Milena Stránská
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View article: Pulsed Electric Fields Reshape the Malting Barley Metabolome: Insights from UHPLC-HRMS/MS
Pulsed Electric Fields Reshape the Malting Barley Metabolome: Insights from UHPLC-HRMS/MS Open
The Pulsed Electric Field (PEF) technique represents a modern technology for treating and processing food and agricultural raw materials. The application of high-voltage electric pulses has been shown to modify macrostructure, improve extr…
View article: Pharmacokinetics of Cannabidiol in Rat Brain Tissue After Single-Dose Administration of Different Formulations
Pharmacokinetics of Cannabidiol in Rat Brain Tissue After Single-Dose Administration of Different Formulations Open
Cannabidiol (CBD), a phytocannabinoid commonly isolated from chemotype III Cannabis sativa plants, is known for its therapeutic potential. However, comprehensive information on its bioavailability is still lacking. The key objective of thi…
View article: Pulsed Electric Field Treatment Modulates Gene Expression and Stress Responses in Fusarium-Infected Malting Barley
Pulsed Electric Field Treatment Modulates Gene Expression and Stress Responses in Fusarium-Infected Malting Barley Open
Malting is a critical step in barley (Hordeum vulgare) processing, transforming grain into a key raw material for brewing and food production. However, the process is often compromised by Fusarium spp., pathogens responsible for Fusarium H…
View article: What Happens Inside the Germinating Grain After Microbial Decontamination by Pulsed Electric Field? Data-Driven Multi-Omics Helps Find the Answer
What Happens Inside the Germinating Grain After Microbial Decontamination by Pulsed Electric Field? Data-Driven Multi-Omics Helps Find the Answer Open
Pulsed electric field (PEF) has previously been recognized as a method of gentle food processing, and its use has been shown to be helpful in reducing the levels of toxigenic Fusarium micromycetes developed during malting. The aim of this …
View article: Pulsed Electric Field Induces Significant Changes in the Metabolome of Fusarium Species and Decreases Their Viability and Toxigenicity
Pulsed Electric Field Induces Significant Changes in the Metabolome of Fusarium Species and Decreases Their Viability and Toxigenicity Open
Fusarium fungi are widespread pathogens of food crops, primarily associated with the formation of mycotoxins. Therefore, effective mitigation strategies for these toxicogenic microorganisms are required. In this study, the potential of pul…
View article: Glycosylated mycotoxins: a hidden enemy
Glycosylated mycotoxins: a hidden enemy Open
Comprehensive review of glycosylated mycotoxins in the food chain: their formation, analytical challenges, health effects and toxicology, synthetic methods, deglycosylation strategies, and regulatory aspects.
View article: Application of Pulsed Electric Field During Malting: Impact on Fusarium Species Growth and Mycotoxin Production
Application of Pulsed Electric Field During Malting: Impact on Fusarium Species Growth and Mycotoxin Production Open
The increasing contamination of cereals by micromycetes and mycotoxins during malting still poses an unresolved food safety problem. This study characterises the potential of the novel, rapidly developing food production technology of Puls…
View article: What Happens Inside the Germinating Grain After Microbial Decontamination by Pulsed Electric Field? Data‐Driven Multi‐Omics Helps Find the Answer
What Happens Inside the Germinating Grain After Microbial Decontamination by Pulsed Electric Field? Data‐Driven Multi‐Omics Helps Find the Answer Open
Pulsed electric field (PEF) has previously been recognized as a method of gentle food processing and its use has been shown to be helpful in reducing the levels of toxigenic Fusarium micromycetes developed during malting. The aim of this s…
View article: Effect of pulsed electric field on viability of Fusarium micromycetes
Effect of pulsed electric field on viability of Fusarium micromycetes Open
Fusarium species are one of the most studied fungal pathogens of cereals. They cause Fusarium head blight or stem base diseases that are risky not only in terms of yield losses but also due to mycotoxins production. Several strategies are …
View article: Pulsed electric field treatment applied to barley before malting reduces Fusarium pathogens without compromising the quality of the final malt
Pulsed electric field treatment applied to barley before malting reduces Fusarium pathogens without compromising the quality of the final malt Open
The growth of micromycetes and the associated production of mycotoxins during malting represents a potential safety issue and an economic challenge regarding the quality of beer as a product manufactured from malt. The treatment of malted …
View article: Pulsed Electric Field Induces Significant Changes in the Metabolome of Fusarium Species and Decreases Their Viability and Toxigenicity
Pulsed Electric Field Induces Significant Changes in the Metabolome of Fusarium Species and Decreases Their Viability and Toxigenicity Open
View article: Pulsed Electric Field Treatment Applied to Barley Before Malting – Does Reduction of Fusarium Pathogens Compromise the Quality of the Final Malt?
