Zhiming Li
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View article: Improvements in health-related quality of life (HRQoL) in the SUNMO study: Subcutaneous (SC) mosunetuzumab plus polatuzumab vedotin (Mosun-Pola) vs rituximab, gemcitabine and oxaliplatin (R-GemOx) in patients with relapsed/refractory (R/R) large B-cell lymphoma (LBCL) after at least one prior therapy
Improvements in health-related quality of life (HRQoL) in the SUNMO study: Subcutaneous (SC) mosunetuzumab plus polatuzumab vedotin (Mosun-Pola) vs rituximab, gemcitabine and oxaliplatin (R-GemOx) in patients with relapsed/refractory (R/R) large B-cell lymphoma (LBCL) after at least one prior therapy Open
Background: HRQoL is often impaired in pts with R/R LBCL (Abramson et al. ASH 2021). SUNMO (NCT05171647), a randomized Phase III study, compared Mosun-Pola vs R-GemOx in pts with R/R LBCL. Mosun-Pola significantly improved overall response…
View article: A phase I study of HDM2005, a ROR1 targeted antibody-drug conjugate (ADC), in patients with relapsed or refractory B-cell non-Hodgkin lymphoma (B-NHL) or classical Hodgkin lymphoma(cHL)
A phase I study of HDM2005, a ROR1 targeted antibody-drug conjugate (ADC), in patients with relapsed or refractory B-cell non-Hodgkin lymphoma (B-NHL) or classical Hodgkin lymphoma(cHL) Open
Background: The receptor tyrosine kinase-like orphan receptor 1 (ROR1) is a transmembrane protein that is overexpressed in multiple cancers, including lymphomas. HDM2005 is an antibody-drug conjugate comprising a humanized IgG1 monoclonal …
View article: Optimized Subgoal Generation in Hierarchical Reinforcement Learning for Coverage Path Planning
Optimized Subgoal Generation in Hierarchical Reinforcement Learning for Coverage Path Planning Open
Hierarchical Reinforcement Learning (HRL) for UAV Coverage Path Planning (CPP) is hindered by the “subgoal space explosion”, causing inefficient exploration. To address this, we propose a two-stage framework, Hierarchical Reinforcement Lea…
View article: The value of relative CT attenuation in predicting invasiveness in patients with T1-stage lung adenocarcinoma
The value of relative CT attenuation in predicting invasiveness in patients with T1-stage lung adenocarcinoma Open
In T1-stage LUAD, both lobe-normalized relative CT attenuation and nodule-specific absolute CT attenuation provide reliable predictors of invasiveness. However, relative CT values did not outperform absolute CT values in this study. Thus, …
View article: Rapid determination method of geothermal well spacing in the Rongdong area of the Xiong’an New Area
Rapid determination method of geothermal well spacing in the Rongdong area of the Xiong’an New Area Open
As a clean and renewable energy source, geothermal resources play an important role in achieving the goals of carbon peaking and carbon neutrality. The Xiong’an New Area is rich in geothermal resources; however, the rapid methods for deter…
View article: Towards Universal & Efficient Model Compression via Exponential Torque Pruning
Towards Universal & Efficient Model Compression via Exponential Torque Pruning Open
The rapid growth in complexity and size of modern deep neural networks (DNNs) has increased challenges related to computational costs and memory usage, spurring a growing interest in efficient model compression techniques. Previous state-o…
View article: Experimental Study on the Coupling of Freeze-Thaw Cycle and Chloride Corrosion of Alkali Slag Cementitious Materials
Experimental Study on the Coupling of Freeze-Thaw Cycle and Chloride Corrosion of Alkali Slag Cementitious Materials Open
Alkali-activated-slag cementitious material (AASCM) is distinguished by minimal energy consumption, reduced pollution, and superior mechanical properties; however, it is prone to issues such as susceptibility to cracking and inadequate fro…
Efficacy and safety of selinexor-based regimens as first-line treatments for elderly patients with diffuse large B-cell lymphoma: a real-world study Open
Purpose This study aimed to evaluate the efficacy and safety of selinexor-based regimens as first-line treatments for elderly patients with diffuse large B-cell lymphoma (DLBCL). Methods A retrospective analysis of 16 elderly patients with…
View article: Macroscopic and Microscopic Properties of Alkali-Activated Slag Recycled Cementitious Material
Macroscopic and Microscopic Properties of Alkali-Activated Slag Recycled Cementitious Material Open
Alkali-activated slag recycled cementitious material (ASRCM) has emerged as a sustainable construction material alternative due to its potential for industrial byproduct valorization and reduced carbon footprint. To study the effect of rec…
View article: Extranodal diffuse large B‐cell lymphoma: Clinical and molecular insights with survival outcomes from the multicenter EXPECT study
Extranodal diffuse large B‐cell lymphoma: Clinical and molecular insights with survival outcomes from the multicenter EXPECT study Open
Background Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of aggressive non‐Hodgkin's lymphoma with distinct clinical and molecular heterogeneity. DLBCL that arises in extranodal organs is particularly linked to poor prog…
View article: Green Multicomponent Alloys with Excellent Multifunctional and Mechanical Properties
Green Multicomponent Alloys with Excellent Multifunctional and Mechanical Properties Open
The global production and consumption of metals and alloys each year bring in an immense amount of metallic waste, placing a tremendous burden on resources and environments. Despite efforts made to recycle the waste materials by secondary …
View article: Tuning interfacial wettability in high‐entropy cemented carbides for enhanced mechanical performance
Tuning interfacial wettability in high‐entropy cemented carbides for enhanced mechanical performance Open
This study investigated three newly developed high‐entropy cemented carbides (HECCs) with high‐entropy carbides (HECs) as the hard phase and Co as the binder. Accordingly, the interfacial wettability between HECs and Co was tuned by the ch…
Two-gigapascal-strong ductile soft magnets Open
Soft magnetic materials (SMMs) are indispensable for electromechanical energy conversion in high-efficiency applications, but they are exposed to increasing mechanical loading conditions in electric motors due to higher rotational speeds. …
View article: Cortical structural network characteristics in non-cognitive impairment end-stage renal disease
Cortical structural network characteristics in non-cognitive impairment end-stage renal disease Open
Objective Explore alterations in topological features of gray matter volume (GMV) and structural networks in non-cognitive impairment end-stage renal disease (Non-CI ESRD). Materials and methods Utilizing graph theory, we collected structu…