Milan Kratochvíl
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View article: Diagnostika a léčba život ohrožujícího krvácení u dětských pacientů v intenzivní a perioperační péči 2024
Diagnostika a léčba život ohrožujícího krvácení u dětských pacientů v intenzivní a perioperační péči 2024 Open
View article: Proposal for updating terminology in end‑of‑life care in intensive care units in the Czech Republic
Proposal for updating terminology in end‑of‑life care in intensive care units in the Czech Republic Open
View article: Effects of two different dexamethasone dosing regimens on ventilator-free days and long-term mortality in COVID-19 patients with moderate-to-severe ARDS: the REMED randomized clinical trial
Effects of two different dexamethasone dosing regimens on ventilator-free days and long-term mortality in COVID-19 patients with moderate-to-severe ARDS: the REMED randomized clinical trial Open
View article: Coffee polyphenols ameliorate early-life stress-induced cognitive deficits in male mice
Coffee polyphenols ameliorate early-life stress-induced cognitive deficits in male mice Open
View article: A tagging polymorphism in fat mass and obesity-associated (<i>FTO</i>) gene is associated with sepsis status in children
A tagging polymorphism in fat mass and obesity-associated (<i>FTO</i>) gene is associated with sepsis status in children Open
Introduction Sepsis is one of the most common causes of death in patients admitted to intensive care units (ICUs). The development of sepsis is significantly influenced by genetic predisposition. In this study, we highlight a potential ass…
View article: Dexamethasone doses in patients with <scp>COVID</scp>‐19 and hypoxia: <scp>A</scp> systematic review and meta‐analysis
Dexamethasone doses in patients with <span>COVID</span>‐19 and hypoxia: <span>A</span> systematic review and meta‐analysis Open
Background The optimal dose of dexamethasone for severe/critical COVID‐19 is uncertain. We compared higher versus standard doses of dexamethasone in adults with COVID‐19 and hypoxia. Methods We searched PubMed and trial registers until 23 …
View article: COVID-19-Associated Paediatric Inflammatory Multisystem Syndrome (PIMS-TS) in Intensive Care: A Retrospective Cohort Trial (PIMS-TS INT)
COVID-19-Associated Paediatric Inflammatory Multisystem Syndrome (PIMS-TS) in Intensive Care: A Retrospective Cohort Trial (PIMS-TS INT) Open
Paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-TS) is a new disease in children and adolescents that occurs after often asymptomatic or mild COVID-19. It can be manifested by different clinical sympt…
View article: Early-life stress and early diet modulate the risk for Alzheimer’s disease: focus on microglia and polyunsaturated fatty acids in APP/PS1 mice
Early-life stress and early diet modulate the risk for Alzheimer’s disease: focus on microglia and polyunsaturated fatty acids in APP/PS1 mice Open
View article: Airway Management in Pediatric Patients: Cuff-Solved Problem?
Airway Management in Pediatric Patients: Cuff-Solved Problem? Open
Traditionally, uncuffed tubes were used in pediatric patients under 8 years in pursuit of reducing the risk of postextubation stridor. Although computed tomography and magnetic resonance imaging studies confirmed that the subglottic area r…
View article: Nutrition in Pediatric Intensive Care: A Narrative Review
Nutrition in Pediatric Intensive Care: A Narrative Review Open
Nutrition support in pediatric intensive care is an integral part of a complex approach to treating critically ill children. Smaller energy reserves with higher metabolic demands (a higher basal metabolism rate) compared to adults makes ch…
View article: Critically Ill Pediatric Patient and SARS-CoV-2 Infection
Critically Ill Pediatric Patient and SARS-CoV-2 Infection Open
In December 2019 SARS-CoV-2 initiated a worldwide COVID-19 pandemic, which is still ongoing in 2022. Although adult elderly patients with chronic preexisting diseases had been identified as the most vulnerable group, COVID-19 has also had …
View article: Clinical practise of administration of systemic corticosteroids among critically ill patients with COVID-19 in the Czech Republic: survey (ASAP‑C)
Clinical practise of administration of systemic corticosteroids among critically ill patients with COVID-19 in the Czech Republic: survey (ASAP‑C) Open
CĂl studie: LĂŠÄba pacientĹŻ s tÄĹžkĂ˝m prĹŻbÄhem onemocnÄnĂ covid-19 (Coronavirus Disease 2019) kortikoidy je doporuÄena SvÄtovou zdravotnickou organizacĂ na zĂĄkladÄ vĂ˝sledkĹŻ studie RECOVERY. StĂĄle vĹĄak existuje mnoho otĂĄz…
View article: Effect of dexamethasone in patients with ARDS and COVID-19 (REMED trial)—study protocol for a prospective, multi-centre, open-label, parallel-group, randomized controlled trial
