Min Bao
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View article: Efficient stem cell-derived mouse embryo models for environmental studies
Efficient stem cell-derived mouse embryo models for environmental studies Open
Blastoids are stem cell-derived structures that mimic natural blastocysts by incorporating all three lineages: trophectoderm, epiblast, and primitive endoderm. However, current methods often yield incomplete structures that fail to cavitat…
View article: A multistage research on factors influencing and active learning intervention on health literacy of community-residing elderly adults in Nanjing
A multistage research on factors influencing and active learning intervention on health literacy of community-residing elderly adults in Nanjing Open
The trial has been retrospectively registered on April 8, 2025, at the Chinese Clinical Trial Registry (ChiCTR2500100396|| http://www.chictr.org.cn/ ), which is a primary registry of the International Clinical Trial Registry Platform of th…
View article: de Winter electrocardiogram pattern evolving into Wellens electrocardiogram pattern in post-percutaneous coronary intervention therapy: a case report
de Winter electrocardiogram pattern evolving into Wellens electrocardiogram pattern in post-percutaneous coronary intervention therapy: a case report Open
Background The de Winter electrocardiogram (ECG) pattern and Wellens ECG pattern are rare but critical ECG findings, often considered high-risk equivalents of ST-segment elevation myocardial infarction (STEMI) associated with proximal left…
View article: Deubiquitination of RIPK3 by OTUB2 potentiates neuronal necroptosis after ischemic stroke
Deubiquitination of RIPK3 by OTUB2 potentiates neuronal necroptosis after ischemic stroke Open
As a common and severe cerebrovascular disease, ischemic stroke casts a significant shadow over global health. Unfortunately, the mechanisms regulating neuronal death in the affected areas remain largely unclear. Here, we found that deleti…
View article: SERINC4 is dispensable for male fertility and spermatogenesis in mice
SERINC4 is dispensable for male fertility and spermatogenesis in mice Open
Under physiologic conditions, Serinc4 appears to be dispensable for normal spermatogenesis and male fertility in mice. Future studies are needed to investigate its role under pathologic or aging-related conditions.
View article: Use of Modified YOLOv5 Algorithm in the Differential Diagnosis of Colonic Crohn’s Disease and Ulcerative Colitis on CTE Images
Use of Modified YOLOv5 Algorithm in the Differential Diagnosis of Colonic Crohn’s Disease and Ulcerative Colitis on CTE Images Open
Background: Inflammatory bowel disease (IBD) is an immune‐mediated disorder characterized by intestinal inflammation and includes two subtypes: Crohn’s disease (CD) and ulcerative colitis (UC). The computed tomography manifestations of col…
View article: DCUN1D2 is insignificant for spermatogenesis and male fertility in mice
DCUN1D2 is insignificant for spermatogenesis and male fertility in mice Open
This study indicated that DCUN1D2 has no significant effect on mouse spermatogenesis or male fertility. These findings will help avoid redundant studies and provide new information for the study of human fertility genes.
View article: Research on the supply and demand of elderly care service resources in China
Research on the supply and demand of elderly care service resources in China Open
Purpose This study aims to assess the current status and spatial distribution differences of elderly care service resources supply and demand in China. Methods Semi‐structured qualitative interviews were utilized to gather participants’ in…
View article: Exploring Mechanical Forces Shaping Self-Organization and Morphogenesis During Early Embryo Development
Exploring Mechanical Forces Shaping Self-Organization and Morphogenesis During Early Embryo Development Open
Embryonic development is a dynamic process orchestrated by a delicate interplay of biochemical and biophysical factors. While the role of genetics and biochemistry in embryogenesis has been extensively studied, recent research has highligh…
View article: Dynamics of currents in the Qiongzhou strait during spring and summer based on a numerical simulation
Dynamics of currents in the Qiongzhou strait during spring and summer based on a numerical simulation Open
A high-precision three-dimensional hydrodynamic model based on the Semi-implicit Cross-scale Hydroscience Integrated System Model (SCHISM) was constructed to investigate the characteristics of residual currents in the Qiongzhou Strait duri…
View article: Unveiling the Intricate Connection: Cell Volume as a Key Regulator of Mechanotransduction
Unveiling the Intricate Connection: Cell Volume as a Key Regulator of Mechanotransduction Open
The volumes of living cells undergo dynamic changes to maintain the cells’ structural and functional integrity in many physiological processes. Minor fluctuations in cell volume can serve as intrinsic signals that play a crucial role in ce…
View article: Construction Method and Process Optimization of Prestress Reverse Tensioning for Large‐Span Bidirectional Suspension Steel Roof Structures
Construction Method and Process Optimization of Prestress Reverse Tensioning for Large‐Span Bidirectional Suspension Steel Roof Structures Open
For medium and small‐scale steel structure stadiums, in order to minimize the impact of the construction process on the structural state, a prestressing construction process tailored to medium and small stadiums is proposed, taking full ad…
View article: [Clinical and genetic characteristics of young patients with myeloproliferative neoplasms].
[Clinical and genetic characteristics of young patients with myeloproliferative neoplasms]. Open
Objectives: To investigate the clinical and genetic features of young Chinese patients with myeloproliferative neoplasms (MPN). Methods: In this cross-sectional study, anonymous questionnaires were distributed to patients with MPN patients…
View article: Tocilizumab treatment leads to early resolution of lymphopenia and myeloid dysregulation in patients hospitalized with COVID-19
Tocilizumab treatment leads to early resolution of lymphopenia and myeloid dysregulation in patients hospitalized with COVID-19 Open
High interleukin (IL)-6 levels are associated with more severe clinical manifestations in patients hospitalized with COVID-19, but the complex role of IL-6 in antiviral and inflammatory processes has made it difficult to decipher its invol…
View article: Mating Behavior and Identification of Male-Produced Pheromone Components in Two Woodwasps, Sirex noctilio and Sirex nitobei, in China
Mating Behavior and Identification of Male-Produced Pheromone Components in Two Woodwasps, Sirex noctilio and Sirex nitobei, in China Open
To protect vulnerable trees from native and invasive wood wasps, the mating behavior of these two woodwasp species (S. noctilio and S. nitobei, respectively) and factors influencing this behavior were investigated in cages outdoors. Male-p…
View article: The Effect of Geometry and TGF‐<i>β</i> Signaling on Tumor Cell Migration from Free‐Standing Microtissues
The Effect of Geometry and TGF‐<i>β</i> Signaling on Tumor Cell Migration from Free‐Standing Microtissues Open
Recapitulation of 3D multicellular tissues in vitro is of great interest to the field of tumor biology to study the integrated effect of local biochemical and biophysical signals on tumor cell migration and invasion. However, most microeng…
View article: The molecular gas resolved by ALMA in the low-metallicity dwarf merging galaxy Haro 11
The molecular gas resolved by ALMA in the low-metallicity dwarf merging galaxy Haro 11 Open
The physical mechanisms for starburst or quenching in less massive ($M_* < 10^{10} M_{\odot}$) galaxies are unclear. The merger is one of the inescapable processes referred to as both starburst and quenching in massive galaxies. However, t…
View article: Different Formation Scenarios of Counter-rotating Stellar Disks in Nearby Galaxies
Different Formation Scenarios of Counter-rotating Stellar Disks in Nearby Galaxies Open
Using the integral field unit (IFU) data from Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey, we select a sample of 101 galaxies with counter-rotating stellar disks and regularly-rotating ionized gas disk. We classify t…