Minchao Lai
YOU?
Author Swipe
View article: Unraveling α-synuclein and amylin co-aggregation: pathological insights and biomarker development for Parkinson's disease
Unraveling α-synuclein and amylin co-aggregation: pathological insights and biomarker development for Parkinson's disease Open
Background: Patients with diabetes have a higher morbidity in Parkinson's disease (PD) than others, but the mechanism underlying this link remains controversial. The co-aggregation of α-synuclein (α-syn) and amylin has been hypothes…
View article: Ablation of ST6Gal-I Downregulates BACE1 Expression and Suppresses Production of Aβ42 Plaques in Alzheimer’s Disease
Ablation of ST6Gal-I Downregulates BACE1 Expression and Suppresses Production of Aβ42 Plaques in Alzheimer’s Disease Open
View article: Proteomics Reveals Crosstalk between Calcium Disturbance and Multiple Stresses Facilitating Lethal Ventricular Arrhythmias-Sudden Cardiac Death Under the Co-Morbidity of Acute Myocardial Ischemia and Type Ii Diabetes Mellitus
Proteomics Reveals Crosstalk between Calcium Disturbance and Multiple Stresses Facilitating Lethal Ventricular Arrhythmias-Sudden Cardiac Death Under the Co-Morbidity of Acute Myocardial Ischemia and Type Ii Diabetes Mellitus Open
View article: The L1CAM‐positive extracellular vesicle‐based biomarker as a promising predictor of Parkinson's disease
The L1CAM‐positive extracellular vesicle‐based biomarker as a promising predictor of Parkinson's disease Open
Parkinson's disease (PD) is a multifaceted neurodegenerative disorder characterized by a prolonged prodromal phase followed by the onset of clinical motor symptoms. The development of reliable biomarkers for individuals at risk of developi…
View article: mROS‑calcium feedback loop promotes lethal ventricular arrhythmias and sudden cardiac death in early myocardial ischemia
mROS‑calcium feedback loop promotes lethal ventricular arrhythmias and sudden cardiac death in early myocardial ischemia Open
Lethal ventricular arrhythmia‑sudden cardiac death (LVA‑SCD) occurs frequently during the early stage of myocardial ischemia (MI). However, the mechanism underlying higher LVA‑SCD incidence is still poorly understood. The present study aim…
View article: Manufacturing-oriented topological design of CFRC structures with variable fiber volume and orientation
Manufacturing-oriented topological design of CFRC structures with variable fiber volume and orientation Open
Allowing freely steering fiber orientation, curvilinear fiber reinforced composite has much better load-bearing capacities than conventional straight-fiber composites. However, the uneven distribution of the fiber and the manufacturability…
View article: Serum proteomics reveals the proteomic characteristics involved in the progressive feature of acute ischemic stroke (AIS)
Serum proteomics reveals the proteomic characteristics involved in the progressive feature of acute ischemic stroke (AIS) Open
Background To distinguish acute progressive ischemic stroke (APIS) from acute non-progressive ischemic stroke (ANPIS) is clinically critical for the precise treatment and prevention of acute ischemic stroke (AIS) deterioration. Serum prote…