Long Chiau Ming
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View article: A comparative review of single-cell atlases: mapping cellular diversity across species and tissues
A comparative review of single-cell atlases: mapping cellular diversity across species and tissues Open
Single-cell sequencing (sc-seq) technologies have revolutionized biomedical research by enabling high-resolution analysis of cellular heterogeneity across multiple dimensions, including transcriptomics, epigenomics, and spatial profiling. …
View article: Continuity of Chronic Disease Care in Gaza: a Commentary on Health System Collapse and Humanitarian Imperatives
Continuity of Chronic Disease Care in Gaza: a Commentary on Health System Collapse and Humanitarian Imperatives Open
The 2023 Gaza conflict precipitated a collapse of essential health services, exposing the extreme fragility of chronic disease care in humanitarian crises. Non-communicable diseases (NCDs) account for more than 70% of deaths in Palestine, …
View article: The adherence–quality of life paradox in tuberculosis care after COVID-19: a cross-sectional study in Indonesia
The adherence–quality of life paradox in tuberculosis care after COVID-19: a cross-sectional study in Indonesia Open
Introduction Tuberculosis (TB) remains one of Indonesia’s most pressing public health challenges, particularly in the post-COVID-19 era. Medication adherence is widely considered critical to TB treatment success and is often linked to impr…
View article: Zebrafish Brain Regeneration as a Model for Neurorepair in Parkison’s Disease
Zebrafish Brain Regeneration as a Model for Neurorepair in Parkison’s Disease Open
Parkinson’s disease (PD) is the fastest-growing neurodegenerative disease in the world. Despite extensive research, its aetiology and pathogenesis remain poorly understood, often leading to delayed or missed diagnoses, especially in early-…
View article: Biological activities of Centaurium erythraea and its main chemotypes: menthol, carvacrol, and tricosane
Biological activities of Centaurium erythraea and its main chemotypes: menthol, carvacrol, and tricosane Open
Here, we investigated the antioxidant, antidiabetic, dermatoprotective, and antibacterial capacities of Centaurium erythraea essential oil (CEEO) and its major compounds namely menthol, carvacrol, and tricosane. The main findings revealed …
View article: Exploring the nutritional, cultural, and industrial significance of Metroxylon sagu
Exploring the nutritional, cultural, and industrial significance of Metroxylon sagu Open
Sago palm (Metroxylon sagu Rottb.) is a starch-producing plant with considerable potential for enhancing food security and sustainable development, particularly in Southeast Asia. Despite its high yield and adaptability to marginal environ…
View article: Unravelling Alpha-Mangostin as a Promising Anticancer Agent: An Overview of Therapeutic Effects, Molecular Mechanisms, and Strategies to Improve Treatment Outcomes
Unravelling Alpha-Mangostin as a Promising Anticancer Agent: An Overview of Therapeutic Effects, Molecular Mechanisms, and Strategies to Improve Treatment Outcomes Open
Cancer represents a significant global health concern, contributing to a high number of fatalities in the 21st century, with projections indicating a continuous spike in cancer cases. Although chemotherapy is an established cancer treatmen…
View article: Incorporating behavioural and psychological factors into cardiovascular disease risk prediction models: protocol for a systematic review
Incorporating behavioural and psychological factors into cardiovascular disease risk prediction models: protocol for a systematic review Open
Objectives This systematic review aims to: (1) evaluate how behavioural and psychological factors have been incorporated into cardiovascular disease (CVD) risk prediction models; (2) assess their impact on model performance metrics such as…
View article: Perceptions and Experiences of Indian Traditional Medicine Practitioners in Managing Epilepsy: A Qualitative Study in Malaysia
Perceptions and Experiences of Indian Traditional Medicine Practitioners in Managing Epilepsy: A Qualitative Study in Malaysia Open
This study aimed to explore the perceptions and clinical experiences of Indian traditional medicine, Ayurveda practitioners in Malaysia regarding the use of complementary and alternative medicine (CAM) in the treatment of epilepsy. An expl…
View article: Biotechnology and 3D printing in transforming prosthetic limb manufacturing for personalised healthcare