Pulsed Electric Field Treatment Applied to Barley Before Malting – Does Reduction of Fusarium Pathogens Compromise the Quality of the Final Malt? Open
View article: Pulsed Electric Field Reduces Fusarium Micromycetes and Mycotoxins During Malting
Pulsed Electric Field Reduces Fusarium Micromycetes and Mycotoxins During Malting Open
View article: Safety Assessment of Six Mycotoxins Using Four in Vitro Assays for Genotoxicity Characterisation
Safety Assessment of Six Mycotoxins Using Four in Vitro Assays for Genotoxicity Characterisation Open
View article: The Ameliorating Effects of n-3 Polyunsaturated Fatty Acids on Liver Steatosis Induced by a High-Fat Methionine Choline-Deficient Diet in Mice
The Ameliorating Effects of n-3 Polyunsaturated Fatty Acids on Liver Steatosis Induced by a High-Fat Methionine Choline-Deficient Diet in Mice Open
The pathogenesis of non-alcoholic fatty liver disease (NAFLD) is associated with abnormalities of liver lipid metabolism. On the contrary, a diet enriched with n-3 polyunsaturated fatty acids (n-3-PUFAs) has been reported to ameliorate the…
View article: Developments in mycotoxin analysis: an update for 2021-22
Developments in mycotoxin analysis: an update for 2021-22 Open
This review summarises developments published in the period from mid-2021 to mid-2022 on the analysis of a variety of matrices for mycotoxins. Important developments in all aspects of mycotoxin analysis, from sampling and quality assurance…
View article: Poster No. 031 Anti-inflammatory potential of cannabinoid extracts
Poster No. 031 Anti-inflammatory potential of cannabinoid extracts Open
Inflammation plays a substantial role in the process of atherosclerosis. The key players are monocytes transformed to macrophages. Limited experience with anti-inflammatory drugs is described – antibodies for IL-1 (CANTOS) and colchicine (…
View article: Developments in mycotoxin analysis: an update for 2020-2021
Developments in mycotoxin analysis: an update for 2020-2021 Open
This review summarises developments published in the period from mid-2020 to mid-2021 on the analysis of a number of diverse matrices for mycotoxins. Notable developments in all aspects of mycotoxin analysis, from sampling and quality assu…
View article: Fungal Endophytes of Vitis vinifera—Plant Growth Promoters or Potentially Toxinogenic Agents?
Fungal Endophytes of Vitis vinifera—Plant Growth Promoters or Potentially Toxinogenic Agents? Open
Fungal endophytes occurring in grapevine (Vitis vinifera L.) are usually important sources of various compounds with biological activities with great potential for use in agriculture. Nevertheless, many species isolated from this plant bel…
View article: Fungal Endophytes of Vitis vinifera—Plant Growth Promotion Factors
Fungal Endophytes of Vitis vinifera—Plant Growth Promotion Factors Open
Endophytes are microorganisms that live asymptomatically inside plant tissues. They are beneficial to their host in many aspects, especially as a defense against foreign phytopathogens through the production of a variety of metabolites. Th…
View article: The Effect of Mycotoxins and Silymarin on Liver Lipidome of Mice with Non-Alcoholic Fatty Liver Disease
The Effect of Mycotoxins and Silymarin on Liver Lipidome of Mice with Non-Alcoholic Fatty Liver Disease Open
Milk thistle-based dietary supplements have become increasingly popular. The extract from milk thistle (Silybum marianum) is often used for the treatment of liver diseases because of the presence of its active component, silymarin. However…
View article: Developments in mycotoxin analysis: an update for 2019-2020
Developments in mycotoxin analysis: an update for 2019-2020 Open
This review summarises developments on the analysis of various matrices for mycotoxins published in the period from mid-2019 to mid-2020. Notable developments in all aspects of mycotoxin analysis, from sampling and quality assurance/qualit…
View article: Potential of microalgae as source of health-beneficial bioactive components in produced eggs
Potential of microalgae as source of health-beneficial bioactive components in produced eggs Open
View article: In Silico and In Vitro Studies of Mycotoxins and Their Cocktails; Their Toxicity and Its Mitigation by Silibinin Pre-Treatment
In Silico and In Vitro Studies of Mycotoxins and Their Cocktails; Their Toxicity and Its Mitigation by Silibinin Pre-Treatment Open
Mycotoxins found in randomly selected commercial milk thistle dietary supplement were evaluated for their toxicity in silico and in vitro. Using in silico methods, the basic physicochemical, pharmacological, and toxicological properties of…
View article: Complex Evaluation of Antioxidant Capacity of Milk Thistle Dietary Supplements
Complex Evaluation of Antioxidant Capacity of Milk Thistle Dietary Supplements Open
Numerous in vitro assays are used to characterize the antioxidant properties of natural-based matrices. However, many of them generate contradictory and non-compliant results. In our study, we focused on the characterization of traditional…
View article: Poor chemical and microbiological quality of the commercial milk thistle-based dietary supplements may account for their reported unsatisfactory and non-reproducible clinical outcomes
Poor chemical and microbiological quality of the commercial milk thistle-based dietary supplements may account for their reported unsatisfactory and non-reproducible clinical outcomes Open
View article: Authentication of meat species and net muscle proteins: updating of an old concept
Authentication of meat species and net muscle proteins: updating of an old concept Open
The aim of the study was to develop an efficient method for assessment of meat origin and determination of net muscle protein (NMP; based on amino acids and β-alanylhistidine dipeptides) in meat products using the ultra-high performance li…
View article: Analysis of phosphodiesterase type 5 inhibitors as possible adulterants of botanical-based dietary supplements: extensive survey of preparations available at the Czech market
Analysis of phosphodiesterase type 5 inhibitors as possible adulterants of botanical-based dietary supplements: extensive survey of preparations available at the Czech market Open
Popularity of natural-based preparations supporting the sexual potency significantly increased in recent years, which also led to the increase of illegal use of phosphodiesterase type 5 inhibitor (PDE-5) in sexual performance enhancement p…
View article: Advanced LC–MS-based methods to study the co-occurrence and metabolization of multiple mycotoxins in cereals and cereal-based food
Advanced LC–MS-based methods to study the co-occurrence and metabolization of multiple mycotoxins in cereals and cereal-based food Open
View article: Antidiabetic Compounds in Stem Juice from Banana
Antidiabetic Compounds in Stem Juice from Banana Open
The stem juices from Musa × paradisiaca L. banana plants cultivated in their original natural habitat in Vietnam and those cultivated in a greenhouse in the Czech Republic were investigated for the presence of phytochemicals with antidiabe…