Ming Jen Tan
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View article: Emerging Microbial and Enzymatic Approaches for Sustainable Antibiotic Biodegradation in Livestock Manure to Mitigate Water Pollution Risks
Emerging Microbial and Enzymatic Approaches for Sustainable Antibiotic Biodegradation in Livestock Manure to Mitigate Water Pollution Risks Open
The extensive use of antibiotics in animal husbandry leads to the release of unmetabolised residues and the dissemination of antimicrobial resistance genes (ARGs) in manure, posing environmental and public health challenges. Conventional t…
View article: YTHDF1 regulates YTHDF2 stability via m6A-dependent mechanisms in hepatocellular carcinoma: insights from in vitro, in vivo, and multi-cohort clinical studies
YTHDF1 regulates YTHDF2 stability via m6A-dependent mechanisms in hepatocellular carcinoma: insights from in vitro, in vivo, and multi-cohort clinical studies Open
YTHDF1 drives HCC progression through m6A-mediated stabilization of YTHDF2, revealing their functional synergy. Their combined spatial and expression profiles offer a superior prognostic biomarker, suggesting novel therapeutic targets.
View article: Effects of butyrylated high amylose maize starch (HAMSB) as an adjuvant for oral immunotherapy
Effects of butyrylated high amylose maize starch (HAMSB) as an adjuvant for oral immunotherapy Open
Background Oral immunotherapy (OIT) is an important treatment option for food allergy but achieving sustained unresponsiveness (SU) via OIT is challenging. Improving SU for OIT with adjuvants is of great interest but little progress has be…
View article: From Physicochemical Constraints to Clinical Prospects of Celastrol: Challenges and Nano Delivery Strategies
From Physicochemical Constraints to Clinical Prospects of Celastrol: Challenges and Nano Delivery Strategies Open
Celastrol (CeT) is the first pentacyclic triterpenoid compound isolated from the root bark of Tripterygium wilfordii. It has a broad spectrum of pharmacological activities, including anti-fibrosis, anti-tumor, anti-inflammation, immunomodu…
View article: In-process filament repair in 3D concrete printing with instance segmentation
In-process filament repair in 3D concrete printing with instance segmentation Open
3D Concrete Printing (3DCP) stands as an automated method using robotics to construct concrete structures layer by layer, offering time efficiency, cost savings, and improved safety. Despite its practical relevance, on-site operators are s…
View article: Construction Scheme Effects on Deformation Controls for Open-Top UBITs Underpassing Existing Stations
Construction Scheme Effects on Deformation Controls for Open-Top UBITs Underpassing Existing Stations Open
Urban rail transit networks’ rapid expansions have led to increasing intersections between existing and new lines, particularly in dense urban areas where new stations must underpass existing infrastructure at zero distance. Deformation co…
View article: RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma
RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma Open
The identification of predictive markers to determine the premetastatic phase before metastasis is critical for developing effective strategies for early detection and prevention. By applying the dynamic network biomarker (DNB) approach to…
View article: Accuracy and hallucination of DeepSeek and ChatGPT in scientific figure interpretation and reference retrieval
Accuracy and hallucination of DeepSeek and ChatGPT in scientific figure interpretation and reference retrieval Open
Artificial intelligence-based large language models (AI-LLMs) are increasingly used in biomedical research, but concerns remain regarding their accuracy and reliability, particularly in interpreting scientific data and generating reference…
View article: Effect of surface defect characteristics on the fatigue life of well-testing steel wires
Effect of surface defect characteristics on the fatigue life of well-testing steel wires Open
This paper introduces a well-testing steel-wire fatigue testing machine that simulates the stress conditions encountered by steel wires in various operational scenarios. Using this machine, fatigue life assessments were conducted on steel …
View article: Significant up-regulation of Toll-like receptor (TLR) signaling pathway in Epstein-Barr virus-associated gastric cancer
Significant up-regulation of Toll-like receptor (TLR) signaling pathway in Epstein-Barr virus-associated gastric cancer Open
Briefly, this study revealed a distinct pattern of activation of the TLR signaling pathway in EBVaGCs which can be seen as a specific feature of molecular pathology in the disease. This feature characterizes the disease as a distinct subty…
View article: [Performance of multi-modality and multi-classifier fusion models for predicting radiation-induced oral mucositis in patients with nasopharyngeal carcinoma].
