Mihaela Paula Toader
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View article: Multiple Basal Cell Carcinomas in a Long-Term Survivor of Childhood ALL and HSCT—A Call for Dermatologic Vigilance
Multiple Basal Cell Carcinomas in a Long-Term Survivor of Childhood ALL and HSCT—A Call for Dermatologic Vigilance Open
(1) Background: Cutaneous secondary malignant neoplasms are a growing survivorship burden after pediatric cancers and hematopoietic stem cell transplantation (HSCT), yet skin-focused surveillance remains inconsistently implemented. (2) Obj…
View article: Real-world outcomes with rituximab vs. conventional therapy in pemphigus vulgaris: a single-center Romanian cohort
Real-world outcomes with rituximab vs. conventional therapy in pemphigus vulgaris: a single-center Romanian cohort Open
Background Pemphigus vulgaris (PV) is a rare but potentially life-threatening autoimmune blistering disease. Rituximab has recently gained prominence as a first-line treatment for moderate-to-severe PV, yet real-world evidence from Eastern…
View article: The Inflammatory–Dysplastic Spectrum in Oral Lichen Planus: A Study on Six Immunohistochemical Markers
The Inflammatory–Dysplastic Spectrum in Oral Lichen Planus: A Study on Six Immunohistochemical Markers Open
Background/Objective: Oral lichen planus (OLP) is a chronic inflammatory, immune-mediated mucosal condition classified as a potentially malignant disorder due to its risk of progression to oral squamous cell carcinoma (OSCC). The molecular…
View article: Metastatic Head and Neck Non-Melanoma Skin Cancer: A Retrospective Analysis of Clinico-Pathologic Features and Reconstructive Approach
Metastatic Head and Neck Non-Melanoma Skin Cancer: A Retrospective Analysis of Clinico-Pathologic Features and Reconstructive Approach Open
Background/Objectives: Non-melanoma skin cancer (NMSC) is the most common malignancy globally, with cutaneous squamous cell carcinoma (cSCC) posing a significant risk of regional metastasis, especially in high-risk anatomical areas such as…
View article: From Lasers to Longevity: Exploring Energy-Based Devices as Senotherapeutic Tools in Dermatology
From Lasers to Longevity: Exploring Energy-Based Devices as Senotherapeutic Tools in Dermatology Open
Background: Cutaneous aging is a multifactorial process, increasingly understood through the lens of cellular senescence, a state of stable cell cycle arrest accompanied by a pro-inflammatory secretory phenotype that disrupts tissue homeos…
View article: Cardiometabolic Comorbidities of Lichen Planus—A Cross-Sectional Comparative Study
Cardiometabolic Comorbidities of Lichen Planus—A Cross-Sectional Comparative Study Open
Background/Objectives: Cardiovascular disease (CVD) remains one of the leading causes of death worldwide, with several well-established risk factors. Among dermatological conditions, psoriasis is a well-known contributor to cardiometabolic…
View article: Immunohistochemical Assessment of Maspin, β-Catenin, and MMP-14 in Oral Potentially Malignant Lesions and Oral Squamous Cell Carcinoma: A Retrospective Observational Study
Immunohistochemical Assessment of Maspin, β-Catenin, and MMP-14 in Oral Potentially Malignant Lesions and Oral Squamous Cell Carcinoma: A Retrospective Observational Study Open
Background and Objectives: Oral cancer remains a critical global health burden. Oral potentially malignant disorders (OMPDs) such as leukoplakia and oral lichen planus can precede oral squamous cell carcinoma (OSCC). Inflammation, tissue r…
View article: Diagnostic and Therapeutic Challenges in Psoriasis–Atopic Dermatitis Overlap: A Retrospective Observational Cohort Study
Diagnostic and Therapeutic Challenges in Psoriasis–Atopic Dermatitis Overlap: A Retrospective Observational Cohort Study Open
Background and Objectives: Psoriasis and atopic dermatitis (AD) are immune-mediated inflammatory diseases traditionally viewed as distinct. However, a subset of patients may present with overlapping features, leading to diagnostic and ther…
View article: Prevalence of Psychiatric and Addictive Disorders in Patients with Psoriasis: A Cross-Sectional Study
Prevalence of Psychiatric and Addictive Disorders in Patients with Psoriasis: A Cross-Sectional Study Open
Background/Objectives: Psoriasis is a chronic inflammatory skin disease increasingly linked to psychiatric and behavioral comorbidities, including depression, anxiety, and substance use disorders. Shared inflammatory pathways, including el…
