Mikhail Syromyatnikov
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View article: Study of the effect of lipophilic cryofractions of spleen and placenta of cattle on mice under conditions of genotoxic action of mitomycin
Study of the effect of lipophilic cryofractions of spleen and placenta of cattle on mice under conditions of genotoxic action of mitomycin Open
The aim of this work was to study the antimutagenic and DNA-protective effects of lipophilic cryofractions of bovine spleen and placenta in mice with mitomycin (MM)-induced genotoxicity. The effect of lipophilic cryofraction of bovine sple…
View article: Analysis of the relative content of probiotic bacteria in the intestines of farm animals using genetic methods
Analysis of the relative content of probiotic bacteria in the intestines of farm animals using genetic methods Open
Probiotics are microorganisms that have beneficial properties that can have beneficial effects on the host organism. Chickens, pigs, and cattle are the most common farm animals around the world. In this regard, maintaining the microbial ba…
View article: Changes in L-Carnitine Metabolism Affect the Gut Microbiome and Influence Sexual Behavior Through the Gut–Testis Axis
Changes in L-Carnitine Metabolism Affect the Gut Microbiome and Influence Sexual Behavior Through the Gut–Testis Axis Open
L-carnitine and Mildronate are substances that can significantly rearrange the energy metabolism of cells. This can potentially cause changes in the bacterial composition of the gut microbiome and affect testis functionality and male sexua…
View article: The effect of the drug "Prostimul" on the formation of intestinal microbiome and mitotic activity of cells of the small division intestines of piglets with prenatal hypotrophy
The effect of the drug "Prostimul" on the formation of intestinal microbiome and mitotic activity of cells of the small division intestines of piglets with prenatal hypotrophy Open
A significant problem of modern industrial pig farming is the birth of a significant number of piglets with low live weight. A major problem is the further preservation and viability of physiologically immature piglets. The article describ…
View article: THE EFFECT OF ENROFLOXAVETFERON AND GENTABIFERON-B ON BLOOD PARAMETERS OF COWS IN THE TREATMENT OF ENDOMETRITIS
THE EFFECT OF ENROFLOXAVETFERON AND GENTABIFERON-B ON BLOOD PARAMETERS OF COWS IN THE TREATMENT OF ENDOMETRITIS Open
Impaired fertility in cattle is the cause of economic losses in livestock farms. Complex treatment of cows with acute endometritis may include various approaches, including the use of antibiotics and interferon-based drugs. The therapeutic…
View article: The effect of Viferon-B and Enrofloxavetferon-B on the microbiota of utero-vaginal secretions of cows with endometritis
The effect of Viferon-B and Enrofloxavetferon-B on the microbiota of utero-vaginal secretions of cows with endometritis Open
Endometritis is one of the most frequently detected diseases of cattle, which is associated with disturbances in the microbial balance of the uterine cavity. This pathological process leads to disturbances in animal fertility, and, consequ…
View article: <b>Antibiotic resistance in mastitis-causing bacteria: Exploring antibiotic-resistance genes, underlying mechanisms, and their implications for dairy animal and public health</b>
<b>Antibiotic resistance in mastitis-causing bacteria: Exploring antibiotic-resistance genes, underlying mechanisms, and their implications for dairy animal and public health</b> Open
The development and spread of superbugs, which are bacterial strains resistant to several types of antibiotics, threatening the lives of myriad people and animals worldwide, is one of the most concerning issues facing both global and anima…
View article: Effect of interferon on broilers' fecal microbiome composition
Effect of interferon on broilers' fecal microbiome composition Open
Objective: The purpose of our study was to investigate the effect of chicken interferon on the intestinal microbiota of broiler chickens. Materials and Methods: The study used next-generation sequencing on the Ion Torrent pragmatic general…
View article: Study of antigenotoxic effect of hydrophilic cryofractions of some tissue of cattle
Study of antigenotoxic effect of hydrophilic cryofractions of some tissue of cattle Open
In conditions of environmental distress and high anthropogenic load in agricultural activities, the task of maintaining the integrity of the animal genome arises. One way to solve this problem is to use drugs that have an antimutagenic eff…
