Mingming Tang
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View article: Exploring the mechanisms of protective effect of high-energy X-ray FLASH radiotherapy on intestine through multi omics analysis
Exploring the mechanisms of protective effect of high-energy X-ray FLASH radiotherapy on intestine through multi omics analysis Open
Background The aim of this study is to investigate the potential mechanisms underlying the protective effects of high-energy X-ray FLASH radiotherapy (FLASH-RT) on intestine through multi-omics analysis. Methods This study utilized syngene…
View article: Exploring the role of intestinal microbiota in mitigating acute radiation-induced intestinal injury through high-energy X-ray FLASH radiotherapy via metagenomic analysis
Exploring the role of intestinal microbiota in mitigating acute radiation-induced intestinal injury through high-energy X-ray FLASH radiotherapy via metagenomic analysis Open
Objectives This study preliminarily examines the potential correlation between the gut microbiome and the protective effects of FLASH radiotherapy (FLASH-RT) on intestinal tissue using metagenomic analysis. Methods Compact single high-ener…
View article: PLCXD2 expression relates to the immune microenvironment and prognosis of head and neck squamous cell carcinoma: a retrospective cohort study
PLCXD2 expression relates to the immune microenvironment and prognosis of head and neck squamous cell carcinoma: a retrospective cohort study Open
Our findings demonstrate that elevated PLCXD2 expression in HNSC is significantly associated with advanced tumor stage and poorer patient prognosis. The correlation of PLCXD2 with key tumor-infiltrating immune cells and the CTLA-4 checkpoi…
View article: Analysis and Optimization of Wellbore Structure Considering Casing Stress in Oil and Gas Wells Within Coal Mine Goaf Areas Subject to Overburden Movement
Analysis and Optimization of Wellbore Structure Considering Casing Stress in Oil and Gas Wells Within Coal Mine Goaf Areas Subject to Overburden Movement Open
To address wellbore integrity issues (especially casing strength concerns) of oil and gas wells threatened by overburden movement in coal mine goafs, this study takes a gas well in the goaf of Yanchang Gas Field as the research object. Usi…
View article: Three-Dimensional Modeling of Tidal Delta Reservoirs Based on Sedimentary Dynamics Simulations
Three-Dimensional Modeling of Tidal Delta Reservoirs Based on Sedimentary Dynamics Simulations Open
To increase the reliability of three-dimensional (3D) geological models in areas characterized by sparse well data and poor seismic quality, a sedimentary dynamics simulation was conducted on the J7 tidal delta sedimentary reservoir in the…
View article: The Effectiveness of Nurse-Led Multidimensional Digital Cardiac Rehabilitation in Patients With Unstable Angina Undergoing Percutaneous Coronary Intervention: Emulated Target Trial
The Effectiveness of Nurse-Led Multidimensional Digital Cardiac Rehabilitation in Patients With Unstable Angina Undergoing Percutaneous Coronary Intervention: Emulated Target Trial Open
Background Cardiac rehabilitation (CR) interventions for patients with coronary heart disease are increasingly adopted. However, research on the integration of digital health technologies into CR for patients with unstable angina (UA) unde…
View article: Multi-Index Assessment of Heavy Metal Contamination and Ecological Risks in Paddy Soils Along National Highways in Southern Henan Province, China
Multi-Index Assessment of Heavy Metal Contamination and Ecological Risks in Paddy Soils Along National Highways in Southern Henan Province, China Open
(1) Background: Road traffic emissions significantly influence heavy metal accumulation in roadside agricultural soils, posing risks to food safety. (2) Methods: This study investigated the concentrations of heavy metals (As, Cd, Cu, Cr, H…
View article: OsVPS16 Deficiency Enhances Salinity Tolerance in Rice by Regulating Ion Homeostasis, Antioxidant Activity, and Stress-Responsive Gene Expression
OsVPS16 Deficiency Enhances Salinity Tolerance in Rice by Regulating Ion Homeostasis, Antioxidant Activity, and Stress-Responsive Gene Expression Open
Soil salinization has emerged as a significant global threat to agricultural productivity. Rice is susceptible to salinity stress at the seedling stage. However, the mechanisms underlying rice responses to salinity stress remain incomplete…
View article: Human Midbrain Organoids Enriched With Dopaminergic Neurons for Long‐Term Functional Evaluation
Human Midbrain Organoids Enriched With Dopaminergic Neurons for Long‐Term Functional Evaluation Open
Human midbrain organoids with functional dopaminergic (DA) neurons are invaluable for the therapeutic development of Parkinson's disease (PD). However, current methods face significant limitations, including challenges in generating pint‐s…
View article: <sup>177</sup>Lu-Labeled Anticlaudin 6 Monoclonal Antibody for Targeted Therapy in Esophageal Cancer
<sup>177</sup>Lu-Labeled Anticlaudin 6 Monoclonal Antibody for Targeted Therapy in Esophageal Cancer Open
Advanced or metastatic esophageal cancer (EC) is associated with poor prognosis, necessitating new and effective treatment methods. We assess whether claudin 6 (CLDN6) is a useful target for the imaging and radiopharmaceutical therapy of E…
View article: Interpretable machine learning models for predicting skip metastasis in cN0 papillary thyroid cancer based on clinicopathological and elastography radiomics features
Interpretable machine learning models for predicting skip metastasis in cN0 papillary thyroid cancer based on clinicopathological and elastography radiomics features Open
Background Skip lymph node metastasis (SLNM) in papillary thyroid cancer (PTC) involves cancer cells bypassing central nodes to directly metastasize to lateral nodes, often undetected by standard preoperative ultrasonography. Although mult…
