Mika Helmiö
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View article: Intraoperative complications during gastrectomy for gastric cancer – incidence, treatment, and effect on postoperative complications and survival in a population-based nationwide study
Intraoperative complications during gastrectomy for gastric cancer – incidence, treatment, and effect on postoperative complications and survival in a population-based nationwide study Open
Purpose Studies reporting intraoperative complications during gastrectomy for gastric cancer or their effect on short- and long-term outcomes are rare. Our aim was to examine the effect of major intraoperative complications to incidence of…
View article: The Prognostic Role of Lymphadenectomy during Esophagectomy for Esophageal Cancer with Complete or Near-Complete Tumor Response after Neoadjuvant Therapy
The Prognostic Role of Lymphadenectomy during Esophagectomy for Esophageal Cancer with Complete or Near-Complete Tumor Response after Neoadjuvant Therapy Open
Background The prognostic role of lymphadenectomy during esophagectomy for esophageal cancer in complete responders to neoadjuvant therapy is uncertain. This study aimed to help clarify this question. Patients and Methods This was a bi-nat…
View article: Characterization of Visceral Adipose Tissue Proteome Reveals Metabolic Changes and Inflammatory Signatures in Severe Obesity
Characterization of Visceral Adipose Tissue Proteome Reveals Metabolic Changes and Inflammatory Signatures in Severe Obesity Open
Objective Severe obesity poses a major public health concern due to its links with cardiometabolic complications and mortality. Visceral adipose tissue (VAT) plays a key role in these processes through distinct molecular features. This stu…
View article: ASO Author Reflections: Neoadjuvant Treatment Does not Increase Postoperative Complications Compared with Upfront Surgery in Esophageal Cancer
ASO Author Reflections: Neoadjuvant Treatment Does not Increase Postoperative Complications Compared with Upfront Surgery in Esophageal Cancer Open
View article: Neoadjuvant Treatment and Postoperative Complications After Surgery for Esophageal Cancer: A Population-Based, Nationwide Study in Finland
Neoadjuvant Treatment and Postoperative Complications After Surgery for Esophageal Cancer: A Population-Based, Nationwide Study in Finland Open
Background The role of neoadjuvant treatment and its modalities in the risk of complications after esophagectomy in national practice is unclear. The aim of this study was to compare postoperative complications after neoadjuvant treatment …
View article: Nutritional deficiencies after sleeve gastrectomy and Roux-en-Y gastric bypass at 10 years: secondary analysis of the SLEEVEPASS randomized clinical trial
Nutritional deficiencies after sleeve gastrectomy and Roux-en-Y gastric bypass at 10 years: secondary analysis of the SLEEVEPASS randomized clinical trial Open
Background Long-term data on the prevalence of nutritional deficiencies after laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB) in RCTs are lacking. The aim of this study was to compare nutritional def…
View article: Comparing Gastrectomy Complications Consensus Group (GCCG) and Esophagectomy Complications Consensus Group (ECCG) Classifications in Reporting Postoperative Complications After Gastrectomy: A Population-Based Nationwide Study in Finland
Comparing Gastrectomy Complications Consensus Group (GCCG) and Esophagectomy Complications Consensus Group (ECCG) Classifications in Reporting Postoperative Complications After Gastrectomy: A Population-Based Nationwide Study in Finland Open
View article: Surgical complications after minimally invasive oesophagectomy compared to open oesophagectomy for oesophageal cancer: A population-based, nationwide study in Finland
Surgical complications after minimally invasive oesophagectomy compared to open oesophagectomy for oesophageal cancer: A population-based, nationwide study in Finland Open
This study suggests a significant reduction in various surgical complications in patients undergoing MIO compared to OO and that implementing MIO into nationwide practice can be done safely.
