Mingming Gao
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View article: Bio-Inspired Photocatalytic Nitrogen Fixation: From Nitrogenase Mimicry to Advanced Artificial Systems
Bio-Inspired Photocatalytic Nitrogen Fixation: From Nitrogenase Mimicry to Advanced Artificial Systems Open
Photocatalytic nitrogen fixation under ambient conditions offers a sustainable alternative to the energy-intensive Haber–Bosch process, yet remains limited by the inertness of N≡N bonds and sluggish multi-electron/proton transfer kinetics.…
View article: The correlation of Angiopoietin-like protein 7 and ferroptosis-related proteins in patients with metabolic associated fatty liver disease
The correlation of Angiopoietin-like protein 7 and ferroptosis-related proteins in patients with metabolic associated fatty liver disease Open
Objective The prevalence of metabolic associated fatty liver disease (MAFLD) was increased globally, and data has indicated that ferroptosis participates in the pathogenesis of MAFLD. Angiopoietin-like protein 7 (Angptl 7) is a novel secre…
View article: The macrophage sterol transport protein ORP2 promotes cholesterol efflux and prevents foam cell formation and atherosclerosis
The macrophage sterol transport protein ORP2 promotes cholesterol efflux and prevents foam cell formation and atherosclerosis Open
Cholesterol-loaded macrophage foam cells are a key feature of atherosclerotic plaques. Oxysterol-binding protein-related protein 2 (ORP2) facilitates the transport of cholesterol from lysosomes to the plasma membrane in cultured cell lines…
View article: GPAT4 sustains endoplasmic reticulum homeostasis in endocardial cells and safeguards heart development
GPAT4 sustains endoplasmic reticulum homeostasis in endocardial cells and safeguards heart development Open
View article: Adipose tissue deficiency impairs transient lipid accumulation and delays liver regeneration following partial hepatectomy in male Seipin knockout mice
Adipose tissue deficiency impairs transient lipid accumulation and delays liver regeneration following partial hepatectomy in male Seipin knockout mice Open
Background Liver diseases pose significant health challenges, underscoring the importance of understanding liver regeneration mechanisms. Systemic adipose tissue is thought to be a primary source of lipids and energy during this process; h…
View article: Low-loss, High-rejection UWB Filter with Dual Sharp Notch Characteristics for Wireless Communications
Low-loss, High-rejection UWB Filter with Dual Sharp Notch Characteristics for Wireless Communications Open
View article: Efficacy of neuroendoscopy-assisted surgery in the treatment of chronic subdural hematoma: a meta-analysis
Efficacy of neuroendoscopy-assisted surgery in the treatment of chronic subdural hematoma: a meta-analysis Open
Background Chronic subdural hematoma (CSDH) is one of the most common diseases in neurosurgery. It is the result of chronic intracranial hemorrhage that converges between the dura mater and arachnoid three weeks after externally injuring t…
View article: PI(4)P recruits CIDE proteins to promote the formation of unilocular lipid droplets during adipogenesis and hepatic steatosis
PI(4)P recruits CIDE proteins to promote the formation of unilocular lipid droplets during adipogenesis and hepatic steatosis Open
Lipid droplets (LDs) are evolutionarily conserved organelles that play important roles in metabolism. Each LD is enclosed by a monolayer of phospholipids, distinct from bilayer membranes. The composition of LD surface phospholipids and the…
View article: A miniaturized ultra-wideband filter with high rejection and selectivity based on dual-notch bands
A miniaturized ultra-wideband filter with high rejection and selectivity based on dual-notch bands Open
A novel compact and highly selective Ultra Wide Band (UWB) filter is proposed using multimode resonator (MMR) technology. To begin with, the filter’s ultra-wideband performance is achieved by coupling a stepped-triangular multimode resonat…
View article: A Tight-Connection g-C3N4/BiOBr (001) S-Scheme Heterojunction Photocatalyst for Boosting Photocatalytic Degradation of Organic Pollutants
A Tight-Connection g-C3N4/BiOBr (001) S-Scheme Heterojunction Photocatalyst for Boosting Photocatalytic Degradation of Organic Pollutants Open
