Miguel A. Medina-Serpas
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View article: Spatial transcriptomics from pancreas and local draining lymph node tissue reveals a lymphotoxin-β signature in human type 1 diabetes
Spatial transcriptomics from pancreas and local draining lymph node tissue reveals a lymphotoxin-β signature in human type 1 diabetes Open
SUMMARY This study explores the inflammatory response observed in pancreata and pancreatic lymph node (pLN) samples obtained throughout the natural history of type 1 diabetes (T1D) including non-diabetic individuals and non-diabetic autoan…
View article: A growth factor–expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15
A growth factor–expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15 Open
Muscle regeneration is the result of the concerted action of multiple cell types driven by the temporarily controlled phenotype switches of infiltrating monocyte–derived macrophages. Pro-inflammatory macrophages transition into a phenotype…