[Performance of multi-modality and multi-classifier fusion models for predicting radiation-induced oral mucositis in patients with nasopharyngeal carcinoma]. Open
Compared with each of the individual classifiers, the multimodal multi-classifier fusion algorithm combining clinical and dosimetric modalities demonstrates superior performance in predicting the incidence of severe RIOM in NPC patients fo…
View article: Assessment of Large Language Models (LLMs) in decision-making support for gynecologic oncology
Assessment of Large Language Models (LLMs) in decision-making support for gynecologic oncology Open
LLMs, especially GemAdv, show potential in supporting clinical practice by providing accurate, consistent, and relevant information for gynecologic cancer. However, further refinement is needed for more complex scenarios. This study highli…
View article: Carbon capture and sequestration with in-situ CO2 and steam integrated 3D concrete printing
Carbon capture and sequestration with in-situ CO2 and steam integrated 3D concrete printing Open
Profound reliance of the building and construction sector on cement exacerbates its immense carbon footprint, accounting for a substantial portion of worldwide emissions. In this paper, we investigate the possibilities of in-situ carbon ca…
View article: 3D Cementitious composites printing with pretreated recycled crumb rubber: mechanical and acoustic insulation properties
3D Cementitious composites printing with pretreated recycled crumb rubber: mechanical and acoustic insulation properties Open
Cementitious materials incorporating recycled crumb rubber have become a common sustainable resolution in diverse building environments to achieve various functions in terms of lightweight, ductility, as well as energy absorption. This stu…
View article: Sustainable Support Material for Overhang Printing in 3D Concrete Printing Technology
Sustainable Support Material for Overhang Printing in 3D Concrete Printing Technology Open
The advantage of 3DCP technologies is the ability to fabricate free-form structures. However, printing openings in concrete structures are limited by the presence of overhanging sections. While various 3D printing and additive manufacturin…
View article: Evaluation of 3D robotic spray parameters on the performance of the developed sensing functional cementitious coating
Evaluation of 3D robotic spray parameters on the performance of the developed sensing functional cementitious coating Open
This study explores the innovative use of 3D robotic spray for applying self-sensing cementitious coating, emphasising its potential for multifunctional smart concrete applications. The effects of spray parameters on the performance of sel…
View article: Potential of carbon dioxide spraying on the properties of 3D concrete printed structures
Potential of carbon dioxide spraying on the properties of 3D concrete printed structures Open
Achieving net carbon neutrality is a global goal toward mitigating climate change presumed consequences. The building and construction sector, responsible for approximately 40 % of greenhouse gas emissions, requires innovative zero-carbon …
View article: Axial performances of the steel rebar reinforced column confined by the steel cable reinforced 3D concrete printing permanent formwork
Axial performances of the steel rebar reinforced column confined by the steel cable reinforced 3D concrete printing permanent formwork Open
Among reinforcement methods for 3D concrete printing (3DCP) structures, steel cable reinforcement and reinforced concrete confined by 3DCP formwork (RC-3DPF) methods offer high design freedom and automation. However, the former lacks reinf…
View article: Characteristics, clinical significance, and cancer immune interactions of lipid metabolism in prostate cancer
Characteristics, clinical significance, and cancer immune interactions of lipid metabolism in prostate cancer Open
Prostate cancer (PCa); lipid metabolism; cancer immune; RNA sequencing (RNA-seq).
View article: 3D‐Printed Mechano‐Optic Force Sensor for Soft Robotic Gripper Enabled by Programmable Structural Metamaterials
3D‐Printed Mechano‐Optic Force Sensor for Soft Robotic Gripper Enabled by Programmable Structural Metamaterials Open
Rapid deployment of automation in today's world has opened up exciting possibilities in the realm of design and fabrication of soft robotic grippers endowed with sensing capabilities. Herein, a novel design and rapid fabrication by 3D prin…
View article: Does Focal Kyphotic Deformity at Non‐responsible Levels Affect the Outcomes of Anterior Cervical Decompression and Fusion?
Does Focal Kyphotic Deformity at Non‐responsible Levels Affect the Outcomes of Anterior Cervical Decompression and Fusion? Open
Objective Focal cervical kyphotic deformity (FCK) without neurologic compression is not uncommon in patients with cervical spondylotic myelopathy (CSM) who underwent anterior cervical decompression and fusion (ACDF) surgery. It remains unc…
View article: Analysis of current situation and future development trend of national carbon market construction under the background of Energy Internet
Analysis of current situation and future development trend of national carbon market construction under the background of Energy Internet Open
The Energy Internet is an important technical and institutional support to expand the coverage of carbon trading and reduce transaction costs. The carbon trading system is an important financial and marketbased means to promote the low-car…