The efficient separation of photogenerated charge carriers and strong oxidizing properties can improve photocatalytic performance. Here, we combine the construction of a tightly connected S-scheme heterojunction with the exposure of an act…
View article: A Broadband SIW Cavity-backed Circular Arc-shaped Slot Antenna for Millimeter-wave Applications
A Broadband SIW Cavity-backed Circular Arc-shaped Slot Antenna for Millimeter-wave Applications Open
A broadband circular arc-shaped slot antenna is proposed in this paper which operates from 25.1 GHz to 31.5 GHz.The antenna is based on a substrate-integrated waveguide (SIW) and fed through a grounded coplanar waveguide (GCPW).A circular …
View article: Controllable Multimode Four-Passband Filter Based on Substrate-integrated Waveguide
Controllable Multimode Four-Passband Filter Based on Substrate-integrated Waveguide Open
View article: Intermittent fasting boosts antitumor immunity by restricting CD11b <sup>+</sup>Ly6C <sup>low</sup> Ly6G <sup>low</sup> cell viability through glucose metabolism in murine breast tumor model
Intermittent fasting boosts antitumor immunity by restricting CD11b <sup>+</sup>Ly6C <sup>low</sup> Ly6G <sup>low</sup> cell viability through glucose metabolism in murine breast tumor model Open
Intermittent fasting can benefit breast cancer patients undergoing chemotherapy or immunotherapy. However, it is still uncertain how to select immunotherapy drugs to combine with intermittent fasting. Herein we observed that two cycles of …
View article: Hepatocyte FoxO1 Deficiency Protects From Liver Fibrosis via Reducing Inflammation and TGF-β1-mediated HSC Activation
Hepatocyte FoxO1 Deficiency Protects From Liver Fibrosis via Reducing Inflammation and TGF-β1-mediated HSC Activation Open
View article: GPAT3 regulates the synthesis of lipid intermediate LPA and exacerbates Kupffer cell inflammation mediated by the ERK signaling pathway
GPAT3 regulates the synthesis of lipid intermediate LPA and exacerbates Kupffer cell inflammation mediated by the ERK signaling pathway Open
In the process of inflammatory activation, macrophages exhibit lipid metabolism disorders and accumulate lipid droplets. Kupffer cells (KCs) are the resident hepatic macrophage with critical defense functions in the pathogenesis of several…
View article: Design of double-notch UWB filter with upper stopband characteristics based on ACPW-DGS
Design of double-notch UWB filter with upper stopband characteristics based on ACPW-DGS Open
In this manuscript, a compact (size only 9.8mm*9.8mm) Ultra Wide Band (UWB) bandpass filter with a new structure is proposed, which can be used in the UWB wireless communication band authorized by the FCC. The top plane is composed of a pa…
View article: Sixteen-element Broadband Circularly Polarized Microstrip Antenna Array for S-band
Sixteen-element Broadband Circularly Polarized Microstrip Antenna Array for S-band Open
In this paper, a broadband circularly polarized (CP) microstrip antenna array for S-band is proposed.The antenna consists of a parallel rotating feed network, sixteen units with cut corners, adding rectangular perturbations, and the guided…
View article: Quaternion MIMO Millimeter Wave Antenna for 5G Applications
Quaternion MIMO Millimeter Wave Antenna for 5G Applications Open
In order to reduce the multipath fading caused by the reflection of various obstacles in shortdistance communication, this paper designs a quaternion MIMO millimeter wave antenna working at 28 GHz.The antenna design adopts an inverted trap…
View article: A Broadband Power Amplifier Based on a Novel Filter Matching Network
A Broadband Power Amplifier Based on a Novel Filter Matching Network Open
This paper presents a new realization method of a broadband power amplifier based on a novel filter matching network. The novel matching network based on band-pass filter has an excellent frequency-selection function, which can ensure the …
View article: Integrated lipidomics and network pharmacology analysis to reveal the mechanisms of berberine in the treatment of hyperlipidemia
Integrated lipidomics and network pharmacology analysis to reveal the mechanisms of berberine in the treatment of hyperlipidemia Open
View article: CRISPR/Cas9 based blockade of IL-10 signaling impairs lipid and tissue homeostasis to accelerate atherosclerosis
