Min Li
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View article: The Impact of Active Coping with Negative Public Opinion on Learning Power of Pre-service Primary School Teachers: The Mediating Role of Perceived Social Support
The Impact of Active Coping with Negative Public Opinion on Learning Power of Pre-service Primary School Teachers: The Mediating Role of Perceived Social Support Open
Background Recent years have witnessed increasing negative public discourse targeting primary school teachers, which has adversely affected pre-service teachers’ career commitment and impeded the development of their learning competence. M…
View article: The prognostic value of stress hyperglycemia ratio (SHR) in cardiac metabolic syndrome: dual-cohort evidence and machine learning modeling
The prognostic value of stress hyperglycemia ratio (SHR) in cardiac metabolic syndrome: dual-cohort evidence and machine learning modeling Open
Objective: This study aimed to evaluate the prognostic value of the stress hyperglycemia ratio (SHR) in predicting all-cause and cardiovascular disease (CVD) mortality among patients with cardiometabolic syndrome (CMS), leveraging large-…
View article: Brain structure characteristics in children with attention-deficit/hyperactivity disorder elucidated using traveling-subject harmonization
Brain structure characteristics in children with attention-deficit/hyperactivity disorder elucidated using traveling-subject harmonization Open
View article: Astragalin promotes HSCs ferroptosis through NCOA4 mediated ferritinophagy to alleviate liver fibrosis in zebrafish and mice
Astragalin promotes HSCs ferroptosis through NCOA4 mediated ferritinophagy to alleviate liver fibrosis in zebrafish and mice Open
Liver fibrosis is pathological progression of chronic liver disease. Recent research has focused on the activation of hepatic stellate cells (HSCs), highlighting their potential as targets for mitigating fibrosis. While herbal medicines an…
View article: Gut microbiota and tuberculosis infection: interaction and therapeutic potential
Gut microbiota and tuberculosis infection: interaction and therapeutic potential Open
Pulmonary tuberculosis (PTB), caused by Mycobacterium tuberculosis (MTB), is a serious chronic infectious disease. Although significant progress has been made in the prevention and treatment of MTB, current anti-tuberculosis therapi…
View article: Comparison of the effects of esketamine/midazolam and remifentanil/midazolam on respiratory mechanics in mechanically ventilated patients with acute respiratory distress syndrome
Comparison of the effects of esketamine/midazolam and remifentanil/midazolam on respiratory mechanics in mechanically ventilated patients with acute respiratory distress syndrome Open
Background Esketamine exerts analgesic effects and has pharmacological properties of bronchodilation and elevation of mean arterial pressure, making it an interesting analgesic agent for patients with ARDS. Therefore, we conducted a random…
View article: Detecting a potential causal relationship between plasma metabolites and myocardial infarction using bidirectional and two-step Mendelian randomization
Detecting a potential causal relationship between plasma metabolites and myocardial infarction using bidirectional and two-step Mendelian randomization Open
Some studies have shown that plasma metabolites may be associated with myocardial infarction (MI); however, the causal relationship between plasma metabolites and MI, as well as the potential mediating role of immune cells, remains unclear…
View article: Phytochemical Analysis of Semen Hoveniae and Its Potential Mechanism Against Alcoholic Liver Disease via an Integrated Approach Combining UHPLC‐Q‐TOF MS, Network Pharmacology, and Molecular Docking
Phytochemical Analysis of Semen Hoveniae and Its Potential Mechanism Against Alcoholic Liver Disease via an Integrated Approach Combining UHPLC‐Q‐TOF MS, Network Pharmacology, and Molecular Docking Open
Rationale Semen Hoveniae (SH), known as Zhijuzi in Chinese, is extensively utilized in China for the management of alcoholic liver disease (ALD) due to its recognized detoxification properties. Despite its extensive historical use, the det…
View article: The impact resistance tests of composite materials at room temperature and high temperature based on blade-like specimens
The impact resistance tests of composite materials at room temperature and high temperature based on blade-like specimens Open