View article: Comparative analysis of the prevalence of antibiotic resistance genes in the intestine microbiome of piglets, cows and broiler chickens
Comparative analysis of the prevalence of antibiotic resistance genes in the intestine microbiome of piglets, cows and broiler chickens Open
Antibiotic resistance is a serious problem in the agricultural sector of the economy worldwide. The intestines of animals can be a reservoir for antibiotic resistance genes. The aim of the work was a comparative analysis of the prevalence …
View article: The female reproductive tract microbiome and obesity
The female reproductive tract microbiome and obesity Open
High-throughput 16S rRNA sequencing has allowed us to identify novel microorganisms and their relationships in the female reproductive tract. However, in obese patients, the female reproductive tract microbiome, unlike the intestinal micro…
View article: Fecal Microbiota Characteristics in Constipation-Predominant and Mixed-Type Irritable Bowel Syndrome
Fecal Microbiota Characteristics in Constipation-Predominant and Mixed-Type Irritable Bowel Syndrome Open
Background: Irritable bowel syndrome (IBS) is a common condition that affects the lifestyle of patients. It is associated with significant changes in the composition of the gut microbiome, but the underlying microbial mechanisms remain to …
View article: Effect of Probiotic Bacteria on the Gut Microbiome of Mice with Lipopolysaccharide-Induced Inflammation
Effect of Probiotic Bacteria on the Gut Microbiome of Mice with Lipopolysaccharide-Induced Inflammation Open
The role of lipopolysaccharide (LPS) in the development of diseases is clear, but the specific mechanisms remain poorly understood. This study aimed to investigate the microbiome aberrations in the guts of mice against the background of LP…
View article: Molecular Methods for Detecting Microorganisms in Beverages
Molecular Methods for Detecting Microorganisms in Beverages Open
Beverages are an integral component of a person’s food package. Various types of microorganisms widely contaminate beverages. This review presents current research data aimed at identifying dominant microorganisms in beverages and molecula…
View article: Pattern‐Recognition Receptors and Cervical Microbiome in Patients with Early Miscarriages
Pattern‐Recognition Receptors and Cervical Microbiome in Patients with Early Miscarriages Open
Early miscarriages are one of the main causes of reproductive losses. The objective of this study was to estimate Toll‐ and NOD‐like receptors mRNA expression levels and their correlation with microbiome composition in the endocervix of pa…
View article: EFFECT OF THE DRUG FERONAMIN ON THE EXPRESSION LEVEL OF PRO- AND ANTI-INFLAMMATORY CYTOKINE GENES ON THE BACKGROUND OF VACCINATION AGAINST PCV2
EFFECT OF THE DRUG FERONAMIN ON THE EXPRESSION LEVEL OF PRO- AND ANTI-INFLAMMATORY CYTOKINE GENES ON THE BACKGROUND OF VACCINATION AGAINST PCV2 Open
The study presents the data on the effect of using the drug Feronamin based on specific recombinant porcine interferons on the relative level of gene expression during vaccination against porcine circovirus infection (PCV2). The research w…
View article: Study of microbiome aberrations in patients with irritable bowel syndrome with diarrhea by next-generation sequencing
Study of microbiome aberrations in patients with irritable bowel syndrome with diarrhea by next-generation sequencing Open
To investigate the microbiological composition of the intestines of patients with IBS-D
View article: Association of milk microbiome with bovine mastitis before and after antibiotic therapy
Association of milk microbiome with bovine mastitis before and after antibiotic therapy Open
Background and Aim: Mastitis is recognized as the most common disease in cattle and causes economic losses in the dairy industry. A number of opportunistic bacterial taxa have been identified as causative agents for this disease. Conventio…
View article: Bacterial Composition of Dairy Base during Fermentation
Bacterial Composition of Dairy Base during Fermentation Open
Probiotic starters are a biological product based on lactic acid bacteria. Their metabolic characteristics determine the properties of the final products. This study evaluated the bacterial composition of a starter culture at various time …
View article: Features of intestinal microbiota diversity in elderly patients with metabolic disorders (literature review)
Features of intestinal microbiota diversity in elderly patients with metabolic disorders (literature review) Open
