Min Yang
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View article: Tangshen Formula Ameliorates Diabetic Nephropathy by Suppressing Soluble Epoxide Hydrolase Activity to Enhance IRS2-Mediated PI3K/AKT Signaling
Tangshen Formula Ameliorates Diabetic Nephropathy by Suppressing Soluble Epoxide Hydrolase Activity to Enhance IRS2-Mediated PI3K/AKT Signaling Open
Background: Diabetic nephropathy (DN), a leading cause of end-stage renal disease, demands novel therapeutic strategies. This study investigated the ability of Tangshen formula (TSF) to modulate DN via a renoprotective mechanism involving …
View article: Agroforestry buffers drought stress by enhancing hydrological redistribution in dryland apple orchards
Agroforestry buffers drought stress by enhancing hydrological redistribution in dryland apple orchards Open
Water scarcity driven by intensifying drought poses a growing threat to agricultural productivity and ecosystem stability in drylands. Agroforestry systems, recognized as climate-resilient strategies, mitigate water stress through mechanis…
View article: Anion Shielding in Nb‐WO <sub>3</sub> /WS <sub>2</sub> Heterostructures: A Strategy for Efficient and Corrosion‐Resistant Seawater Electrolysis
Anion Shielding in Nb‐WO <sub>3</sub> /WS <sub>2</sub> Heterostructures: A Strategy for Efficient and Corrosion‐Resistant Seawater Electrolysis Open
Seawater electrolysis is a promising route for sustainable hydrogen production, but chloride‐induced corrosion severely limits its practicality. Here, a dual‐modulated Nb‐WO 3 /WS 2 heterostructure electrocatalyst that simultaneously enhan…
View article: Development and validation of a deep learning model for automatic severity grading of hip osteoarthritis: a multi-center study
Development and validation of a deep learning model for automatic severity grading of hip osteoarthritis: a multi-center study Open
The developed model enables automatic and objective assessment of HOA severity using KL grading across diverse populations and imaging conditions. This tool shows potential to support disease monitoring, and large-scale epidemiologic resea…
View article: Muscle Fibers, Free Amino Acids, and Enhanced Mitochondrial Function Explain the Unique Meat Quality of Tibetan Pigs
Muscle Fibers, Free Amino Acids, and Enhanced Mitochondrial Function Explain the Unique Meat Quality of Tibetan Pigs Open
The mechanistic underlying the favorable meat quality of Tibetan pigs has not been fully elucidated. This study integrated flavor chemistry, histomorphology, and proteomics to explore the structural and molecular features of their meat. Lo…
View article: Characterization and Biological Characteristics of Alternaria, Botryosphaeria, Pestalotiopsis, and Trichothecium Species Associated with Postharvest Loquat Fruit Rot in Yunnan, China
Characterization and Biological Characteristics of Alternaria, Botryosphaeria, Pestalotiopsis, and Trichothecium Species Associated with Postharvest Loquat Fruit Rot in Yunnan, China Open
Postharvest diseases caused by various fungal pathogens pose a significant threat to fruit quality, storage, and market value, making their identification and biological characterization essential for effective management strategies. This …
View article: Preparation of ZnCl2-Activated Magnetic Biochar and Its Performance in Removing Hexavalent Chromium from Water
Preparation of ZnCl2-Activated Magnetic Biochar and Its Performance in Removing Hexavalent Chromium from Water Open
Magnetic biochar (Zn/Fe-BC) was prepared from jujube branches via an impregnation pyrolysis–coprecipitation technique to eliminate Cr(VI) from water. ZnFe2O4 was introduced through ZnCl2-based impregnation and pyrolysis, which can regulate…
View article: Resin Glycosides with α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitory Activities from the Seeds of Cuscuta japonica
Resin Glycosides with α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitory Activities from the Seeds of Cuscuta japonica Open
In the present study, seven previously undescribed resin glycosides, designated cusponins I-VII (1–7), together with one known analog (8), were isolated from the seeds of Cuscuta japonica, a traditional medicine used in China. Structural e…
View article: Aptamer based lateral flow biosensor for rapid detection of largemouth bass virus
Aptamer based lateral flow biosensor for rapid detection of largemouth bass virus Open
The disease caused by Largemouth bass virus (LMBV) is one of the most serious viral diseases that threaten the development of largemouth bass industry. Point-of-Care testing of LMBV infection is crucial to prevent and control disease. Here…
View article: Functional Response, Interference, and Predation Efficiency of Diomus guilavoguii (Coleoptera: Coccinellidae) on Paracoccus marginatus (Hemiptera: Pseudococcidae)
Functional Response, Interference, and Predation Efficiency of Diomus guilavoguii (Coleoptera: Coccinellidae) on Paracoccus marginatus (Hemiptera: Pseudococcidae) Open
Paracoccus marginatus (Hemiptera: Pseudococcidae) poses a significant threat to over 200 plant species, severely impacting agricultural productivity. Diomus guilavoguii (Coleoptera: Coccinellidae) is a natural predator of P. marginatus. To…
View article: The impact of kinetic and global effects on ballooning 2nd stable pedestals of conventional and low aspect ratio tokamaks
The impact of kinetic and global effects on ballooning 2nd stable pedestals of conventional and low aspect ratio tokamaks Open
The EPED model [P.B. Snyder et al 2011 Nucl. Fusion 51 103016] had success describing the pedestals of the Type-I ELM and QH-mode operations in conventional tokamaks, by combining kinetic ballooning mode (KBM) and peeling-ballooning (PB) c…
View article: Nonpharmacologic treatment for elderly with constipation: a systematic review and meta-analysis
Nonpharmacologic treatment for elderly with constipation: a systematic review and meta-analysis Open
Objective This study evaluated the efficacy and safety of non-pharmacological interventions such as acupuncture, abdominal massage, ear acupoints, probiotics, and dietary fiber in the treatment of constipation in the elderly. Methods Rando…
View article: Correction: Identification of the AKCDPK gene family and AkCDPK15 functional analysis under drought and salt stress
Correction: Identification of the AKCDPK gene family and AkCDPK15 functional analysis under drought and salt stress Open
[This corrects the article DOI: 10.1371/journal.pone.0325453.].
