Miles G. Johnston
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View article: A MATHEMATICAL ANALYSIS OF PHYSIOLOGICAL AND MOLECULAR MECHANISMS THAT MODULATE PRESSURE GRADIENTS AND FACILITATE VENTRICULAR EXPANSION IN HYDROCEPHALUS.
A MATHEMATICAL ANALYSIS OF PHYSIOLOGICAL AND MOLECULAR MECHANISMS THAT MODULATE PRESSURE GRADIENTS AND FACILITATE VENTRICULAR EXPANSION IN HYDROCEPHALUS. Open
Perhaps the greatest paradox in the hydrocephalus field is the failure of researchers to consistently measure transmantle pressure gradients (ventricle to subarachnoid space) in either human or animal models of the communicating form of th…
View article: Experimental assessment of pro-lymphangiogenic growth factors in the treatment of post-surgical lymphedema following lymphadenectomy
Experimental assessment of pro-lymphangiogenic growth factors in the treatment of post-surgical lymphedema following lymphadenectomy Open
Introduction Lymphedema is a frequent consequence of lymph node excision during breast cancer surgery. Current treatment options are limited mainly to external compression therapies to limit edema development. We investigated previously, p…
View article: Lymphatic cerebrospinal fluid absorption is impaired in a kaolin-induced hydrocephalus model in the rat
Lymphatic cerebrospinal fluid absorption is impaired in a kaolin-induced hydrocephalus model in the rat Open
Materials and methods Kaolin (n = 10) or saline as control (n = 9) was introduced into the basal cisterns of Sprague Dawley rats and the development of hydrocephalus was assessed using MRI. The degree of ventriculomegaly was calculated for…
View article: Possible role of the cavernous sinus veins in cerebrospinal fluid absorption
Possible role of the cavernous sinus veins in cerebrospinal fluid absorption Open
The purpose of this investigation was to enhance our understanding of cerebrospinal fluid (CSF) absorption pathways. To achieve this, Microfil (a coloured silastic material) was infused into the subarachnoid space (cisterna magna) of sheep…
View article: Cerebrospinal fluid transport across the cribriform plate into extracranial lymphatics in rats: development and quantification
Cerebrospinal fluid transport across the cribriform plate into extracranial lymphatics in rats: development and quantification Open
Bifida Meeting abstracts - A single PDF containing all abstracts in this supplement is available here .
View article: Evidence of connections between cerebrospinal fluid and nasal lymphatic vessels in humans, non-human primates and other mammalian species
Evidence of connections between cerebrospinal fluid and nasal lymphatic vessels in humans, non-human primates and other mammalian species Open
Background The parenchyma of the brain does not contain lymphatics. Consequently, it has been assumed that arachnoid projections into the cranial venous system are responsible for cerebrospinal fluid (CSF) absorption. However, recent quant…
View article: The Relationship of Blood Lymphocytes to the Recirculating Lymphocyte Pool
The Relationship of Blood Lymphocytes to the Recirculating Lymphocyte Pool Open
Lymphocyte recirculation facilitates the detection and elimination of pathogens and the dissemination of immunologic memory. It is generally assumed that all small lymphocytes in the blood are actively recirculating, yet there is little qu…
View article: The Relationship of Blood Lymphocytes to the Recirculating Lymphocyte Pool
The Relationship of Blood Lymphocytes to the Recirculating Lymphocyte Pool Open
Lymphocyte recirculation facilitates the detection and elimination of pathogens and the dissemination of immunologic memory. It is generally assumed that all small lymphocytes in the blood are actively recirculating, yet there is little qu…
View article: The distribution of prostaglandins in afferent and efferent lymph from inflammatory sites.
The distribution of prostaglandins in afferent and efferent lymph from inflammatory sites. Open
Arachidonic acid labeled with (14)C was injected directly into lymph nodes that had been stimulated at various times with Escherichia coli. The efferent lymph was collected, and labeled catabolites were extracted and analyzed chromatograph…