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View article: A scoping review of hydroxyapatite-modified glass ionomer cements used for restorative dentistry
A scoping review of hydroxyapatite-modified glass ionomer cements used for restorative dentistry Open
This scoping review provides a valuable overview of HA modified-GICs research. Additionally, it identifies potential research areas that can be investigated further to enhance properties of HA modified-GICs for clinical application.
View article: Advanced Laboratory Assessments in Caries Mineralization Research: A Review
Advanced Laboratory Assessments in Caries Mineralization Research: A Review Open
Dental caries is characterized by the dynamic processes of demineralization and remineralization. Recent advancements in cariology research have introduced sophisticated techniques such as nanoindentation, nano-computed tomography, optical…
View article: Silver diamine fluoride treatment for the management of deep caries: A scoping review
Silver diamine fluoride treatment for the management of deep caries: A scoping review Open
This scoping review provides a valuable overview of the range of potential factors that should be considered regarding SDF research on deep caries. Standardised clinical protocols and strategies to minimise staining could further improve i…
View article: Microstructure evolution and improved tribological properties of laser deposited Fe-36Ni alloy coating with B addition
Microstructure evolution and improved tribological properties of laser deposited Fe-36Ni alloy coating with B addition Open
In this study, Invar alloy coatings with varying B content (1–6 wt%) were prepared by laser deposition to investigate the effects of B alloying on the microstructure, hardness, and wear resistance of coatings. The results indicated that th…
View article: Development and characterisation of a novel antimicrobial peptide GA-C16G2 targeting Streptococcus mutans
Development and characterisation of a novel antimicrobial peptide GA-C16G2 targeting Streptococcus mutans Open
GA-C16G2 offers a novel therapeutic approach for targeted prevention and treatment of dental caries.
View article: AI-Driven Dental Caries Management Strategies: From Clinical Practice to Professional Education and Public Self Care
AI-Driven Dental Caries Management Strategies: From Clinical Practice to Professional Education and Public Self Care Open
Dental caries is one of the most prevalent chronic diseases among both children and adults, despite being largely preventable. This condition has significant negative impacts on human health and imposes a substantial economic burden. In re…
View article: Acid‐Resistant Glass Ionomer Cements: An Assessment of Their Mechanical Properties, Fluoride Ion Release and Protection to Surrounding Tooth Surfaces From Acid Challenges
Acid‐Resistant Glass Ionomer Cements: An Assessment of Their Mechanical Properties, Fluoride Ion Release and Protection to Surrounding Tooth Surfaces From Acid Challenges Open
New acid‐resistant glass ionomer cements (GIC) claim to be able to withstand acidic conditions while also protecting surrounding tooth structures and preserving function. Currently, there are only a few studies that assessed mechanical pro…
View article: Observation on efficacy of autologous platelet rich fibrin combined with ultra-pulsed carbon dioxide laser in the treatment of cancellous bone exposed wounds
Observation on efficacy of autologous platelet rich fibrin combined with ultra-pulsed carbon dioxide laser in the treatment of cancellous bone exposed wounds Open
This study is to evaluate the effectiveness of autologous platelet-rich fibrin (PRF) combined with ultra-pulsed carbon dioxide laser in treating cancellous bone-exposed wounds. A total of 65 patients with cancellous bone-exposed wounds wer…
View article: Effect of calcium and phosphate in an artificial chemical model of root caries formation
Effect of calcium and phosphate in an artificial chemical model of root caries formation Open
Artificial root caries lesions were associated with decreased mineral loss in solutions containing higher concentrations of calcium phosphate or in the presence of fluoride, compared with those formed in solutions with lower calcium phosph…
View article: Discovery, biological evaluations, and modified applications of peptide AVHS derived from dental plaque biofilms
Discovery, biological evaluations, and modified applications of peptide AVHS derived from dental plaque biofilms Open
The conjugate AVHS@RWWRWW, derived from a dominant metabolite Ala-Val-His-Ser (AVHS) in caries-free children, exhibits potent antibiofilm activity and significantly reduces caries in rats, showing promise as a preventive agent.
View article: Effect of sodium hypochlorite and EDTA pretreatment on the resin infiltration efficacy and acid resistance of enamel white spot lesions: an in vitro study
Effect of sodium hypochlorite and EDTA pretreatment on the resin infiltration efficacy and acid resistance of enamel white spot lesions: an in vitro study Open
Enamel surface pretreatment of 5.25% NaOCl or combined with 17% EDTA improved the efficacy of the resin infiltration of WSLs, but might be useless in enhancing the acid resistance of resin-infiltrated WSLs.