View article: Epidural analgesia during esophagectomy and esophageal cancer prognosis: A population‐based nationwide study in Finland
Epidural analgesia during esophagectomy and esophageal cancer prognosis: A population‐based nationwide study in Finland Open
Background The use of epidural analgesia has been proposed to improve the prognosis of esophageal cancer by attenuating the stress response and being less immunosuppressive than opioids. This study aims to evaluate the association, if any,…
View article: Incidence trends of surgical complications after oesophagectomy for oesophageal cancer: a population-based, nationwide cohort study in Finland over 30 years
Incidence trends of surgical complications after oesophagectomy for oesophageal cancer: a population-based, nationwide cohort study in Finland over 30 years Open
Background Knowledge on the incidence of surgical complications after oesophagectomy for oesophageal cancer in nationwide practice is scarce. The aim of this study was to assess complication trends after oesophagectomy in a nationwide, pop…
View article: Preoperative predictors of postoperative complications after gastrectomy for gastric cancer, a population-based study in Finland
Preoperative predictors of postoperative complications after gastrectomy for gastric cancer, a population-based study in Finland Open
Higher ASA-class, and advanced tumor stage were risk factors for major complications after gastrectomy for gastric cancer, while older age and distal tumor location seemed to be protective factors.
View article: Association of High-Sensitivity C-Reactive Protein (hs-CRP) with Weight Loss After Sleeve Gastrectomy and Roux-en-Y Gastric Bypass at 10 Years: A Secondary Analysis of the SLEEVEPASS Randomized Clinical Trial
Association of High-Sensitivity C-Reactive Protein (hs-CRP) with Weight Loss After Sleeve Gastrectomy and Roux-en-Y Gastric Bypass at 10 Years: A Secondary Analysis of the SLEEVEPASS Randomized Clinical Trial Open
View article: Impact of splenectomy on long-term outcomes after gastrectomy for gastric cancer: a population-based study
Impact of splenectomy on long-term outcomes after gastrectomy for gastric cancer: a population-based study Open
The OS was worst in patients who underwent gastrectomy with splenectomy due to oncologic reasons, highlighting the poor prognosis in patients with advanced gastric cancer. Splenectomy due to injury does not compromise the prognosis.
View article: Comparison of Postoperative Complications After Gastrectomy for Gastric Cancer with Antecolic Versus Retrocolic Reconstruction: A Population-Based Study
Comparison of Postoperative Complications After Gastrectomy for Gastric Cancer with Antecolic Versus Retrocolic Reconstruction: A Population-Based Study Open
View article: Postoperative delayed emptying after total, subtotal, or distal gastrectomy for gastric cancer: a population-based study
Postoperative delayed emptying after total, subtotal, or distal gastrectomy for gastric cancer: a population-based study Open
The extent of resection did not affect delayed emptying, whereas fewer postoperative complications were observed after subtotal or distal gastrectomy than after total gastrectomy.
View article: Stapled vs handsewn anastomosis and anastomotic leaks in gastric cancer surgery—a population-based nationwide study in Finland
Stapled vs handsewn anastomosis and anastomotic leaks in gastric cancer surgery—a population-based nationwide study in Finland Open
In this population-based nationwide study, anastomotic technique (stapled or handsewn) was not associated with anastomotic leaks in any, distal or total, gastrectomy.
View article: Postoperative Complications After Neoadjuvant Chemotherapy Versus Upfront Surgery in Gastric Adenocarcinoma: A Population-Based Nationwide Study in Finland
Postoperative Complications After Neoadjuvant Chemotherapy Versus Upfront Surgery in Gastric Adenocarcinoma: A Population-Based Nationwide Study in Finland Open
View article: Standardized Assessment of Metabolic Bariatric Surgery Outcomes
Standardized Assessment of Metabolic Bariatric Surgery Outcomes Open
Importance A standardized definition and reporting of metabolic bariatric surgery (MBS) outcomes is not available for actual clinical practice and science. Objective To assess the feasibility of using a clinically relevant and feasible MBS…
View article: Population-based nationwide incidence of complications after gastrectomy for gastric adenocarcinoma in Finland
Population-based nationwide incidence of complications after gastrectomy for gastric adenocarcinoma in Finland Open
Background The incidence of postoperative complications after gastrectomy for gastric cancer is not well known. More population-based studies using established complication classifications are needed for international comparison. The aim o…
