Explanipedia

Correction: A highly efficient heterologous expression platform to facilitate the production of microbial natural products in Streptomyces Open

Xiuling Wang, Ping Lin, Qiyao Shen, Xueyan Feng, Shouying Xu , et al. · 2025

A highly efficient heterologous expression platform to facilitate the production of microbial natural products in Streptomyces Open

Xiuling Wang, Ping Lin, Qiyao Shen, Xueyan Feng, Shouying Xu , et al. · 2025

We demonstrated that our Micro-HEP system enables the efficient expression of foreign BGCs, facilitating the discovery of new NPs and increasing yields.

De novo discovery of a molecular glue–like macrocyclic peptide that induces MCL1 homodimerization Open

Fengwei Li, Mengmeng Zhang, Chao Liu, Jie Cheng, Yawen Yang , et al. · 2025

Macrocyclic peptides have emerged as promising drug candidates, filling the gap between small molecules and large biomolecules in drug discovery. The antiapoptotic protein myeloid cell leukemia 1 (MCL1) is crucial for numerous cancers, yet…

Simple Carbazole-based Bipolar Host Materials for Blue Phosphorescent Organic Light-Emitting Devices with Negligible Efficiency Roll-offs Open

Hong Huang, Tao Hua, Nengquan Li, Manli Huang, You‐Ming Zhang , et al. · 2025

Isolation, Characterization, and Genome Engineering of a Lytic Pseudomonas aeruginosa Phage Open

Xiaomei Cong, Shuang Zhao, Qing Zhang, Shuo Liu, You‐Ming Zhang , et al. · 2024

Antibiotic-resistant bacterial infections have become one of the leading causes of human mortality. Bacteriophages presented great potential for combating antibiotic-resistant infections in the post-antibiotic era due to their high host sp…

CCDC 1553559: Experimental Crystal Structure Determination Open

Qi Lin, Lu Liu, Feng Zheng, Peng‐Peng Mao, You‐Ming Zhang , et al. · 2024

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

Guest-Induced Supramolecular Helices and Its’ Application in L-Arg Detection and L-Arg Controlled Reversible Morphology Open

Tai‐Bao Wei, Jian‐Peng Hu, Guoyan Liang, Qi Lin, Hong Yao , et al. · 2024

Ribosomal translation of fluorinated non-canonical amino acids for <i>de novo</i> biologically active fluorinated macrocyclic peptides Open

Junjie Wu, Y. Wang, Wenfeng Cai, Danyan Chen, Xiangda Peng , et al. · 2024

Fluorinated non-canonical amino acids were ribosomally translated, allowing identification of fluorinated macrocyclic peptides with strong binding to EphA2 and broad-spectrum activity against Gram-negative bacteria by targeting the BAM com…

CCDC 2258189: Experimental Crystal Structure Determination Open

Tao Hua, Nengquan Li, Zhongyan Huang, You‐Ming Zhang, Wang Lian , et al. · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 2258188: Experimental Crystal Structure Determination Open

Tao Hua, Nengquan Li, Zhongyan Huang, You‐Ming Zhang, Wang Lian , et al. · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

Influence of two kinds of clearance joints on the dynamics of planar mechanical system based on a modified contact force model Open

Haiyan Tan, Li Li, Qiang Huang, Zhuoda Jiang, Qingxiang Li , et al. · 2023

This study takes the slider-crank mechanism with revolute joint and translational joint as the research object and studies the contact force model of the clearance joint and the influence of the hybrid clearance joints on the nonlinear dyn…

CCDC 2265589: Experimental Crystal Structure Determination Open

Bingbing Shi, Peng Qin, Weichun Li, Hua Feng, Yi Zhou , et al. · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

PepScaf: Harnessing Machine Learning with In Vitro Selection toward De Novo Macrocyclic Peptides against IL-17C/IL-17RE Interaction Open

Silong Zhai, Yahong Tan, Chengyun Zhang, Christopher J. Hipolito, Lulu Song , et al. · 2023

The combination of library-based screening and artificial intelligence (AI) has been accelerating the discovery and optimization of hit ligands. However, the potential of AI to assist in de novo macrocyclic peptide ligand discovery has yet…

CCDC 2090760: Experimental Crystal Structure Determination Open

Qiyao Shen, Guangzhi Dai, Aiying Li, Yang Liu, Guannan Zhong , et al. · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 2090762: Experimental Crystal Structure Determination Open

Qiyao Shen, Guangzhi Dai, Aiying Li, Yang Liu, Guannan Zhong , et al. · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 2090761: Experimental Crystal Structure Determination Open

