2 logarithm of the cir…
View article: Supplementary Figure 4 from Maternal Smoking and DNA Methylation in Newborns: <i>In Utero</i> Effect or Epigenetic Inheritance?
Supplementary Figure 4 from Maternal Smoking and DNA Methylation in Newborns: <i>In Utero</i> Effect or Epigenetic Inheritance? Open
PDF - 225K, Evaluation of the additional effect of grandmother smoking on DNA methylation at the 26 CpGs of interest, given the mother smoked in her pregnancy. Each point represents the association for each CpG in each category. *Significa…
View article: Data from Circulating 25-Hydroxyvitamin D<sub>3</sub> and Survival after Diagnosis with Kidney Cancer
Data from Circulating 25-Hydroxyvitamin D<sub>3</sub> and Survival after Diagnosis with Kidney Cancer Open
Prospective cohort studies have provided some evidence that circulating vitamin D is associated with risk of, and survival from, renal cell carcinoma (RCC), but it is unclear whether concentrations of vitamin D at the time of diagnosis of …
View article: Supplementary Figure 1 caption from Circulating 25-Hydroxyvitamin D<sub>3</sub> and Survival after Diagnosis with Kidney Cancer
Supplementary Figure 1 caption from Circulating 25-Hydroxyvitamin D<sub>3</sub> and Survival after Diagnosis with Kidney Cancer Open
Supplementary Figure 1 caption
View article: Supplementary Methods from Genetic Polymorphisms in 15q25 and 19q13 Loci, Cotinine Levels, and Risk of Lung Cancer in EPIC
Supplementary Methods from Genetic Polymorphisms in 15q25 and 19q13 Loci, Cotinine Levels, and Risk of Lung Cancer in EPIC Open
PDF file - 82K
View article: Supplementary Figure 2 from Maternal Smoking and DNA Methylation in Newborns: <i>In Utero</i> Effect or Epigenetic Inheritance?
Supplementary Figure 2 from Maternal Smoking and DNA Methylation in Newborns: <i>In Utero</i> Effect or Epigenetic Inheritance? Open
PDF - 80K, Association between the timing of mother smoking (before and during pregnancy) and DNA methylation at 26 CpGs of interest. Each point represents the association for each CpG in each smoking category. *Significance threshold p<0.…
View article: Supplementary Figure 1 from Circulating 25-Hydroxyvitamin D<sub>3</sub> and Survival after Diagnosis with Kidney Cancer
Supplementary Figure 1 from Circulating 25-Hydroxyvitamin D<sub>3</sub> and Survival after Diagnosis with Kidney Cancer Open
Supplementary Figure 1. Hazard ratios (HR) and 95% confidence intervals (CI) for a doubling in season-adjusted 25(OH)D3 concentration by potential effect modifiers.
View article: Supplementary Figure 3 from Maternal Smoking and DNA Methylation in Newborns: <i>In Utero</i> Effect or Epigenetic Inheritance?
Supplementary Figure 3 from Maternal Smoking and DNA Methylation in Newborns: <i>In Utero</i> Effect or Epigenetic Inheritance? Open
PDF - 16K, Association between the combined mother and grandmother smoking categories and DNA methylation at 26 CpGs of interest. Each point represents the association for each CpG in each smoking category. *Significance threshold p<0.0019…
View article: Supplementary Figure 3 from Circulating Biomarkers of Tryptophan and the Kynurenine Pathway and Lung Cancer Risk
Supplementary Figure 3 from Circulating Biomarkers of Tryptophan and the Kynurenine Pathway and Lung Cancer Risk Open
PDF file - 98K, Odds ratios with 95% Confidence Intervals (CI) of lung cancer for circulating levels of Kynurenic acid, 3-Hydroxykynurenine, Anthralinic acid, Xanthurenic acid, 3-Hydroxyantranilic acid and Neopterine. P for trend were asse…
View article: Supplementary Methods from Genetic Polymorphisms in 15q25 and 19q13 Loci, Cotinine Levels, and Risk of Lung Cancer in EPIC
Supplementary Methods from Genetic Polymorphisms in 15q25 and 19q13 Loci, Cotinine Levels, and Risk of Lung Cancer in EPIC Open
PDF file - 82K
View article: Data from Biomarkers Related to One-Carbon Metabolism as Potential Risk Factors for Distal Colorectal Adenomas
Data from Biomarkers Related to One-Carbon Metabolism as Potential Risk Factors for Distal Colorectal Adenomas Open
Background: Efficient one-carbon metabolism, which requires adequate supply of methyl group donors and B-vitamins, may protect against colorectal carcinogenesis. However, plasma folate and vitamins B2 and B12 have inconsistently been assoc…
View article: Supplementary Figure 4 from Circulating Biomarkers of Tryptophan and the Kynurenine Pathway and Lung Cancer Risk
Supplementary Figure 4 from Circulating Biomarkers of Tryptophan and the Kynurenine Pathway and Lung Cancer Risk Open
PDF file - 100K, Odds Ratios with 95% Confidence Intervals (CI) of Lung Cancer for circulating levels of Tryptophan, Kynurenine and Kynurenine/Tryptophan ratio by histological type. P for trend were assessed by the base 2 logarithm of the …
View article: Supplementary Figure 1 from Circulating 25-Hydroxyvitamin D<sub>3</sub> and Survival after Diagnosis with Kidney Cancer
Supplementary Figure 1 from Circulating 25-Hydroxyvitamin D<sub>3</sub> and Survival after Diagnosis with Kidney Cancer Open
Supplementary Figure 1. Hazard ratios (HR) and 95% confidence intervals (CI) for a doubling in season-adjusted 25(OH)D3 concentration by potential effect modifiers.
View article: Data from Maternal Smoking and DNA Methylation in Newborns: <i>In Utero</i> Effect or Epigenetic Inheritance?
Data from Maternal Smoking and DNA Methylation in Newborns: <i>In Utero</i> Effect or Epigenetic Inheritance? Open
Background: Maternal smoking in pregnancy is associated with adverse health outcomes in children, including cancers; underlying mechanisms may include epigenetic modifications. Using Illumina's 450K array, we previously identified differen…
View article: Data from Circulating 25-Hydroxyvitamin D<sub>3</sub> and Survival after Diagnosis with Kidney Cancer
Data from Circulating 25-Hydroxyvitamin D<sub>3</sub> and Survival after Diagnosis with Kidney Cancer Open
Prospective cohort studies have provided some evidence that circulating vitamin D is associated with risk of, and survival from, renal cell carcinoma (RCC), but it is unclear whether concentrations of vitamin D at the time of diagnosis of …
View article: Supplementary Figure 5 from Circulating Biomarkers of Tryptophan and the Kynurenine Pathway and Lung Cancer Risk
Supplementary Figure 5 from Circulating Biomarkers of Tryptophan and the Kynurenine Pathway and Lung Cancer Risk Open
PDF file - 113K, Odds ratios with 95% Confidence Intervals (CI) of lung cancer for circulating levels of Tryptophan, Kynurenine and Kynurenine/Tryptophan ratio by smoking status. P for trend were assessed by the base 2 logarithm of the cir…