Biotechnology and 3D printing in transforming prosthetic limb manufacturing for personalised healthcare Open
The use of three-dimensional (3D) printing in the manufacturing of prosthetic limbs has become a revolutionary technology that presents new opportunities of customisation, affordability and accessibility. Conventional prosthetic production…
View article: BuShenFang Suppresses Tumor Growth and Induces Apoptosis in Colorectal Cancer Xenografts
BuShenFang Suppresses Tumor Growth and Induces Apoptosis in Colorectal Cancer Xenografts Open
Colorectal cancer (CRC) remains a major global health burden, necessitating alternative therapeutic approaches. Traditional Chinese Medicine (TCM), including BuShenFang (BSF), has demonstrated potential anti-CRC effects, yet its precise me…
View article: Stem Cell‐Based Cancer Therapies: A Commentary on Therapeutic Promise, Health Impacts and Translational Barriers
Stem Cell‐Based Cancer Therapies: A Commentary on Therapeutic Promise, Health Impacts and Translational Barriers Open
Stem cell-based cancer therapies offer novel mechanisms for tumour targeting, immune modulation and tissue repair, with applications from haematopoietic to induced pluripotent stem cells. While showing strong therapeutic promise, their cli…
View article: Obesity care knowledge and practice among primary care physicians in Klang valley: a cross-sectional study
Obesity care knowledge and practice among primary care physicians in Klang valley: a cross-sectional study Open
Background Obesity has become a public health concern as its prevalence has increased rapidly around the world, including Malaysia. Primary care physicians (PCPs) are the first point of contact for obese patients, playing a crucial role in…
View article: Exploring the relationship of complementary therapy use and medication adherence among patients with epilepsy
Exploring the relationship of complementary therapy use and medication adherence among patients with epilepsy Open
The findings highlight widespread use of CATs among PWE, often driven by cultural beliefs and perceived benefits. Thus, further research is warranted to explore integrative care models that ensure safe, coordinated epilepsy management.
View article: Effects of Bioactive Compounds on Autophagy: A Systematic Review
Effects of Bioactive Compounds on Autophagy: A Systematic Review Open
Autophagy, a crucial cellular process for maintaining homeostasis, plays a significant role in the degradation and recycling of cellular components. Dysregulation of autophagy has been implicated in numerous diseases, including neurodegene…
View article: Modulation of Wnt/β-Catenin Signaling Pathway by Bushenfang for Colorectal Tumor Inhibition in mice with Adenomatous Polyposis Coli Gene Mutation
Modulation of Wnt/β-Catenin Signaling Pathway by Bushenfang for Colorectal Tumor Inhibition in mice with Adenomatous Polyposis Coli Gene Mutation Open
Colorectal cancer (CRC) remains a major health concern worldwide, with current treatments associated with significant side effects and resistance. Traditional Chinese medicine (TCM), particularly BuShenFang (BSF), has shown potential as an…
View article: Improving Diabetes Care with the Omnipod <sup>→</sup> Automated Insulin System
Improving Diabetes Care with the Omnipod <sup>→</sup> Automated Insulin System Open
The Omnipod → , a tubeless automated insulin delivery system, presents itself as a compelling innovation in diabetes management. Initially developed to overcome the limitations of conventional insulin pumps, the closed-loop system of the O…
View article: Systematic review protocol for effectiveness and cost-effectiveness of non-surgical interventions to prevent diabetes progression in adults with prediabetes
Systematic review protocol for effectiveness and cost-effectiveness of non-surgical interventions to prevent diabetes progression in adults with prediabetes Open
Introduction Prediabetes (PD), defined by impaired glucose tolerance or impaired fasting glucose, represents a growing global health challenge, with a prevalence projected to increase substantially. PD is a critical intervention target bec…
View article: Review on 3D Printing Filaments Used in Fused Deposition Modeling Method for Dermatological Preparations
Review on 3D Printing Filaments Used in Fused Deposition Modeling Method for Dermatological Preparations Open
Three-dimensional printing, particularly Fused Deposition Modeling (FDM), has revolutionized dermatological drug delivery by offering the ability to create personalized and precise drug formulations. This technology enables the design of c…