Mingli Sun
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View article: Progress of anti-tuberculosis drug targets and novel therapeutic strategies
Progress of anti-tuberculosis drug targets and novel therapeutic strategies Open
Tuberculosis, a chronic infectious disease caused by Mycobacterium tuberculosis complex, has re-emerged as the leading cause of death worldwide as a single infectious agent. The increasing prevalence of multidrug-resistant tuberculosis and…
View article: Analogous optical coherent state sourced by a partially coherent beam
Analogous optical coherent state sourced by a partially coherent beam Open
View article: The recent advances in vaccine adjuvants
The recent advances in vaccine adjuvants Open
Vaccine adjuvants, as key components in enhancing vaccine immunogenicity, play a vital role in modern vaccinology. This review systematically examines the historical evolution and mechanisms of vaccine adjuvants, with particular emphasis o…
View article: Genetic Analysis and Fingerprint Construction for Isatis indigotica Fort. Using SSR Markers
Genetic Analysis and Fingerprint Construction for Isatis indigotica Fort. Using SSR Markers Open
Isatis indigotica Fort. is a traditional medicinal plant, which has anti-inflammatory, antioxidant, and antiviral properties. Despite the development and licensing of several cultivars in recent years, morphological similarity among cultiv…
View article: Hydrogen Sulfide Promotes TAM‐M1 Polarization through Activating IRE‐1α Pathway via GRP78 S‐Sulfhydrylation to against Breast Cancer
Hydrogen Sulfide Promotes TAM‐M1 Polarization through Activating IRE‐1α Pathway via GRP78 S‐Sulfhydrylation to against Breast Cancer Open
Hydrogen sulfide (H 2 S)‐mediated protein S‐sulfhydration has been shown to play critical roles in several diseases. Tumor‐associated macrophages (TAMs) are the predominant population of immune cells present within solid tumor tissues, and…
View article: Enhancing photoredox catalysis by suppressing back electron transfer with the aid of a spin catalyst
Enhancing photoredox catalysis by suppressing back electron transfer with the aid of a spin catalyst Open
We report an exceptional role of Gd complex as a spin catalyst in enhancing photoredox reaction by promoting the singlet-to-triplet spin conversion of radical pair intermediates and suppressing back electron transfer.
View article: Potential role of endoplasmic reticulum stress in doxorubicin-induced cardiotoxicity-an update
Potential role of endoplasmic reticulum stress in doxorubicin-induced cardiotoxicity-an update Open
As a chemotherapy agent, doxorubicin is used to combat cancer. However, cardiotoxicity has limited its use. The existing strategies fail to eliminate doxorubicin-induced cardiotoxicity, and an in-depth exploration of its pathogenesis is in…
View article: Intermittent fasting and health outcomes: an umbrella review of systematic reviews and meta-analyses of randomised controlled trials
Intermittent fasting and health outcomes: an umbrella review of systematic reviews and meta-analyses of randomised controlled trials Open
View article: Moderate mechanical stress suppresses chondrocyte ferroptosis in osteoarthritis by regulating NF-κB p65/GPX4 signaling pathway
Moderate mechanical stress suppresses chondrocyte ferroptosis in osteoarthritis by regulating NF-κB p65/GPX4 signaling pathway Open
Ferroptosis is a recently identified form of programmed cell death that plays an important role in the pathophysiological process of osteoarthritis (OA). Herein, we investigated the protective effect of moderate mechanical stress on chondr…
View article: Manipulation of optical orbit-induced localized spin angular momentum using the periodic edge dislocation
Manipulation of optical orbit-induced localized spin angular momentum using the periodic edge dislocation Open
Orbit-induced localized spin angular momentum (OILS) has recently garnered significant attention. This paper introduces periodic edge dislocation (PED) into the tight focusing system. The study delves into the tight focusing characteristic…
View article: SH3RF2 contributes to cisplatin resistance in ovarian cancer cells by promoting RBPMS degradation
SH3RF2 contributes to cisplatin resistance in ovarian cancer cells by promoting RBPMS degradation Open
View article: Dawn Chorus: Digital Art Installation for Public Healing Based on Auditory-Visual Stimulation
Dawn Chorus: Digital Art Installation for Public Healing Based on Auditory-Visual Stimulation Open
View article: Multi-focused electric and magnetic field sourcing from an azimuthally polarized vortex circular hyperbolic umbilic beam
Multi-focused electric and magnetic field sourcing from an azimuthally polarized vortex circular hyperbolic umbilic beam Open
In this paper, one kind of multi-focusing electric and magnetic field which is sourced from an azimuthally polarized vortex circular hyperbolic umbilic beam (APVCHUB) is presented. After passing through a high NA objective, both the electr…
View article: Regulation and therapy, the role of JAK2/STAT3 signaling pathway in OA: a systematic review
Regulation and therapy, the role of JAK2/STAT3 signaling pathway in OA: a systematic review Open
Osteoarthritis (OA) is a multifactorial chronic disease primarily characterized by the degeneration of articular cartilage. Currently, there is a lack of effective treatments for OA other than surgery. The exploration of the mechanisms of …
View article: RNF7 Induces Skeletal Muscle Cell Apoptosis and Arrests Cell Autophagy via Upregulation of THBS1 and Inactivation of the PI3K/Akt Signaling Pathway in a Rat Sepsis Model
RNF7 Induces Skeletal Muscle Cell Apoptosis and Arrests Cell Autophagy via Upregulation of THBS1 and Inactivation of the PI3K/Akt Signaling Pathway in a Rat Sepsis Model Open
Recently, long noncoding RNAs (lncRNAs) have been highlighted for extensive functionality in sepsis. In this study, we aimed to explore the role of RNF7 in the progression of sepsis.