View article: Preoperative Esophageal Stenting and 5-Year Survival in Patients Undergoing Esophagectomy for Esophageal Cancer: a Population-Based Nationwide Study from Finland
Preoperative Esophageal Stenting and 5-Year Survival in Patients Undergoing Esophagectomy for Esophageal Cancer: a Population-Based Nationwide Study from Finland Open
View article: Validation of the individualized metabolic surgery score for bariatric procedure selection in the merged data of two randomized clinical trials (SLEEVEPASS and SM-BOSS)
Validation of the individualized metabolic surgery score for bariatric procedure selection in the merged data of two randomized clinical trials (SLEEVEPASS and SM-BOSS) Open
In our study, remission rates of T2D were not statistically different after LSG and LRYGB among all patients and among patients with mild, moderate, and severe diabetes stratified by the IMS score. However, the study may be underpowered to…
View article: ASO Author Reflections: Similar Long-Term Survival After Transhiatal Compared to Transthoracic Esophagectomy
ASO Author Reflections: Similar Long-Term Survival After Transhiatal Compared to Transthoracic Esophagectomy Open
PASTTranshiatal esophagectomy (THE) and transthoracic esophagectomy (TTE) are valid surgical procedures for esophageal cancer.TTE allows for more extensive lymphadenectomy via thoracic dissection, while THE has been preferred in frail pati…
View article: Long-Term Survival After Transhiatal Versus Transthoracic Esophagectomy: A Population-Based Nationwide Study in Finland
Long-Term Survival After Transhiatal Versus Transthoracic Esophagectomy: A Population-Based Nationwide Study in Finland Open
Background No population-based studies comparing long-term survival after transhiatal esophagectomy (THE) and transthoracic esophagectomy (TTE) exist. This study aimed to compare the 5-year survival of esophageal cancer patients undergoing…
View article: Renal Sinus Fat Is Expanded in Patients with Obesity and/or Hypertension and Reduced by Bariatric Surgery Associated with Hypertension Remission
Renal Sinus Fat Is Expanded in Patients with Obesity and/or Hypertension and Reduced by Bariatric Surgery Associated with Hypertension Remission Open
Renal sinus fat is a fat depot at the renal hilum. Because of its location around the renal artery, vein, and lymphatic vessels, an expanded renal sinus fat mass may have hemodynamic and renal implications. We studied whether renal sinus f…
View article: Effect of Laparoscopic Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass on Weight Loss, Comorbidities, and Reflux at 10 Years in Adult Patients With Obesity
Effect of Laparoscopic Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass on Weight Loss, Comorbidities, and Reflux at 10 Years in Adult Patients With Obesity Open
ClinicalTrials.gov Identifier: NCT00793143.
View article: Preoperative hemoglobin count and prognosis of esophageal cancer, a population-based nationwide study in Finland
Preoperative hemoglobin count and prognosis of esophageal cancer, a population-based nationwide study in Finland Open
The prognostic value of preoperative hemoglobin in patients undergoing esophagectomy is unknown. The aim of this study was to examine whether preoperative hemoglobin is associated with prognosis in patients undergoing esophagectomy for can…
View article: Systemic cross-talk between brain, gut, and peripheral tissues in glucose homeostasis: effects of exercise training (CROSSYS). Exercise training intervention in monozygotic twins discordant for body weight
Systemic cross-talk between brain, gut, and peripheral tissues in glucose homeostasis: effects of exercise training (CROSSYS). Exercise training intervention in monozygotic twins discordant for body weight Open
View article: Effect of Laparoscopic Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass on Weight Loss and Quality of Life at 7 Years in Patients With Morbid Obesity
Effect of Laparoscopic Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass on Weight Loss and Quality of Life at 7 Years in Patients With Morbid Obesity Open
ClinicalTrials.gov Identifier: NCT00793143.
View article: Physical Activity Associates with Muscle Insulin Sensitivity Postbariatric Surgery
Physical Activity Associates with Muscle Insulin Sensitivity Postbariatric Surgery Open
Purpose Bariatric surgery is considered as an effective therapeutic strategy for weight loss in severe obesity. Remission of type 2 diabetes is often achieved after the surgery. We investigated whether increase in self-reported habitual ph…
View article: Effect of Laparoscopic Sleeve Gastrectomy vs Laparoscopic Roux-en-Y Gastric Bypass on Weight Loss at 5 Years Among Patients With Morbid Obesity
Effect of Laparoscopic Sleeve Gastrectomy vs Laparoscopic Roux-en-Y Gastric Bypass on Weight Loss at 5 Years Among Patients With Morbid Obesity Open
clinicaltrials.gov Identifier: NCT00793143.