Resin-based composites possess advantages such as light weight, high strength, and ease of molding. Their application in aeroengine casings can significantly enhance engine weight reduction, thrust-to-weight ratio, and fuel economy. This s…
View article: Single‐Droplet Dual‐Target Quantification of circRNA Biomarkers for Colorectal Cancer Screening
Single‐Droplet Dual‐Target Quantification of circRNA Biomarkers for Colorectal Cancer Screening Open
Circular RNAs (circRNAs) play a crucial role in the oncogenesis, progression, and chemoresistance of tumors. Here, two plasma circRNA biomarkers, circCK1γ3 and circWDR37 is identified and validated. Simultaneous analysis of these biomarker…
View article: Author response: Cellular characterization of the mouse collecting lymphatic vessels reveals that lymphatic muscle cells are the innate pacemaker cells
Author response: Cellular characterization of the mouse collecting lymphatic vessels reveals that lymphatic muscle cells are the innate pacemaker cells Open
View article: Efficient caproate production from ethanol and acetate via chain elongation reinforced by Fe/Fe3O4 in mixed culture system
Efficient caproate production from ethanol and acetate via chain elongation reinforced by Fe/Fe3O4 in mixed culture system Open
View article: Global m6A RNA and whole 5mC DNA methylation specifically contribute to cell replicative and premature senescence induced by extrinsic oxidative stress
Global m6A RNA and whole 5mC DNA methylation specifically contribute to cell replicative and premature senescence induced by extrinsic oxidative stress Open
Hydrogen peroxide (H 2 O 2 ) is a typical representative substance of environmental oxidative stress. Exogenous substances can alter epigenetic modifications from the DNA to the RNA level through oxidative stress. We investigated methylati…
View article: Enhancing Strain-level Phage-Host Prediction through Experimentally Vali-dated Negatives and Feature Optimization Strategies
Enhancing Strain-level Phage-Host Prediction through Experimentally Vali-dated Negatives and Feature Optimization Strategies Open
Accurate prediction of phage-host interactions at the strain level is critical for understanding microbial ecology and for developing phage-based therapeutics. However, existing models are limited by the lack of experimentally validated ne…
View article: OP0187 THE CLINICAL CHARACTERISTICS AND LONG-TERM OUTCOME OF SEROLOGICALLY ACTIVE CLINICALLY QUIESCENT IGG4-RELATED DISEASE: A RETROSPECTIVE STUDY
OP0187 THE CLINICAL CHARACTERISTICS AND LONG-TERM OUTCOME OF SEROLOGICALLY ACTIVE CLINICALLY QUIESCENT IGG4-RELATED DISEASE: A RETROSPECTIVE STUDY Open
View article: Notoginsenoside R2 attenuates hepatic fibrosis via STAT3-dependent hepatic stellate cells senescence induction and inflammatory microenvironment suppression
Notoginsenoside R2 attenuates hepatic fibrosis via STAT3-dependent hepatic stellate cells senescence induction and inflammatory microenvironment suppression Open
This study identified R2 as a regulator of STAT3 with dual antifibrotic effects: reduction of the inflammatory microenvironment and induction of senescence. These findings position R2 as a viable treatment candidate for HF, necessitating a…
View article: The association of sarcopenia, possible sarcopenia and cognitive impairment: A systematic review and meta-analysis
The association of sarcopenia, possible sarcopenia and cognitive impairment: A systematic review and meta-analysis Open
Objectives The study aimed to investigate the relationship between sarcopenia, possible sarcopenia, and cognitive impairment, and to analyze the impact of potential moderating factors. Methods A comprehensive search was conducted on PubMed…
View article: Programmed intermittent bolus for erector spinae plane block versus intercostal nerve block in minimally invasive direct coronary artery bypass surgery: a randomized controlled trial
Programmed intermittent bolus for erector spinae plane block versus intercostal nerve block in minimally invasive direct coronary artery bypass surgery: a randomized controlled trial Open
View article: Deciphering the Molecular Crosstalk of Endoplasmic Reticulum Stress and Immune Infiltration in Endometriosis
Deciphering the Molecular Crosstalk of Endoplasmic Reticulum Stress and Immune Infiltration in Endometriosis Open