View article: Mucoscopic Features of Oral Lichen Planus: A Retrospective Comparative Study with Inflammatory Mimickers
Mucoscopic Features of Oral Lichen Planus: A Retrospective Comparative Study with Inflammatory Mimickers Open
Background/Objectives: Oral lichen planus (OLP) is a chronic inflammatory mucocutaneous disorder with a recognized potential for malignant transformation. While histopathological examination remains the diagnostic gold standard, mucoscopy …
View article: Dual Relief: How Atopic Dermatitis Treatments Affect Alopecia Areata—A Small Retrospective Cohort Study
Dual Relief: How Atopic Dermatitis Treatments Affect Alopecia Areata—A Small Retrospective Cohort Study Open
Background/Objectives: Atopic dermatitis (AD) and alopecia areata (AA) frequently coexist due to shared immune-mediated mechanisms. Treatments targeting AD, including Janus kinase (JAK) inhibitors and dupilumab, may impact AA outcomes in u…
View article: Immunohistochemical Expression of Differentiated Embryonic Chondrocyte 1 and Cluster of Differentiation 44 in Oral Potentially Malignant Disorders
Immunohistochemical Expression of Differentiated Embryonic Chondrocyte 1 and Cluster of Differentiation 44 in Oral Potentially Malignant Disorders Open
Background and Objectives: Oral cancer remains a critical global health concern, with oral squamous cell carcinoma (OSCC) being the most prevalent form. Oral potentially malignant disorders (OPMDs), such as oral leukoplakia (OLK), oral lic…
View article: Dietary Habits, Obesity, and Bariatric Surgery: A Review of Impact and Interventions
Dietary Habits, Obesity, and Bariatric Surgery: A Review of Impact and Interventions Open
Eating behavior encompasses the psychological, physiological, and environmental factors influencing food intake. Dysregulation in eating behavior, such as emotional eating, binge eating, or loss of satiety signals, contributes to excessive…
View article: Cardiovascular Profile and Cardiovascular Imaging After Bariatric Surgery: A Narrative Review
Cardiovascular Profile and Cardiovascular Imaging After Bariatric Surgery: A Narrative Review Open
Background and Objectives: Up until now, behavioral interventions and pharmacological therapies were the main approach available for the management of obesity. Diet and exercise, when used as a singular therapeutic method, are inadequate f…
View article: HYPERSENSITIVITY REACTIONS AFFECTING ORAL MUCOSA: DIAGNOSTIC AND THERAPEUTIC CHALLENGES
HYPERSENSITIVITY REACTIONS AFFECTING ORAL MUCOSA: DIAGNOSTIC AND THERAPEUTIC CHALLENGES Open
Hypersensitivity reactions affecting the oral mucosa present a significant clinical challenge due to their diverse manifestations and the wide range of potential allergens involved. This article explores the types of allergic reactions com…
View article: Integrative Approaches for the Diagnosis and Management of Erosive Oral Lichen Planus
Integrative Approaches for the Diagnosis and Management of Erosive Oral Lichen Planus Open
Erosive oral lichen planus (EOLP) represents a significant challenge in dental and medical management due to its chronic inflammatory nature, painful symptoms, and impact on quality of life. This study aims to evaluate the current diagnost…
View article: Psoriasis and depression: Elucidating the molecular interplay
Psoriasis and depression: Elucidating the molecular interplay Open
Psoriasis and depression are prevalent and often co-occurring disorders, yet the molecular basis of their association remains inadequately understood.This review aims to synthesize current knowledge on the molecular links between psoriasis…
View article: POTENTIALLY MALIGNANT LESIONS IN THE ORAL CAVITY: A RETROSPECTIVE ANALYSIS
POTENTIALLY MALIGNANT LESIONS IN THE ORAL CAVITY: A RETROSPECTIVE ANALYSIS Open
The study aimed to present the characteristics of the three most prevalent oral potentially malignant disorders, leukoplakia, oral lichen planus (OLP), and actinic cheilitis, using data from 62 patients collected at the “Sfântul Spiridon” …
View article: ORAL PATHOLOGY IN THE CONTEXT OF MENOPAUSE IN WOMEN
ORAL PATHOLOGY IN THE CONTEXT OF MENOPAUSE IN WOMEN Open
Menopause is a non-pathological change which involve the permanent cessation of menstruation for at least 12 months and occurs in women with an average age of 51 years in the context of non-pathological estrogen deficiency. The effects of …
View article: EMERGING USE OF JANUS KINASE INHIBITORS FOR ORAL LICHEN PLANUS
