Min Peng
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View article: Multidimensional Regulatory Mechanisms of LvChia2 on Growth in the Pacific White Shrimp (Litopenaeus vannamei)
Multidimensional Regulatory Mechanisms of LvChia2 on Growth in the Pacific White Shrimp (Litopenaeus vannamei) Open
Background: As a globally significant aquaculture species, elucidating the molecular mechanisms underlying the regulation of the Pacific White Shrimp (Litopenaeus vannamei) growth holds substantial scientific and industrial value. This stu…
View article: Novel Compound Heterozygous Variants in <scp><i>ZNF526</i></scp> Causing Dentici‐Novelli Neurodevelopmental Syndrome: A Case Report and Literature Review
Novel Compound Heterozygous Variants in <span><i>ZNF526</i></span> Causing Dentici‐Novelli Neurodevelopmental Syndrome: A Case Report and Literature Review Open
Background The ZNF526 gene encodes a ubiquitously expressed Kruppel‐type zinc finger protein crucial in transcriptional regulation. Recent studies suggest that biallelic pathogenic variants in ZNF526 may lead to Dentici‐Novelli neurodevelo…
View article: Construction of silver-coated high translucent zirconia implanting abutment material and its property of antibacterial
Construction of silver-coated high translucent zirconia implanting abutment material and its property of antibacterial Open
High translucent zirconia (HTZ) has excellent mechanical properties, biocompatibility, and good semi-translucency making it an ideal material for aesthetic anterior dental implant abutments without antibacterial properties. In the oral env…
View article: Dual FGFR and VEGFR inhibition synergistically restrain hexokinase 2-dependent lymphangiogenesis and immune escape in intrahepatic cholangiocarcinoma
Dual FGFR and VEGFR inhibition synergistically restrain hexokinase 2-dependent lymphangiogenesis and immune escape in intrahepatic cholangiocarcinoma Open
Background Therapies for cholangiocarcinoma are largely limited and ineffective. Herein, we examined the role of the FGF and VEGF pathways in regulating lymphangiogenesis and PD-L1 expression in intrahepatic cholangiocarcinoma (iCCA). Meth…
View article: Supplementary Data from Replication Gaps Underlie BRCA Deficiency and Therapy Response
Supplementary Data from Replication Gaps Underlie BRCA Deficiency and Therapy Response Open
Methods and references
View article: Data from Replication Gaps Underlie BRCA Deficiency and Therapy Response
Data from Replication Gaps Underlie BRCA Deficiency and Therapy Response Open
Defects in DNA repair and the protection of stalled DNA replication forks are thought to underlie the chemosensitivity of tumors deficient in the hereditary breast cancer genes BRCA1 and BRCA2 (BRCA). Challenging this assumption are recent…
View article: Supplementary Data from Replication Gaps Underlie BRCA Deficiency and Therapy Response
Supplementary Data from Replication Gaps Underlie BRCA Deficiency and Therapy Response Open
Methods and references
View article: Supplementary Figure Legends from Replication Gaps Underlie BRCA Deficiency and Therapy Response
Supplementary Figure Legends from Replication Gaps Underlie BRCA Deficiency and Therapy Response Open
Supplemental Figure Legends
View article: Data from Replication Gaps Underlie BRCA Deficiency and Therapy Response
Data from Replication Gaps Underlie BRCA Deficiency and Therapy Response Open
Defects in DNA repair and the protection of stalled DNA replication forks are thought to underlie the chemosensitivity of tumors deficient in the hereditary breast cancer genes BRCA1 and BRCA2 (BRCA). Challenging this assumption are recent…
View article: Supplementary Data from Replication Gaps Underlie BRCA Deficiency and Therapy Response
Supplementary Data from Replication Gaps Underlie BRCA Deficiency and Therapy Response Open
Supplemental Figures 1-6. Figure S1: BRCA-deficient cancer cells fail to restrain replication in the presence of stress and ssDNA gaps develop. Figure S2: Replication restraint, depletion, and PDX controls. Figure S3: Depletion of SMARCAL1…
View article: Supplementary Data from Replication Gaps Underlie BRCA Deficiency and Therapy Response
Supplementary Data from Replication Gaps Underlie BRCA Deficiency and Therapy Response Open
Supplemental Figures 1-6. Figure S1: BRCA-deficient cancer cells fail to restrain replication in the presence of stress and ssDNA gaps develop. Figure S2: Replication restraint, depletion, and PDX controls. Figure S3: Depletion of SMARCAL1…
View article: Supplementary Figure Legends from Replication Gaps Underlie BRCA Deficiency and Therapy Response
Supplementary Figure Legends from Replication Gaps Underlie BRCA Deficiency and Therapy Response Open
Supplemental Figure Legends
View article: Supplementary Figure Legend from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Supplementary Figure Legend from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation Open
PDF file - 103K
View article: Supplementary Table 1 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Supplementary Table 1 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation Open
PDF file - 43K, Supplemental Table 1. FANCJ suppresses UV-induced mutations at the HPRT locus.
