Mikhail Bashkurov
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View article: Author Correction: Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility
Author Correction: Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility Open
View article: Identification of acquired Notch3 dependency in metastatic Head and Neck Cancer
Identification of acquired Notch3 dependency in metastatic Head and Neck Cancer Open
View article: Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility
Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility Open
Centrosomes control cell motility, polarity and migration that is thought to be mediated by their microtubule-organizing capacity. Here we demonstrate that WNT signalling drives a distinct form of non-directional cell motility that require…
View article: Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility
Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility Open
Centrosomes control cell motility, polarity and migration that is thought to be mediated by their microtubule-organizing capacity. Here we demonstrate that WNT signalling drives a distinct form of non-directional cell motility that require…
View article: High-content imaging and analysis to quantify the nuclear to cytoplasmic ratio of TGFβ and hippo effectors in mammalian cells
High-content imaging and analysis to quantify the nuclear to cytoplasmic ratio of TGFβ and hippo effectors in mammalian cells Open
View article: Ancestral roles of atypical cadherins in planar cell polarity
Ancestral roles of atypical cadherins in planar cell polarity Open
Significance Planar cell polarization, PCP, describes a form of organization where every cell within a group acquires the same planar characteristics, whether it is orientation of cell division, direction of migration, or localization of a…
View article: Modeling the Control of TGF-β/Smad Nuclear Accumulation by the Hippo Pathway Effectors, Taz/Yap
Modeling the Control of TGF-β/Smad Nuclear Accumulation by the Hippo Pathway Effectors, Taz/Yap Open
View article: ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway
ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway Open
View article: Avoidance of apoptotic death via a hyperploid salvage survival pathway after platinum treatment in high grade serous carcinoma cell line models
Avoidance of apoptotic death via a hyperploid salvage survival pathway after platinum treatment in high grade serous carcinoma cell line models Open
The alkylating agent platinum is first-line chemotherapy treatment for high-grade serous carcinomas (HGSC) of tubal-ovarian origin. Platinum compounds cause DNA damage and induce apoptotic cell death in the bulk tumor population. However, …
View article: Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility
Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility Open
View article: Ancestral role of Fat-like cadherins in planar cell polarity
Ancestral role of Fat-like cadherins in planar cell polarity Open
Fat family cadherins are enormous proteins that regulate planar cell polarity (PCP) and cell adhesion in bilaterian animals. Their evolutionary origin can be traced back to prebilaterian species, but their ancestral function(s) are unknown…
View article: Identification of Acquired Notch3 Dependency in Metastatic Head and Neck Cancer
Identification of Acquired Notch3 Dependency in Metastatic Head and Neck Cancer Open
View article: Excess Polθ functions in response to replicative stress in homologous recombination-proficient cancer cells
Excess Polθ functions in response to replicative stress in homologous recombination-proficient cancer cells Open
DNA polymerase theta (Polθ) is a specialized A-family DNA polymerase that functions in processes such as translesion synthesis (TLS), DNA double-strand break repair and DNA replication timing. Overexpression of POLQ, the gene encoding Polθ…
View article: A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface Open
View article: PTEN regulates cilia through Dishevelled
PTEN regulates cilia through Dishevelled Open
View article: The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression
The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression Open