View article: Manufacturing natural soap-base (Multiclean) with the addition of wuluh starfruit extraction (Averrhoa)
Manufacturing natural soap-base (Multiclean) with the addition of wuluh starfruit extraction (Averrhoa) Open
Starfruit extract is used as a base for making natural soap that is more environmentally friendly and beneficial for health. The aim of this study is to identify the optimal conditions for adding starfruit extract to natural soap productio…
View article: FLASH radiotherapy using high-energy X-rays: validation of the FLASH effect triggered by a compact single high-energy X-ray source device
FLASH radiotherapy using high-energy X-rays: validation of the FLASH effect triggered by a compact single high-energy X-ray source device Open
Purpose: This preclinical study aimed to verify the FLASH effect of compact single high-energy X-ray source (CHEXs) and to explore whether three irradiations with single-gantry rotation two 30 s pauses can generate FLASH effect in mice. Ma…
View article: A Novel Method for Analyzing Sandbar Distribution in Shelf-Type Tidal Deltas Using Sediment Dynamic Simulation
A Novel Method for Analyzing Sandbar Distribution in Shelf-Type Tidal Deltas Using Sediment Dynamic Simulation Open
Shallow marine shelf sedimentation is a hot and difficult topic in today’s reservoir sedimentology research, and it is widely present in the world. The shallow marine shelf sedimentation is not only affected by complex hydrodynamic effects…
View article: SPP1 promotes tumor progression in esophageal carcinoma by activating focal adhesion pathway
SPP1 promotes tumor progression in esophageal carcinoma by activating focal adhesion pathway Open
SPP1 promotes tumor progression in ESCA by activating FAK/Erk pathway, and FAK is a potential therapeutic target to overcome tumor recurrence and metastasis of ESCA.
View article: PLCXD2 expression relates to the immune microenvironment and prognosis of head and neck squamous cell carcinoma
PLCXD2 expression relates to the immune microenvironment and prognosis of head and neck squamous cell carcinoma Open
Objective — Despite the advances in oncology, the prognosis of head and neck squamous cell carcinoma (HNSC) patients remains dismal. In this study, we aimed to determine the relevance of PLCXD2 expression in the tumor microenvironment to t…
View article: Actin filament‐associated protein 1‐antisense RNA1 promotes the development and invasion of tongue squamous cell carcinoma via the AFAP1‐AS1/miR‐133a‐5p/ZIC2 axis
Actin filament‐associated protein 1‐antisense RNA1 promotes the development and invasion of tongue squamous cell carcinoma via the AFAP1‐AS1/miR‐133a‐5p/ZIC2 axis Open
Background The present study aimed to explore the biological role and underlying mechanism of the long non‐coding RNA actin filament‐associated protein 1‐antisense RNA1 (lncRNA AFAP1‐AS1) in the progression of tongue squamous cell carcinom…
View article: A Seismic Inversion Method Based on Multi-Scale Super-Asymmetric Cycle-JNet Network
A Seismic Inversion Method Based on Multi-Scale Super-Asymmetric Cycle-JNet Network Open
In order to improve the resolution and accuracy of seismic inversion, this study constructs a multi-scale super-asymmetric network (Cycle-JNet). In this model, wavelet analysis is used to capture the multi-scale data characteristics of wel…
View article: Sequence Stratigraphy of the Jurassic Strata and Occurrences of Potential Sandstone Reservoirs in the ST Gas Field, Northern West Siberia Basin
Sequence Stratigraphy of the Jurassic Strata and Occurrences of Potential Sandstone Reservoirs in the ST Gas Field, Northern West Siberia Basin Open
Jurassic strata in the ST gas field of the northern West Siberia Basin have been regarded as a potential exploration target with undiscovered hydrocarbon resources. However limited research has been performed on the sequence stratigraphy o…
View article: Dampak Pembuangan Sampah di Pesisir Pantai Terhadap Lingkungan
Dampak Pembuangan Sampah di Pesisir Pantai Terhadap Lingkungan Open
Garbage is something that is produced from human activities and then is not used and then thrown away. Coastal waste has become a global problem and is an issue that is being widely discussed. This is because coastal waste has an impact on…
View article: Research on Multivariable Fuzzy Dynamic Matrix Control Algorithm
Research on Multivariable Fuzzy Dynamic Matrix Control Algorithm Open
To improve the control quality of distillation tower systems that suffer from issues such as coupling, delay, and nonlinearity, traditional control methods have been ineffective. Consequently, this paper proposes using a variable-domain fu…
View article: A novel frequency-dependent lattice Boltzmann model with a single force term for electromagnetic wave propagation in dispersive media
A novel frequency-dependent lattice Boltzmann model with a single force term for electromagnetic wave propagation in dispersive media Open
Electromagnetic wave simulation is of pivotal importance in the design and implementation of photonic nano-structures. In this study, we developed a lattice Boltzmann model with a single extended force term (LBM-SEF) to simulate the propag…
View article: PCK2 inhibits lung adenocarcinoma tumor cell immune escape through oxidative stress-induced senescence as a potential therapeutic target
PCK2 inhibits lung adenocarcinoma tumor cell immune escape through oxidative stress-induced senescence as a potential therapeutic target Open
An increased expression of PCK2 may be employed as a novel prognostic biomarker in patients with lung adenocarcinoma and has been shown to increase OS, DSS, and PFI. Improving the prognosis of lung adenocarcinoma by interference with PCK2 …