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View article: The γ-secretase catalytic subunit PSEN1, regulated by YY1, promotes lung adenocarcinoma progression via the Notch1/EGFR pathway
The γ-secretase catalytic subunit PSEN1, regulated by YY1, promotes lung adenocarcinoma progression via the Notch1/EGFR pathway Open
Backgroud: Serving as a pivotal catalytic component of the γ-secretase, PSEN1 is recognized for its significant influence on the initiation and advancement of tumors. Nevertheless, the specific function and the fundamental mechanisms by wh…
View article: <scp>HDAC3</scp> in action: Expanding roles in inflammation and inflammatory diseases
<span>HDAC3</span> in action: Expanding roles in inflammation and inflammatory diseases Open
Inflammation serves as the foundation for numerous physiological and pathological processes, driving the onset and progression of various diseases. Histone deacetylase 3 (HDAC3), an essential chromatin‐modifying protein within the histone …
View article: [Research Progress of the Effect of Mediterranean Diet on the Correlation of Lung Cancer].
[Research Progress of the Effect of Mediterranean Diet on the Correlation of Lung Cancer]. Open
Lung cancer is one of the top 10 causes of death in the world today, and it is a great concern worldwide for its high mortality rate. Currently, the researchers are digging into various factors influencing the occurrence and development of…
View article: Novel insights and new therapeutic potentials for macrophages in pulmonary hypertension
Novel insights and new therapeutic potentials for macrophages in pulmonary hypertension Open
View article: Eriocitrin inhibits epithelial-mesenchymal transformation (EMT) in lung adenocarcinoma cells via triggering ferroptosis
Eriocitrin inhibits epithelial-mesenchymal transformation (EMT) in lung adenocarcinoma cells via triggering ferroptosis Open
Our findings further support the anti-cancer properties of eriocitrin, as evidenced by its ability to inhibit the EMT process in LUAD cells, which is partially mediated through induction of ferroptosis in cancer cells.
View article: Photoluminescence manipulation in two-dimensional transition metal dichalcogenides
Photoluminescence manipulation in two-dimensional transition metal dichalcogenides Open
Two-dimensional transition metal dichalcogenides (TMDCs) have been regarded as an intriguing platform for exploring novel physical phenomena and optoelectronic devices due to their excitonic emission characteristics derived from the atomic…
View article: Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage
Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage Open
Uridine metabolism is extensively reported to be involved in combating oxidative stress. Redox-imbalance-mediated ferroptosis plays a pivotal role in sepsis-induced acute lung injury (ALI). This study aims to explore the role of uridine me…
View article: Puerarin: A protective drug against ischemia-reperfusion injury
Puerarin: A protective drug against ischemia-reperfusion injury Open
Ischemia-reperfusion (I/R) is a pathological process that occurs in numerous organs throughout the human body and is frequently associated with severe cellular damage and death. Puerarin is an isoflavone compound extracted from the root of…