View article: Retrospective analysis of the clinical effect of spinal cord stimulation in the treatment of painful diabetic peripheral neuropathy
Retrospective analysis of the clinical effect of spinal cord stimulation in the treatment of painful diabetic peripheral neuropathy Open
Introduction The aim of this study was to evaluate the clinical outcomes of spinal cord stimulation (SCS) in patients with painful diabetic peripheral neuropathy (PDPN). Materials and methods Ninety-two patients underwent permanent SCS imp…
View article: A phosphorylation switch in the Mediator MED15 controls cellular senescence and cognitive decline
A phosphorylation switch in the Mediator MED15 controls cellular senescence and cognitive decline Open
A hallmark of aging is chronic systemic inflammation, which is exacerbated by the hypersecretory aging phenotype known as the senescence-associated secretory phenotype (SASP). How the SASP is initiated to accelerate tissue inflammation and…
View article: RpNGS: an automated platform for pathogen identification and monitoring in clinical metagenomics data
RpNGS: an automated platform for pathogen identification and monitoring in clinical metagenomics data Open
Background The capacity of metagenomic sequencing-based diagnostics to fully identify infections have made them useful instruments in clinical practice. We introduce an interactive platform that runs on a local server-class hardware resour…
View article: Climate‐Dependent Hydrogen Isotopic Offset of Stem Water and Its Effect on Quantification of Plant Water Sources
Climate‐Dependent Hydrogen Isotopic Offset of Stem Water and Its Effect on Quantification of Plant Water Sources Open
Increasing evidence reports hydrogen isotopic offset (HIO) between plant stem and source soil water, which introduces considerable uncertainties in estimating plant water sources. However, it remains unknown how HIO varies along precipitat…
View article: LTGS-Net: Local Temporal and Global Spatial Network for Weakly Supervised Video Anomaly Detection
LTGS-Net: Local Temporal and Global Spatial Network for Weakly Supervised Video Anomaly Detection Open
Video anomaly detection has an important application value in the field of intelligent surveillance; however, due to the problems of sparse anomaly events and expensive labeling, it has made weakly supervised methods a research hotspot. Mo…
View article: Multi-Objective Vibration Control of a Vehicle-Track-Bridge Coupled System Using Tuned Inerter Dampers Based on the FE-SEA Hybrid Method
Multi-Objective Vibration Control of a Vehicle-Track-Bridge Coupled System Using Tuned Inerter Dampers Based on the FE-SEA Hybrid Method Open
To address the adverse effects of Tuned Inertia Dampers (TIDs) on track slab vibrations while controlling high-frequency rail vibrations, a hybrid Finite Element-Statistical Energy Analysis (FE-SEA) method is developed for modeling the veh…
View article: High-fat diet increases circulating palmitic acid produced by gut Bacteroides thetaiotaomicron to promote thrombosis
High-fat diet increases circulating palmitic acid produced by gut Bacteroides thetaiotaomicron to promote thrombosis Open
Circulating palmitic acid (PA) is generally considered to be provided from diets and endogenous synthesis and is adversely correlated with cardiovascular disease (CVD). It is unknown, however, if gut microbiota modulates circulating PA and…
View article: Exploring the anti-inflammatory mechanism of geniposide in rheumatoid arthritis via network pharmacology and experimental validation
Exploring the anti-inflammatory mechanism of geniposide in rheumatoid arthritis via network pharmacology and experimental validation Open
Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects millions worldwide, characterized by joint pain, swelling, and functional impairment. Current treatments like Non-steroidal anti-inflammatory drugs (NSAIDs), corticoste…