Qiyao Shen, Guangzhi Dai, Aiying Li, Yang Liu, Guannan Zhong , et al. · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

Systematic identification of endogenous strong constitutive promoters from the diazotrophic rhizosphere bacterium Pseudomonas stutzeri DSM4166 to improve its nitrogenase activity Open

Guangle Yu, Xiaochen Li, Qiuyue Duan, Jun Fu, You‐Ming Zhang , et al. · 2023

Consequence of Competition between Type I and Ii Methanotrophs Determines Methane Oxidation and Assimilation in Rice Paddy Fields Open

Shengmeng Zheng, Shaohong Deng, Chong Ma, Yinhang Xia, Hang Qiao , et al. · 2023

Consequence of Competition between Type I and Ii Methanotrophs Determines Methane Oxidation and Assimilation in Rice Paddy Fields Open

Shengmeng Zheng, Shaohong Deng, Chong Ma, Yinhang Xia, Hang Qiao , et al. · 2023

Consequence of Competition between Type I and Ii Methanotrophs Determines Methane Oxidation and Assimilation in Rice Paddy Fields Open

Shengmeng Zheng, Shaohong Deng, Chong Ma, Yinhang Xia, Hang Qiao , et al. · 2023

Constructing a Novel “Turn-On” Fluorescent Sensor Based on Phenazine Macrocycle Through Halogen Bond Interaction for the Naked-Eye Detection of Phenylenediamine Isomers Open

Yu‐Xin Che, Jian‐Peng Hu, Shao‐Ping Tao, Qi Lin, Hong Yao , et al. · 2023

CCDC 2041062: Experimental Crystal Structure Determination Open

Tai‐Bao Wei, Li‐Rong Dang, Jian‐Peng Hu, Yu Jia, Qi Lin , et al. · 2022

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

Unsupported MoS2-Based Catalysts for Bio-Oil Hydrodeoxygenation: Recent Advances and Future Perspectives Open

Jing Cao, You‐Ming Zhang, Li Wang, Cen Zhang, Congshan Zhou · 2022

In recent years, unsupported MoS 2 -based catalysts have been reported as promising candidates in the hydrodeoxygenation (HDO) of bio-oil. However, preparing MoS 2 -based catalysts with both high activity and good stability for HDO reactio…

CCDC 2142004: Experimental Crystal Structure Determination Open

Bingbing Shi, Peng Qin, Yongping Chai, Wenjuan Qu, Liqing Shangguan , et al. · 2022

Comparison of Co-Mo-S and Remote Control Model for Designing Efficient Co-Doped Mos2 Hydrodeoxygenation Catalysts Open

Jing Cao, You‐Ming Zhang, Xinyi Liu, Cen Zhang, Zelong Li · 2022

Rationally Designed a Silent Aie Oxidation Platform Based on Pillar[5]Arene for H2po4-And VC Sensor Open

Jianpeng Hu, Tai‐Bao Wei, Qi Lin, Hong Yao, You‐Ming Zhang · 2022

Merging the Versatile Functionalities of Boronic Acid with Peptides Open

Yahong Tan, Junjie Wu, Lulu Song, Mengmeng Zhang, Christopher J. Hipolito , et al. · 2021

Peptides inherently feature the favorable properties of being easily synthesized, water-soluble, biocompatible, and typically non-toxic. Thus, boronic acid has been widely integrated with peptides with the goal of discovering peptide ligan…

A metamaterial-free fluid-flow cloak Open

Fuyang Tay, You‐Ming Zhang, Hongyi Xu, Honghui Goh, Yu Luo , et al. · 2021

The model of ideal fluid flow around a cylindrical obstacle exhibits a long-established physical picture, where originally straight streamlines are deflected over the whole space by the obstacle. Inspired by transformation optics and metam…

High Performance Near-Infrared Emitters with Methylated Triphenylamine and Thiadiazolo[3,4-g]quinoxaline-Based Fluorophores Open

You‐Ming Zhang, Chengjun Wu, Minrong Zhu, Jingsheng Miao · 2021

Three near-infrared emitters (2TPA-QBT, 2MeTPA-BT and TPA-QBT-MeTPA) were rationally designed and synthesized. Density functional theory (DFT) and time-dependent density functional theory (TDDFT) calculations showed that the introduction o…

The inaugural Editorial of Engineering Microbiology Open

You‐Ming Zhang · 2021

You‐Ming Zhang YOU? Author Swipe