Background Endometriosis (EMs), characterized by ectopic endometrial growth causing infertility. Endoplasmic reticulum stress (ERS) is an important cellular defense mechanism. However, the correlation between ERS and EMs remains unclear. W…
View article: Quantitative and Multiplexing Analysis of MicroRNAs by Direct Full-Length Sequencing in Nanopores
Quantitative and Multiplexing Analysis of MicroRNAs by Direct Full-Length Sequencing in Nanopores Open
MicroRNAs (miRNAs) play important regulatory roles in biology. Direct sequencing of miRNAs in full-length can reveal comprehensive information on their sequences, abundance, and modifications, which, however, has yet to be achieved due to …
View article: Risk of fall in middle-aged and older adult patients with chronic lung disease: evidence from the China Health and Retirement Longitudinal Study
Risk of fall in middle-aged and older adult patients with chronic lung disease: evidence from the China Health and Retirement Longitudinal Study Open
Background Chronic lung disease (CLD) not only manifests with respiratory symptoms but is often associated with various systemic conditions that may elevate the risk of falls. This study aimed to evaluate the independent association betwee…
View article: The resection of extraosseous osteosarcoma was accompanied by the occurrence of pulmonary metastasis and distal metastasis at the primary site: a case report
The resection of extraosseous osteosarcoma was accompanied by the occurrence of pulmonary metastasis and distal metastasis at the primary site: a case report Open
Background Extraskeletal osteosarcoma (ESOS) is a rare and aggressive malignancy, comprising approximately 1% of all soft tissue sarcomas and 4.3% of all osteosarcomas. It predominantly affects individuals between the ages of 48 and 60, wi…
View article: Endovascular treatment for cerebral venous thrombosis: a multicenter study in China
Endovascular treatment for cerebral venous thrombosis: a multicenter study in China Open
View article: Chronic myelogenous leukemia secondary to colon cancer: A case report
Chronic myelogenous leukemia secondary to colon cancer: A case report Open
BACKGROUND Colon cancer is a common malignancy of the digestive tract. An estimated 1148515 new cases of colon cancer were reported in 2020 worldwide. Chronic myeloid leukemia (CML) is a malignant tumor formed by the clonal proliferation o…
View article: Poria cocos-Derived Exosome-like Nanovesicles Alleviate Metabolic Dysfunction-Associated Fatty Liver Disease by Promoting Mitophagy and Inhibiting NLRP3 Inflammasome Activation
Poria cocos-Derived Exosome-like Nanovesicles Alleviate Metabolic Dysfunction-Associated Fatty Liver Disease by Promoting Mitophagy and Inhibiting NLRP3 Inflammasome Activation Open
Metabolic dysfunction-associated fatty liver disease (MAFLD) affects approximately one-quarter of the world’s adult population, and no effective therapeutic drugs are available. Poria cocos is a fungus used as a herb and food nutrient for …
View article: Enzymatic recycling of polyhydroxyalkanoate (PHA) bioplastics using PHA depolymerases
Enzymatic recycling of polyhydroxyalkanoate (PHA) bioplastics using PHA depolymerases Open
View article: The effect of exploratory trademark strategy on corporate cash holdings
The effect of exploratory trademark strategy on corporate cash holdings Open
View article: Metagenomic insights into correlation of microbiota and antibiotic resistance genes in the worker-pig-soil interface: A One Health surveillance on Chongming Island, China
Metagenomic insights into correlation of microbiota and antibiotic resistance genes in the worker-pig-soil interface: A One Health surveillance on Chongming Island, China Open
View article: Novel cancer stem cell-targeted retinoid ZSH-512 impedes colorectal cancer progress via KDM3A-mediated epigenetic reprogramming
Novel cancer stem cell-targeted retinoid ZSH-512 impedes colorectal cancer progress via KDM3A-mediated epigenetic reprogramming Open
Advanced colorectal cancer (CRC) exhibits weak responses to multiple therapies, primarily due to the presence of cancer stem cells (CSCs), which drive high recurrence rates, metastasis, and drug resistance. We have previously systematicall…
View article: ZBP1-mediated PANoptosis is a crucial lethal form in diverse keratinocyte death modalities in UVB-induced skin injury
ZBP1-mediated PANoptosis is a crucial lethal form in diverse keratinocyte death modalities in UVB-induced skin injury Open