Mingqi Zhang
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View article: Loss of BAP31 Is Detrimentally Aging Photoreceptors Through ER Stress-Mediated Retinal Degeneration
Loss of BAP31 Is Detrimentally Aging Photoreceptors Through ER Stress-Mediated Retinal Degeneration Open
Retinal degeneration (RD) is an intractable ophthalmic disorder with no effective treatments, and its pathogenesis is complex, involving multiple genes. Endoplasmic reticulum (ER) stress and neuronal apoptosis are key factors that drive ne…
View article: Best evidence summary for self-management of radiodermatitis in head and neck cancer patients: an integrative review
Best evidence summary for self-management of radiodermatitis in head and neck cancer patients: an integrative review Open
Aim To evaluate and synthesize the best evidence for radiodermatitis self-management in head and neck cancer (HNC) patients, and to provide evidence-based guidance for improving their self-management capabilities. Design integrative review…
View article: Nanovesicles derived from protocorm-like bodies of Dendrobium officinal enhance corneal epithelial repair and reduce inflammation in dry eye disease models
Nanovesicles derived from protocorm-like bodies of Dendrobium officinal enhance corneal epithelial repair and reduce inflammation in dry eye disease models Open
Plant-derived nanovesicles (PDNVs) offer a promising, biocompatible therapeutic platform. In this study, we isolated nanovesicles from protocorm-like bodies of Dendrobium officinale (PLBs-NVs) and evaluated their efficacy in dry eye diseas…
View article: <i>Chaetomium globosum</i> from <i>Alisma orientale</i> (Sam.) Juzep. enhances the antioxidative stress capacity of <i>Caenorhabditis elegans</i>
<i>Chaetomium globosum</i> from <i>Alisma orientale</i> (Sam.) Juzep. enhances the antioxidative stress capacity of <i>Caenorhabditis elegans</i> Open
Background Medicinal plant endophytic fungi hold significant potential for producing natural antioxidants, as they thrive in environments rich in bioactive antioxidant compounds. Methods This study focuses on Chaetomium globosum , an endop…
View article: Causal relationship between immune cells and venous thromboembolism: a bidirectional two-sample Mendelian randomization study
Causal relationship between immune cells and venous thromboembolism: a bidirectional two-sample Mendelian randomization study Open
This study demonstrates that specific immune cell types are causally linked to VTE, DVT, and PE, providing valuable insights for future clinical research.
View article: Uncertainty in Software Development Projects: A Review of Causes, Types, Challenges, and Future Research Directions
Uncertainty in Software Development Projects: A Review of Causes, Types, Challenges, and Future Research Directions Open
In a rapidly evolving business landscape, the success of software development (SD) projects is increasingly impacted by uncertainty, which poses significant challenges for project managers. Despite the known influence of uncertainty on pro…
View article: Latent Profile Analysis of Pain Catastrophizing in Post-Operative Lung Cancer Patients
Latent Profile Analysis of Pain Catastrophizing in Post-Operative Lung Cancer Patients Open
Three distinct patterns of pain catastrophizing were identified in patients following lung cancer surgery, each exhibiting unique classification characteristics. Healthcare professionals should promptly identify individuals at high risk fo…
View article: Research on Thermal Runaway Failures Mechanism and Flame Dynamics Risk of 32ah Prismatic Lithium-Ion Phosphate Battery Induced by Nail Penetration Under Critical Thermal Load Condition
Research on Thermal Runaway Failures Mechanism and Flame Dynamics Risk of 32ah Prismatic Lithium-Ion Phosphate Battery Induced by Nail Penetration Under Critical Thermal Load Condition Open
View article: Cu-Co Synergistic Enhancement For Low-Temperature Selective No Reduction by Co Over Bimetallic Mof-Derived Catalysts
Cu-Co Synergistic Enhancement For Low-Temperature Selective No Reduction by Co Over Bimetallic Mof-Derived Catalysts Open
View article: Gas Dynamic Characteristics and Fire-Explosion Risk Assessment of the Full Cycle of Thermal Runaway in 70 Ah Prismatic Lithium Iron Phosphate Battery
Gas Dynamic Characteristics and Fire-Explosion Risk Assessment of the Full Cycle of Thermal Runaway in 70 Ah Prismatic Lithium Iron Phosphate Battery Open
View article: Switching indoor fuels and the incidence of physical-psychological-cognitive multimorbidity: A prospective cohort study
Switching indoor fuels and the incidence of physical-psychological-cognitive multimorbidity: A prospective cohort study Open
Long-term solid-fuels use is associated with an increased PPC-multimorbidity incidence, and switching to cleaner fuels is associated with a decreased PPC-multimorbidity incidence in adults aged ≥45 years.