View article: Supplementary Figure 8 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Supplementary Figure 8 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation Open
PDF file - 119K, Supplemental Figure 8. Ectopic expression of catalytic inactive FANCJK52R disrupts clearance of UV induced lesions in U2OS cells
View article: Supplementary Figure 6 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Supplementary Figure 6 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation Open
PDF file - 106K, Supplemental Figure 6. FANCJ deficient cells are sensitive to DNA interstrand crosslinking agents and FANCJ suppresses UV-induced mutations
View article: Supplementary Figure 4 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Supplementary Figure 4 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation Open
PDF file - 68K, Supplemental Figure 4. FANCJ and MMR function in a common pathway for RPA phosphorylation and 6-4 Photoproduct elimination, but not for gap repair.
View article: Supplementary Figure 5 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Supplementary Figure 5 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation Open
PDF file - 29K, Supplemental Figure 5. FANCJ precipitates with UV modified PCNA and CPD from chromatin extracts.
View article: Supplementary Figure 8 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Supplementary Figure 8 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation Open
PDF file - 119K, Supplemental Figure 8. Ectopic expression of catalytic inactive FANCJK52R disrupts clearance of UV induced lesions in U2OS cells
View article: Supplementary Figure Legend from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Supplementary Figure Legend from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation Open
PDF file - 103K
View article: Supplementary Figure 4 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Supplementary Figure 4 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation Open
PDF file - 68K, Supplemental Figure 4. FANCJ and MMR function in a common pathway for RPA phosphorylation and 6-4 Photoproduct elimination, but not for gap repair.
View article: Supplementary Figure 9 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Supplementary Figure 9 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation Open
PDF file - 88K, Supplemental Figure 9. FANCJ expression promotes UV induced GFP-polh foci formation in U2OS cells.
View article: Supplementary Figure 3 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Supplementary Figure 3 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation Open
PDF file - 228K, Supplemental Figure 3. FANCJ localizes to UV induced LUDs predominantly in S-Phase and contributes to the UV induced checkpoint
View article: Supplementary Figure 1 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Supplementary Figure 1 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation Open
PDF file - 151K, Supplemental Figure 1. FANCJ is recruited to sites of UV-induced damage in an NER dependent manner
View article: Supplementary Figure 6 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Supplementary Figure 6 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation Open
PDF file - 106K, Supplemental Figure 6. FANCJ deficient cells are sensitive to DNA interstrand crosslinking agents and FANCJ suppresses UV-induced mutations
View article: Supplementary Figure 9 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Supplementary Figure 9 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation Open
PDF file - 88K, Supplemental Figure 9. FANCJ expression promotes UV induced GFP-polh foci formation in U2OS cells.
View article: Supplementary Figure 2 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Supplementary Figure 2 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation Open
PDF file - 260K, Supplemental Figure 2. MMR localizes FANCJ to UV induced LUDs
View article: Supplementary Figure 2 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation
Supplementary Figure 2 from FANCJ Localization by Mismatch Repair Is Vital to Maintain Genomic Integrity after UV Irradiation Open
PDF file - 260K, Supplemental Figure 2. MMR localizes FANCJ to UV induced LUDs