Explanipedia

Phenothiazine-Based Fluorescence-Quenched Photoacoustic Contrast Agents for Molecular Imaging Open

Xin Huang, Yi Wang, Zhiting Wu, Ming-Jie Jia, Qingqing Wang , et al. · 2025

Photoacoustic imaging (PAI), renowned for its high spatial resolution and deep tissue penetration, holds great promise for disease diagnosis and molecular detection. However, the performance of commercially available PAI contrast agent is …

Global burden of thyroid cancer among adolescents and young adults, 1990-2021, and projections to 2050: an analysis based on the GBD 2021 Open

Ming-Jie Jia, Shen Wang, Yu Li, Xianjing Liu, Feng Jiang , et al. · 2025

Objective To evaluate the global burden of thyroid cancer (TC) among adolescents and young adults (AYA) aged 15-39 years from 1990 to 2021, with projections to 2050, and identify demographic and regional disparities. Methods Using Global B…

Effect of trace elements and nutrients on 21 autoimmune diseases: a Mendelian randomization study Open

Ming-Jie Jia, Hua-Fang Yin, Ying-Chao Liang, Feng Jiang, Hui-Lin Li · 2025

Background Numerous clinical studies have observed a close relationship between serum trace elements, nutrients, and autoimmune diseases. However, whether there is a genetic causal effect between serum trace elements, nutrients, and autoim…

Associations between Systemic Immune-Inflammation Index Trajectories and 28-Day Survival Rate in Patients with Copd Patients Admitted to Icu: Insights from Longitudinal Group Trajectory Modeling Open

Hua-Fang Yin, Shanwei Zhu, Shen Wang, Ming-Jie Jia, Feng Jiang , et al. · 2025

Genetically predicted serum metabolites mediate the association between inflammatory proteins and polycystic ovary syndrome: a Mendelian randomization study Open

Ming-Jie Jia, Li Zhou, Xianjing Liu, Hui-Lin Li · 2024

Objective To investigate the association between polycystic ovary syndrome (PCOS) and inflammatory proteins, and to identify and quantify the role of serum metabolites as potential mediators. Methods Utilizing summary-level data from a gen…

The effect of green tea on patients with type 2 diabetes mellitus: A meta-analysis Open

Ming-Jie Jia, Xianjing Liu, Ying-Chao Liang, Deliang Liu, Hui-Lin Li · 2024

Background: To systematically evaluate the effect of green tea on patients with type 2 diabetes. Methods: A computer search Cochrane, PubMed, Embase, CNKI, Wanfang, VIP, and other Chinese and English databases were conducted for randomized…

Effect of trace elements and nutrients on diabetes and its complications: a Mendelian randomization study Open

Ming-Jie Jia, Long Chen · 2024

Background Multiple clinical studies have observed a close relationship between serum trace elements and nutrients and diabetes and its complications, but it remains unclear whether there is a genetic causal effect between serum trace elem…

Association between Tea Intake and Alcohol Consumption and Diabetes Complications:A TwoSample Mendelian Randomization Study Open

Ming-Jie Jia, Hui-Lin Li · 2024

Association of circulating inflammatory proteins with Nonalcoholic Fatty Liver Diseas: a bidirectional Mendelian randomization study Open

Ming-Jie Jia, Long Chen, Hui-Lin Li · 2024

Objective: Investigating the causal relationship between non-alcoholic fatty liver disease (NAFLD) and inflammatory proteins and identifying and quantifying the role of serum metabolites as a potential mediator. Methods: Using summary-leve…

Association of circulating inflammatory proteins with type 2 diabetes mellitus and its complications: a bidirectional Mendelian randomization study Open

Ying-Chao Liang, Ming-Jie Jia, Ling Li, Deliang Liu, Shu‐Fang Chu , et al. · 2024

Background Increasing evidence indicates that immune response underlies the pathology of type 2 diabetes (T2D). Nevertheless, the specific inflammatory regulators involved in this pathogenesis remain unclear. Methods We systematically expl…

From small to large—The application of in situ polymerization within tumor cells Open

Ming-Jie Jia, Yonghang Liu, Peng Wei, Tao Yi · 2024

The “laboratory” of cells has the capacity to polymerize monosaccharides, amino acids, and nucleotides. Tumor cells, characterized by the overexpression of multiple enzymes and existing in a slightly acidic and highly redox‐potent environm…

Association between tea intake and alcohol consumption and diabetes complications: A two sample Mendelian randomization study Open

Ming-Jie Jia · 2024

Background: Studies have indicated that there is a relationship between tea drinking, alcohol consumption, and a reduced risk of diabetes and its complications. However, there is currently no consensus on the potential relationships betwee…

Association between coffee consumption and diabetic complications: A two- sample Mendelian randomization study Open

Yingchao Liang, Xinyu Hu, Ming-Jie Jia, Deliang Liu, Shufang Chu , et al. · 2023

In response to the current clinical debate regarding the causal relationship between coffee consumption and the risk of diabetic complications, we conducted a two-sample Mendelian randomization study to determine the impact of coffee on di…

Identification and validation of aging-related gene signatures and their immune landscape in diabetic nephropathy Open

Yingchao Liang, Zhiyi Liang, Jinxian Huang, Ming-Jie Jia, Deliang Liu , et al. · 2023

Background Aging and immune infiltration have essential role in the physiopathological mechanisms of diabetic nephropathy (DN), but their relationship has not been systematically elucidated. We identified aging-related characteristic genes…

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