View article: A Low-Cost Facile Synthesis of Solution Processable N-Phenylcarbazole/Triazine Hybrid Host for Green Tadf Oleds
A Low-Cost Facile Synthesis of Solution Processable N-Phenylcarbazole/Triazine Hybrid Host for Green Tadf Oleds Open
View article: Autofocusing field constructed by ring-arrayed Pearcey Gaussian chirp beams
Autofocusing field constructed by ring-arrayed Pearcey Gaussian chirp beams Open
In this work, we propose and demonstrate the ring-arrayed Pearcey Gaussian chirp beams (RAPGCBs) synthesized by multiple two-dimensional Pearcey beams. The general analytical formula for the propagation of RAPGCBs is presented. We find tha…
View article: The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia
The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia Open
View article: Multi-focus autofocusing circular hyperbolic umbilic beams
Multi-focus autofocusing circular hyperbolic umbilic beams Open
We propose and demonstrate a type of multi-focus autofocusing beams, circular hyperbolic umbilic beams (CHUBs), based on the double-active variable caustics in catastrophe theory. The mathematical form is more general compared to circular …
View article: Association between dietary acid load and cancer risk and prognosis: An updated systematic review and meta-analysis of observational studies
Association between dietary acid load and cancer risk and prognosis: An updated systematic review and meta-analysis of observational studies Open
Epidemiological studies have suggested that dietary acid load (DAL) might be related to the risk and prognosis of cancer, whereas the evidence is contentious. Several high-quality observational studies have been published following a prior…
View article: Protective Effect of Resveratrol on Knee Osteoarthritis and its Molecular Mechanisms: A Recent Review in Preclinical and Clinical Trials
Protective Effect of Resveratrol on Knee Osteoarthritis and its Molecular Mechanisms: A Recent Review in Preclinical and Clinical Trials Open
Osteoarthritis (OA) is one of the progressing chronic joint associated with by many complex factors such as age, obesity, and trauma. Knee osteoarthritis (KOA) is the most common type of OA. KOA is characterized by articular cartilage dest…
View article: Mapping the Hot Spots and Evolution Main Path of Whole-Body Vibration Training Since the 21st Century: A Bibliometric Analysis
Mapping the Hot Spots and Evolution Main Path of Whole-Body Vibration Training Since the 21st Century: A Bibliometric Analysis Open
To evaluate the global scientific output of the research on whole-body vibration training (WBVT) and explore the current status and trends in this field over the past decades using bibliometric methods, we retrieved the literature related …
View article: Effects of low-intensity pulsed ultrasound on knee osteoarthritis: A systematic review and meta-analysis of randomized controlled trials
Effects of low-intensity pulsed ultrasound on knee osteoarthritis: A systematic review and meta-analysis of randomized controlled trials Open
Objective To systemically review the effects of low-intensity pulsed ultrasound (LIPUS) on pain relief and functional recovery in patients with knee osteoarthritis (KOA). Data sources PubMed, Web of Science, Cochrane Library, Physiotherapy…
View article: The Role of Human Epididymis Protein 4 in the Diagnosis and Prognosis of Diseases: An Umbrella Review of Systematic Reviews and Meta-Analyses of Observational Studies
The Role of Human Epididymis Protein 4 in the Diagnosis and Prognosis of Diseases: An Umbrella Review of Systematic Reviews and Meta-Analyses of Observational Studies Open
Background The application of human epididymis protein 4 (HE4) in diverse health diseases, especially in cancers, has been extensively studied in recent decades. To summarize the existing evidence of the aforementioned topic, we conducted …
View article: Phytochemicals with protective effects against acute pancreatitis: a review of recent literature
Phytochemicals with protective effects against acute pancreatitis: a review of recent literature Open
The phytochemicals with anti-inflammatory and antioxidant abilities may be efficient candidate drugs for AP treatment. Importantly, more preclinical investigations are needed to illustrate the efficacy of future phytochemicals.
View article: Correction: Intrinsic adriamycin resistance in p53-mutated breast cancer is related to the miR-30c/FANCF/REV1-mediated DNA damage response
Correction: Intrinsic adriamycin resistance in p53-mutated breast cancer is related to the miR-30c/FANCF/REV1-mediated DNA damage response Open
View article: Phytochemicals Mediate Autophagy Against Osteoarthritis by Maintaining Cartilage Homeostasis
Phytochemicals Mediate Autophagy Against Osteoarthritis by Maintaining Cartilage Homeostasis Open
Osteoarthritis (OA) is a common degenerative joint disease and is a leading cause of disability and reduced quality of life worldwide. There are currently no clinical treatments that can stop or slow down OA. Drugs have pain-relieving effe…
View article: Crosstalk Among circRNA/lncRNA, miRNA, and mRNA in Osteoarthritis
Crosstalk Among circRNA/lncRNA, miRNA, and mRNA in Osteoarthritis Open
Osteoarthritis (OA) is a joint disease that is pervasive in life, and the incidence and mortality of OA are increasing, causing many adverse effects on people’s life. Therefore, it is very vital to identify new biomarkers and therapeutic t…
View article: Vortex phase-induced properties of a partially coherent radially polarized circular Airy beam
Vortex phase-induced properties of a partially coherent radially polarized circular Airy beam Open
In this paper, partially coherent radially polarized vortex circular Airy beams (PCRPVCABs) are theoretically and experimentally studied for the first time. Comparing with partially coherent radially polarized circular Airy beam, the autof…
View article: Correction to: HLA-A2.1-restricted ECM1-derived epitope LA through DC cross-activation priming CD8+ T and NK cells: a novel therapeutic tumour vaccine
Correction to: HLA-A2.1-restricted ECM1-derived epitope LA through DC cross-activation priming CD8+ T and NK cells: a novel therapeutic tumour vaccine Open