Mineon Park
YOU?
Author Swipe
View article: Single radiation exposure induces gut microbiota dysbiosis and decreases short-chain fatty acid metabolism and intestinal barrier integrity in mice
Single radiation exposure induces gut microbiota dysbiosis and decreases short-chain fatty acid metabolism and intestinal barrier integrity in mice Open
Ionizing radiation causes biological damage, including DNA damage, inflammation, and tissue homeostasis disruption. The gastrointestinal tract, which harbors diverse gut microbiota, is particularly susceptible to radiation-induced injury a…
View article: AZD 9668, a neutrophil elastase inhibitor, promotes wound healing in the irradiated skin by inhibiting NET-derived vascular dysfunction
AZD 9668, a neutrophil elastase inhibitor, promotes wound healing in the irradiated skin by inhibiting NET-derived vascular dysfunction Open
Despite the increasing awareness of the health risks associated with radiation exposure such as radiotherapy and accidents, effective treatments remain limited except for bone marrow damage. Radiation-induced skin damage is a critical conc…
View article: Combined Administration of Pravastatin and Metformin Attenuates Acute Radiation-Induced Intestinal Injury in Mouse and Minipig Models
Combined Administration of Pravastatin and Metformin Attenuates Acute Radiation-Induced Intestinal Injury in Mouse and Minipig Models Open
Radiation-induced gastrointestinal (GI) damage is one of the critical factors that serve as basis for the lethality of nuclear accidents or terrorism. Further, there are no Food and Drug Administration-approved agents available to mitigate…
View article: Drug Release from Thermo‐Responsive Polymer Brush Coatings to Control Bacterial Colonization and Biofilm Growth on Titanium Implants
Drug Release from Thermo‐Responsive Polymer Brush Coatings to Control Bacterial Colonization and Biofilm Growth on Titanium Implants Open
Despite decades of biomedical advances, the colonization of implant devices with bacterial biofilms is still a leading cause of implant failure. Clearly, new strategies and materials that suppress both initial and later stage bacterial col…
View article: A novel modified RANKL variant can prevent osteoporosis by acting as a vaccine and an inhibitor
A novel modified RANKL variant can prevent osteoporosis by acting as a vaccine and an inhibitor Open
Background The discovery of receptor activator of nuclear factor‐ĸB ligand (RANKL) as the final effector in the pathogenesis of osteoporosis has led to a better understanding of bone remodeling. When RANKL binds to its receptor (RANK), ost…
View article: RANKL Immunisation Inhibits Prostate Cancer Metastasis by Modulating EMT Through A RANKL-Dependent Pathway
RANKL Immunisation Inhibits Prostate Cancer Metastasis by Modulating EMT Through A RANKL-Dependent Pathway Open
Background: Prostate cancer (PCa) morbidity in the majority of patients is due to metastatic events, which are a clinical obstacle. Therefore, a better understanding of the mechanism underlying metastasis is imperative if we are to develop…
View article: RANKL Immunisation Inhibits Prostate Cancer Metastasis by Modulating EMT Through a RANKL-dependent Pathway
RANKL Immunisation Inhibits Prostate Cancer Metastasis by Modulating EMT Through a RANKL-dependent Pathway Open
Background: Prostate cancer (PCa) morbidity in the majority of patients is due to metastatic events, which are a clinical obstacle. Therefore, a better understanding of the mechanism underlying metastasis is imperative if we are to develop…
View article: Effect of CD133 overexpression on bone metastasis in prostate cancer cell line LNCaP
Effect of CD133 overexpression on bone metastasis in prostate cancer cell line LNCaP Open
Prostate cancer (PC) metastasizes to the bone, and a small number of cancer cells, described as cancer stem cells (CSCs), have the ability to differentiate into tumor cells. CSCs are responsible for tumor recurrence and metastases. In the …
View article: Regulation of Osteosclerosis by Inoculated Cd133<sup>+</sup> PC3 Cells in Bone‐marrow Microenvironmental Niches
Regulation of Osteosclerosis by Inoculated Cd133<sup>+</sup> PC3 Cells in Bone‐marrow Microenvironmental Niches Open
Bone is the most common site of prostate cancer (PC) metastasis. Studies suggest that cancer stem cells (CSCs) are associated with stemness characteristics, providing some support for the concept that CSCs act as osteosclerotic precursors …
View article: Microelectric Treatment by Transcutaneous Electrical Nerve Stimulation in a Rat Model of Acute Spinal Cord Injury
Microelectric Treatment by Transcutaneous Electrical Nerve Stimulation in a Rat Model of Acute Spinal Cord Injury Open
Study Design: Animal study
View article: Real-time<i>in vivo</i>imaging of metastatic bone tumors with a targeted near-infrared fluorophore
Real-time<i>in vivo</i>imaging of metastatic bone tumors with a targeted near-infrared fluorophore Open
Tumors of the prostate or breast are particularly likely to metastasize to the bone, and early diagnosis of metastatic bone tumors is important for designing an effective treatment strategy. Imaging modalities for the detection of bone met…