EMERGING USE OF JANUS KINASE INHIBITORS FOR ORAL LICHEN PLANUS Open
Oral lichen planus (OLP) is a chronic inflammatory condition that poses significant therapeutic challenges. Emerging evidence suggests that topical Janus Kinase (JAK) inhibitors could represent a novel treatment paradigm for OLP. This revi…
View article: SALIVA AS A DIAGNOSTIC TOOL: INSIGHTS INTO ORAL CANCER BIOMARKERS
SALIVA AS A DIAGNOSTIC TOOL: INSIGHTS INTO ORAL CANCER BIOMARKERS Open
This narrative review highlights the emerging role of salivary markers in the detection of oral cancer. Saliva contains diverse biomolecules that can provide valuable information on physiological and pathological processes in the body, inc…
View article: An Overview of Panniculitis – A Diagnostic Challenge for Dermatologists and Pathologists
An Overview of Panniculitis – A Diagnostic Challenge for Dermatologists and Pathologists Open
": The term ""panniculitis"" refers to a heterogeneous group of conditions that involve inflammation of the subcutaneous cellular tissue. Although there is no universally accepted classification of panniculitis, to facilitate the diagnosis…
View article: Differences and Similarities in Epidemiology and Risk Factors for Cutaneous and Uveal Melanoma
Differences and Similarities in Epidemiology and Risk Factors for Cutaneous and Uveal Melanoma Open
Both cutaneous melanoma (CM) and uveal melanoma (UM) represent important causes of morbidity and mortality. In this review, we evaluate the available knowledge on the differences and similarities between cutaneous melanoma and uveal melano…
View article: Sentinel Lymph Node Biopsy in Cutaneous Melanoma, a Clinical Point of View
Sentinel Lymph Node Biopsy in Cutaneous Melanoma, a Clinical Point of View Open
Sentinel lymph node biopsy (SLNB) is a surgical procedure that has been used in patients with cutaneous melanoma for nearly 30 years. It is used for both staging and regional disease control with minimum morbidity, as proven by numerous wo…
View article: Desquamative Gingivitis in the Context of Autoimmune Bullous Dermatoses and Lichen Planus—Challenges in the Diagnosis and Treatment
Desquamative Gingivitis in the Context of Autoimmune Bullous Dermatoses and Lichen Planus—Challenges in the Diagnosis and Treatment Open
Desquamative gingivitis (DG) is a clinical term that describes erythema, desquamation and erosions of the gingiva, of various etiologies. Although the clinical aspect is not specific for a certain disease, an accurate diagnosis of the unde…
View article: Schwannoma of the Upper Limb: Retrospective Study of a Rare Tumor with Uncommon Locations
Schwannoma of the Upper Limb: Retrospective Study of a Rare Tumor with Uncommon Locations Open
Background: Although schwannoma (neurilemmoma) is the most common tumor of the peripheral nerve, its low incidence, slow growth and vague symptoms often lead to misdiagnosis or delayed diagnosis. The aim of the study is to present a series…
View article: Phototherapy in dermatological maladies (Review)
Phototherapy in dermatological maladies (Review) Open
Since the introduction of modern phototherapy in 1903 by Nobel Prize-winner Niels Ryberg Finsen, the usage of this therapy in the medical field has grown, techniques have been refined and developed, and it has gained widespread acceptance.…
View article: Mucocutaneous lesions associated with SARS‑CoV‑2 infection (Review)
Mucocutaneous lesions associated with SARS‑CoV‑2 infection (Review) Open
The ongoing COVID-19 pandemic, declared by the World Health Organisation in March 2020, with the emergence of new, possibly more contagious and more virulent strains, remains a research subject, with the complex systemic involvement better…
View article: Update on the etiopathogenesis of psoriasis (Review)
Update on the etiopathogenesis of psoriasis (Review) Open
Psoriasis is one of the most common immune-mediated chronic inflammatory skin disorders, involving hyperproliferative keratinocytes and infiltration of T cells, dendritic cells, macrophages, and neutrophils. Multiple factors appear to play…
View article: Metabolic comorbidities of psoriasis (Review)
Metabolic comorbidities of psoriasis (Review) Open
Psoriasis is a chronic inflammatory and immune-mediated condition, which is no longer considered as being limited to the skin, but may affect the entire body. Epidemiological studies have shown that certain disorders, including obesity, di…