Effect of dexamethasone in patients with ARDS and COVID-19 (REMED trial)—study protocol for a prospective, multi-centre, open-label, parallel-group, randomized controlled trial Open
View article: Unvaccinated child tetanus from nasal toy battery
Unvaccinated child tetanus from nasal toy battery Open
We present the case report of an unvaccinated Czech child with tetanus. The child had not received any vaccines due to its parent's refusal. The disease originated from the wound in the nose caused by a small flat battery. The typical onse…
View article: Videolaryngoscopy vs. Direct Laryngoscopy for Elective Airway Management in Paediatric Anaesthesia
Videolaryngoscopy vs. Direct Laryngoscopy for Elective Airway Management in Paediatric Anaesthesia Open
BACKGROUND The indirect visualisation of the glottic area with a videolaryngoscope could improve intubation conditions which may possibly lead to a higher success rate of the first intubation attempt. OBJECTIVE Comparison of videolaryngosc…
View article: Effect of Dexamethasone In Patients With ARDS And COVID-19 (REMED Trial) – Study Protocol For A Prospective, Multi-Centre, Open-Label, Parallel-Group, Randomized Controlled Trial
Effect of Dexamethasone In Patients With ARDS And COVID-19 (REMED Trial) – Study Protocol For A Prospective, Multi-Centre, Open-Label, Parallel-Group, Randomized Controlled Trial Open
Background : Since December 2019, SARS-Co-2 virus has infected millions of people worldwide. In patients with COVID-19 pneumonia in need for oxygen therapy or mechanical ventilation, dexamethasone 6 mg per day is currently recommended. How…
View article: Pediatric Patient with Ischemic Stroke: Initial Approach and Early Management
Pediatric Patient with Ischemic Stroke: Initial Approach and Early Management Open
Acute Ischemic Stroke (AIS) in children is an acute neurologic emergency associated with significant morbidity and mortality. Although the incidence of AIS in pediatric patients is considerably lower than in adults, the overall cumulative …
View article: Effect of dexamethasone in patients with ARDS and COVID-19 – prospective, multi-centre, open-label, parallel-group, randomised controlled trial (REMED trial): A structured summary of a study protocol for a randomised controlled trial
Effect of dexamethasone in patients with ARDS and COVID-19 – prospective, multi-centre, open-label, parallel-group, randomised controlled trial (REMED trial): A structured summary of a study protocol for a randomised controlled trial Open
View article: Effect of dexamethasone in patients with ARDS and COVID-19 – prospective, multi-centre, open-label, parallel-group, randomised controlled trial (REMED trial): A structured summary of a study protocol for a randomised controlled trial
Effect of dexamethasone in patients with ARDS and COVID-19 – prospective, multi-centre, open-label, parallel-group, randomised controlled trial (REMED trial): A structured summary of a study protocol for a randomised controlled trial Open
ObjectivesThe primary objective of this study is to test the hypothesis that administration of dexamethasone 20 mg is superior to a 6 mg dose in adult patients with moderate or severe ARDS due to confirmed COVID-19. The secondary objective…
View article: Difficult airway prediction in paediatric anaesthesia (Diffair): Prospective observational study
Difficult airway prediction in paediatric anaesthesia (Diffair): Prospective observational study Open
We found minimal efficacy for preanaesthesia difficult airway prediction.
View article: Rapid sequence induction
Rapid sequence induction Open
BACKGROUND Rapid sequence induction (RSI) is a standard procedure, which should be implemented in all patients with a risk of aspiration/regurgitation during anaesthesia induction. OBJECTIVE The primary aim was to evaluate clinical practic…
View article: Depth of neuromuscular blockade and the perioperative conditions in laparoscopic surgery in pediatric population: Randomized controlled pilot trial
Depth of neuromuscular blockade and the perioperative conditions in laparoscopic surgery in pediatric population: Randomized controlled pilot trial Open
• Deep neuromuscular blockade is not linked with better surgical conditions. • Intubation and extubation times with rocuronium are superior to cisatracurium. • Deep blockade was not associated with increased rate of complications.
View article: Předpoklady k učitelské profesi
Předpoklady k učitelské profesi Open
Výzkum byl zaměřen na studenty L ročníku Fakulty pedagogické a studenty I. ročníku Fakulty strojní a textilní, kteří se v rámci doplňujícího pedagogického studia připravují na učitelskou profesi. Cílem výzkumu bylo odhalit motivační faktor…
View article: T. G. Masaryk a naše některé současné pedagogické problémy (historický exkurz)
T. G. Masaryk a naše některé současné pedagogické problémy (historický exkurz) Open
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