В статье дается оценка биоразнообразие кишечной микробиоты у пациентов пожилого возраста с метаболическими нарушениями
View article: Cervical and Vaginal Microbiomes in Early Miscarriages and Ongoing Pregnancy with and without Dydrogesterone Usage
Cervical and Vaginal Microbiomes in Early Miscarriages and Ongoing Pregnancy with and without Dydrogesterone Usage Open
Emerging evidence suggests that the reproductive tract microbiota is a key modulator of local inflammatory and immune pathways throughout pregnancy and may subsequently impact pregnancy outcomes. In this study, our objective was to analyze…
View article: The effect of fucoidan and inulin on the expression of Lactobacillus plantarum metabolism genes
The effect of fucoidan and inulin on the expression of Lactobacillus plantarum metabolism genes Open
The most stable reference gene in Lactobacillus plantarum was identified. It was found that the expression of the rpoD gene was most stable with the addition of fucoidan and inulin. The level of expression of the usp gene in L. plantarum b…
View article: THE ROLE OF THE INTESTINAL MICROBIOTA IN THE DEVELOPMENT OF INFLAMMATORY DISEASES OF THE INTESTINE
THE ROLE OF THE INTESTINAL MICROBIOTA IN THE DEVELOPMENT OF INFLAMMATORY DISEASES OF THE INTESTINE Open
Inflammatory bowel diseases (IBD) occupy a leading position in the structure of diseases of the gastrointestinal tract (GIT), as they are a progressive chronic pathology with an autoimmune type of inflammation. Changes in indicators of gen…
View article: Characteristics of the Fecal Microbiome of Piglets with Diarrhea Identified Using Shotgun Metagenomics Sequencing
Characteristics of the Fecal Microbiome of Piglets with Diarrhea Identified Using Shotgun Metagenomics Sequencing Open
Diarrhea in piglets is one of the most common diseases leading to high mortality and, as a result, to economic losses. Shotgun metagenomic sequencing was performed on the DNBSEQ-G50, MGI system to study the role of the fecal microbiome in …
View article: Role of the FABP gene family in the regulation of lipid metabolism of the common carp (Cyprinus carpio) breeding population
Role of the FABP gene family in the regulation of lipid metabolism of the common carp (Cyprinus carpio) breeding population Open
The study of the genetic aspects of the regulation of lipid metabolism at the present stage is of particular importance. To develop a complete differentiated approach to assessing the initiation and progression of metabolic disorders, it i…
View article: ASSESSMENT OF THE RELATIVE ABUNDANCE OF ANTIBIOTIC RESISTANCE GENES OF BACTERIA IN THE GUT OF PIGLETS (SUS SCROFA DOMESTICUS) IN THE EARLY NEONATAL PERIOD
ASSESSMENT OF THE RELATIVE ABUNDANCE OF ANTIBIOTIC RESISTANCE GENES OF BACTERIA IN THE GUT OF PIGLETS (SUS SCROFA DOMESTICUS) IN THE EARLY NEONATAL PERIOD Open
The article presents the assessment of the presence and relative amount of antibiotic resistance genes of bacteria in the gut microbiome of piglets in the early neonatal period. The genes for beta-lactam antibiotics (penicillins, cephalosp…
View article: EFFECT OF THE SPECIES-SPECIFIC DRUG PROSTIMUL ON THE LEVEL OF IL-1 GENE EXPRESSION IN NEWBORN PIGLETS WITH COLIBACTERIOSIS
EFFECT OF THE SPECIES-SPECIFIC DRUG PROSTIMUL ON THE LEVEL OF IL-1 GENE EXPRESSION IN NEWBORN PIGLETS WITH COLIBACTERIOSIS Open
The article presents the data on the expression level of the pro-inflammatory cytokine interleukin-1 (IL-1) in piglets 3-5 days of age diseased with colibacteriosis, against the background of the use of the species-specific drug Prostimul,…
View article: ABUNDANCE OF BACTERIAL ANTIBIOTIC RESISTANCE GENES IN SWINE DURING THE FATTENING PERIOD (SUS SCROFA DOMESTICUS)
ABUNDANCE OF BACTERIAL ANTIBIOTIC RESISTANCE GENES IN SWINE DURING THE FATTENING PERIOD (SUS SCROFA DOMESTICUS) Open
The aim of the study was to analyze the gut microbiome of swine during the fattening period, aimed at identify-ing antibiotic resistance genes. High-throughput sequencing allowed a total of 119 636 readings, bioinformatic re-search of whic…
View article: STUDY OF THE DIVERSITY OF FUNGAL MICROORGANISMS IN THE GUT OF SWINE WITH DIFFERENT FEED CONVERSION RATE
STUDY OF THE DIVERSITY OF FUNGAL MICROORGANISMS IN THE GUT OF SWINE WITH DIFFERENT FEED CONVERSION RATE Open
The paper presents the results of study on high-throughput sequencing of the fungal microbiome in the intesti-nal tract of swine, as well as an assessment of the influence of the feed conversion rate on the biodiversity of the fun-gal comm…