CRISPR/Cas9 based blockade of IL-10 signaling impairs lipid and tissue homeostasis to accelerate atherosclerosis Open
Interleukin-10 (IL-10) is a widely recognized immunosuppressive factor. Although the concept that IL-10 executes an anti-inflammatory role is accepted, the relationship between IL-10 and atherosclerosis is still unclear, thus limiting the …
View article: A Deep Learning-Based Parameter Prediction Method for Coal Slime Blending Circulating Fluidized Bed Units
A Deep Learning-Based Parameter Prediction Method for Coal Slime Blending Circulating Fluidized Bed Units Open
Coal slime blending can effectively improve the utilization rate of fossil fuels and reduce environmental pollution. However, the combustion in the furnace is unstable due to the empty pump phenomenon during the coal slurry transport. The …
View article: Interactions of Vallisneria natans and Iron-Oxidizing Bacteria Enhance Iron-Bound Phosphorus Formation in Eutrophic Lake Sediments
Interactions of Vallisneria natans and Iron-Oxidizing Bacteria Enhance Iron-Bound Phosphorus Formation in Eutrophic Lake Sediments Open
Submerged macrophyte restoration and in situ phosphorus (P) passivation are effective methods for the control of internal P loading from sediments. This study explored the synergistic effects of Vallisneria natans and iron (Fe)-oxidizing b…
View article: Targeting ApoC3 Paradoxically Aggravates Atherosclerosis in Hamsters With Severe Refractory Hypercholesterolemia
Targeting ApoC3 Paradoxically Aggravates Atherosclerosis in Hamsters With Severe Refractory Hypercholesterolemia Open
Rationale ApoC3 plays a central role in the hydrolysis process of triglyceride (TG)-rich lipoproteins mediated by lipoprotein lipase (LPL), which levels are positively associated with the incidence of cardiovascular disease (CVD). Although…
View article: New Dual-passband SIW Filter with Loaded T-slot
New Dual-passband SIW Filter with Loaded T-slot Open
In order to effectively improve filter selectivity and out-of-band rejection level, a multicavity two-mode dual-passband filter operating in X-band is proposed.By designing a suitable circuit topology, the bandpasss of the filter are forme…
View article: CRISPR/Cas9 Based Blockade of IL-10 Signaling Impairs Lipid and Tissue Homeostasis to Accelerate Atherosclerosis
CRISPR/Cas9 Based Blockade of IL-10 Signaling Impairs Lipid and Tissue Homeostasis to Accelerate Atherosclerosis Open
View article: Idol Depletion Protects against Spontaneous Atherosclerosis in a Hamster Model of Familial Hypercholesterolemia
Idol Depletion Protects against Spontaneous Atherosclerosis in a Hamster Model of Familial Hypercholesterolemia Open
Inducible degrader of low‐density lipoprotein (LDL) receptor (Idol) is an E3 ubiquitin ligase coded by Idol , the target gene of liver X receptor (LXR), which primarily mediates the ubiquitination and lysosomal degradation of low‐density l…
View article: AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway
AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway Open
AGPATs (1-acylglycerol-3-phosphate O -acyltransferases) catalyze the acylation of lysophosphatidic acid to form phosphatidic acid (PA), a key step in the glycerol-3-phosphate pathway for the synthesis of phospholipids and triacylglycerols.…
View article: Deletion of Seipin Attenuates Vascular Function and the Anticontractile Effect of Perivascular Adipose Tissue
Deletion of Seipin Attenuates Vascular Function and the Anticontractile Effect of Perivascular Adipose Tissue Open
Seipin locates in endoplasmic reticulum (ER) and regulates adipogenesis and lipid droplet formation. Deletion of Seipin has been well-demonstrated to cause severe general lipodystrophy, however, its role in maintaining perivascular adipose…
View article: Correction of Familial LCAT Deficiency by AAV-hLCAT Prevents Renal Injury and Atherosclerosis in Hamsters—Brief Report
Correction of Familial LCAT Deficiency by AAV-hLCAT Prevents Renal Injury and Atherosclerosis in Hamsters—Brief Report Open
Objective: Familial lecithin:cholesterol acyltransferase (LCAT) deficiency is a rare human disease characterized by very low HDL (high-density lipoprotein) and elevated free cholesterol, in which renal injury has been confirmed in, but whe…