View article: Gastric paraganglioma: a case report and review of literature
Gastric paraganglioma: a case report and review of literature Open
Paragangliomas (PGLs) are rare neuroendocrine tumors which overproduce catecholamines (CAs). They are extra-adrenal, catecholamine-secreting tumors occurring outside the adrenal glands. Gastric PGLs originating from extra-adrenal paragangl…
View article: Gastric and cardiac inflammatory myofibroblastic tumor: an extremely rare case
Gastric and cardiac inflammatory myofibroblastic tumor: an extremely rare case Open
Background Inflammatory myofibroblastic tumor (IMT) is a unique, rarely metastatic tumor composed of myofibroblasts and fibrous spindle cells with inflammatory cell infiltration that can affect any organ in the human body. By reviewing the…
View article: The use of human‐derived feeder layers for the cultivation of transplantable human epidermal cell sheet to repair second degree burn wounds
The use of human‐derived feeder layers for the cultivation of transplantable human epidermal cell sheet to repair second degree burn wounds Open
Background and objectives Human epidermal cell sheet (human‐ECS) is a feasible treatment option for wound injury. Traditionally, researchers often use murine 3T3 fibroblast cells as feeder layer to support human epidermal cell sheet grafts…
View article: Zinc improves neurological recovery by promoting angiogenesis via the astrocyte‐mediated HIF‐1α/VEGF signaling pathway in experimental stroke
Zinc improves neurological recovery by promoting angiogenesis via the astrocyte‐mediated HIF‐1α/VEGF signaling pathway in experimental stroke Open
Background Ischemic stroke is a serious cerebrovascular disease with high morbidity and disability. Zinc accumulation has been shown to play a vital role in neuronal death and blood–brain barrier damage following ischemia in acute stage. H…
View article: Mutational spectrum of syndromic genes in sporadic brain arteriovenous malformation
Mutational spectrum of syndromic genes in sporadic brain arteriovenous malformation Open
Background Brain arteriovenous malformations (BAVMs) are abnormal vessels that are apt to rupture, causing life-threatening intracranial hemorrhage (ICH). The estimated prevalence of BAVMs is 0.05% among otherwise healthy individuals. In t…
View article: Study of the biological characteristics of human umbilical cord mesenchymal stem cells after long-time cryopreservation
Study of the biological characteristics of human umbilical cord mesenchymal stem cells after long-time cryopreservation Open
View article: Nomogram for Stability Stratification of Small Intracranial Aneurysm Based on Clinical and Morphological Risk Factors
Nomogram for Stability Stratification of Small Intracranial Aneurysm Based on Clinical and Morphological Risk Factors Open
Background and Purpose: Stability stratification of intracranial aneurysms (IAs) is crucial for individualized clinical management, especially for small IAs. We aim to develop and validate a nomogram based on clinical and morphological ris…
View article: Genetic Polymorphism Analysis of&nbsp;Mitochondrial DNA from&nbsp;Chinese Guangdong&nbsp;Liannan Yao ethnic group
Genetic Polymorphism Analysis of Mitochondrial DNA from Chinese Guangdong Liannan Yao ethnic group Open
Background Genetic polymorphism and haplotype distribution characteristics analysis of mitochondrial DNA in Chinese Guangdong Liannan Yao group was conducted in this study, to provide genetic basis for tracing the origin and historical mig…
View article: Hemodynamic differences by increasing low profile visualized intraluminal support (LVIS) stent local compaction across intracranial aneurysm orifice
Hemodynamic differences by increasing low profile visualized intraluminal support (LVIS) stent local compaction across intracranial aneurysm orifice Open
Background The Low-profile Visualized Intraluminal Support device (LVIS) has been successfully used to treat cerebral aneurysm, and the push-pull technique has been used clinically to compact the stent across aneurysm orifice. Our aim was …
View article: Intravitreal Injection of Human Retinal Progenitor Cells for Treatment of Retinal Degeneration
Intravitreal Injection of Human Retinal Progenitor Cells for Treatment of Retinal Degeneration Open
BACKGROUND Retinal degeneration causes irreversible blindness. Human retinal progenitor cells (hRPCs) have the potential to treat retinal diseases. The vitreous cavity is a relatively immune-privileged site that is suitable for stem cell t…
View article: Variation of Mass Effect After Using a Flow Diverter With Adjunctive Coil Embolization for Symptomatic Unruptured Large and Giant Intracranial Aneurysms
Variation of Mass Effect After Using a Flow Diverter With Adjunctive Coil Embolization for Symptomatic Unruptured Large and Giant Intracranial Aneurysms Open
Background: Mass effect associated with large or giant aneurysms is an intractable problem for traditional endovascular treatments. Preventing recurrence of aneurysms requires dense coiling, which may aggravate the mass effect. Howe…
View article: Exome sequencing reveals a novel variant in <i>NFX1</i> causing intracranial aneurysm in a Chinese family
Exome sequencing reveals a novel variant in <i>NFX1</i> causing intracranial aneurysm in a Chinese family Open
Background Genetic risk factors play an important role in the pathogenesis of familial intracranial aneurysms (FIAs); however, the molecular mechanisms remain largely unknown. Objective To investigate potential FIA-causing genetic variants…
View article: The Effect of Age on the Regenerative Potential of Human Eyelid Adipose-Derived Stem Cells
The Effect of Age on the Regenerative Potential of Human Eyelid Adipose-Derived Stem Cells Open
Human eyelid adipose-derived stem cells (HEASCs) are a new source of autologous mesenchymal stem cells, which are derived from neuroectoderm and potentially applied in the tissue regeneration and cell therapies. Based on the prevalence of …
View article: Practice of Low-carbon City in China: The Status Quo and Prospect
Practice of Low-carbon City in China: The Status Quo and Prospect Open
It is vital to construct low-carbon city in China in order to mitigate the huge cost of climate change especially when considering the great contribution of cities to the national greenhouse gas emissions. Many Chinese cities have made eff…