View article: Tooth-Binding Graphene Quantum Dots Silver Nanocomposites for Prevention of Dental Caries
Tooth-Binding Graphene Quantum Dots Silver Nanocomposites for Prevention of Dental Caries Open
This study developed a biocompatible and tooth-binding ALN-GQDs-Ag with promising antibacterial, mineralising, and non-discolouring properties. ALN-GQDs-Ag could be a novel anti-caries agent for preventing dentine caries if translated for …
View article: In Vitro Models Used in Cariology Mineralisation Research—A Review of the Literature
In Vitro Models Used in Cariology Mineralisation Research—A Review of the Literature Open
Background: Dental caries remains a significant global health problem. One of the fundamental mechanisms underlying the development and progression of dental caries is the dynamic process of demineralisation/remineralisation. In vitro mode…
View article: Dental Applications of Ion-Substituted Hydroxyapatite: A Review of the Literature
Dental Applications of Ion-Substituted Hydroxyapatite: A Review of the Literature Open
Hydroxyapatite (HA) forms an essential constituent of human teeth and bone. Its distinctive characteristic features, such as bioactivity and osteoconductivity, make it an ideal candidate to be used as an implant coating in restorative dent…
View article: A scoping review of the influence of clinical contaminants on bond strength in direct adhesive restorative procedures
A scoping review of the influence of clinical contaminants on bond strength in direct adhesive restorative procedures Open
This scoping review provides a valuable overview of the range of potential clinical contaminants that can influence the bond strength between different interfaces in direct adhesive restorative procedures. Additionally, it identifies poten…
View article: In Vitro Models Used in the Formation of Root Caries Lesions—A Review of the Literature
In Vitro Models Used in the Formation of Root Caries Lesions—A Review of the Literature Open
The management of root caries remains a challenge for clinicians due to its unique anatomical location and structure. There is increasing interest in utilising artificial root caries lesions to develop new strategies for remineralisation. …
View article: Development of a Novel Peptide with Antimicrobial and Mineralising Properties for Caries Management
Development of a Novel Peptide with Antimicrobial and Mineralising Properties for Caries Management Open
The purpose of the study is to develop a novel peptide for caries management. Gallic-Acid-Polyphemusin-I (GAPI) was synthesised by grafting Polyphemusin I (PI) and gallic acid (GA). Biocompatibility was evaluated using a Cell Counting Kit-…
View article: The Anti-Caries Effects of a Novel Peptide on Dentine Caries: An In Vitro Study
The Anti-Caries Effects of a Novel Peptide on Dentine Caries: An In Vitro Study Open
This study aimed to investigate the antibiofilm and remineralising effects of peptide GAPI on artificial dentin caries. After creating artificial carious lesions, eighty dentine blocks were randomly assigned for treatment twice daily with …
View article: Antibacterial Properties of the Antimicrobial Peptide Gallic Acid-Polyphemusin I (GAPI)
Antibacterial Properties of the Antimicrobial Peptide Gallic Acid-Polyphemusin I (GAPI) Open
A novel antimicrobial peptide, GAPI, has been developed recently by grafting gallic acid (GA) to polyphemusin I (PI). The objective of this study was to investigate the antibacterial effects of GAPI on common oral pathogens. This laborator…
View article: The effect of different ferrule heights and crown-to-root ratios on fracture resistance of endodontically-treated mandibular premolars restored with different post-and-core systems: an in vitro study
The effect of different ferrule heights and crown-to-root ratios on fracture resistance of endodontically-treated mandibular premolars restored with different post-and-core systems: an in vitro study Open
Background To investigate the effects of different ferrule heights and crown-to-root ratios on the fracture resistance of endodontically-treated premolars restored with two post-and-core systems. Methods Eighty extracted human mandibular f…
View article: Bioactive Materials for Caries Management: A Literature Review
Bioactive Materials for Caries Management: A Literature Review Open
Researchers have developed novel bioactive materials for caries management. Many clinicians also favour these materials, which fit their contemporary practice philosophy of using the medical model of caries management and minimally invasiv…
View article: Peptide Designs for Use in Caries Management: A Systematic Review
Peptide Designs for Use in Caries Management: A Systematic Review Open
The objective of this study was to review the design methods that have been used to create peptides for use in caries management. Two independent researchers systematically reviewed many in vitro studies in which peptides were designed for…
View article: Potential Beneficial Effects of Hydroxyapatite Nanoparticles on Caries Lesions In Vitro—A Review of the Literature
Potential Beneficial Effects of Hydroxyapatite Nanoparticles on Caries Lesions In Vitro—A Review of the Literature Open
Dental caries is one of the most common human diseases which can occur in both primary and permanent dentitions throughout the life of an individual. Hydroxyapatite is the major inorganic component of human teeth, consequently, nanosized h…
View article: Bioinspired Macrocyclic Molecule Supported Two‐Dimensional Lamellar Membrane with Robust Interlayer Structure for High‐Efficiency Nanofiltration
Bioinspired Macrocyclic Molecule Supported Two‐Dimensional Lamellar Membrane with Robust Interlayer Structure for High‐Efficiency Nanofiltration Open
2D lamellar membranes (2DLMs) are used for efficient desalination and nanofiltration. However, weak interactions between adjacent stacked nanosheets result in susceptibility to swelling that limits practical applicability. Inspired by the …
View article: Exploration and preliminary clinical investigation of an adhesive approach for primary tooth restoration
Exploration and preliminary clinical investigation of an adhesive approach for primary tooth restoration Open
The current study aims to investigate a suitable adhesive for primary tooth enamel. Shear bond strength (SBS) of primary teeth and the length of resin protrusion were analyzed using one-way ANOVA with Bonferroni multiple comparison tests a…
View article: A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel
A comparative study of two chemical models for creating subsurface caries lesions on aprismatic and prismatic enamel Open
Aprismatic enamel and prismatic enamel have similar mineral loss in acetic acid while prismatic enamel showed more mineral loss compared to aprismatic enamel in lactic acid.
View article: Growing Global Research Interest in Antimicrobial Peptides for Caries Management: A Bibliometric Analysis
Growing Global Research Interest in Antimicrobial Peptides for Caries Management: A Bibliometric Analysis Open
Objective: Researchers are studying the use of antimicrobial peptides as functional biomaterials to prevent and treat dental caries. This study aims to investigate the global research interest in antimicrobial peptides for caries managemen…
View article: In Vitro Studies of Graphene for Management of Dental Caries and Periodontal Disease: A Concise Review
In Vitro Studies of Graphene for Management of Dental Caries and Periodontal Disease: A Concise Review Open
Graphene is a single-layer two-dimensional carbon-based nanomaterial. It presents as a thin and strong material that has attracted many researchers’ attention. This study provides a concise review of the potential application of graphene m…