Mingrui Xia
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View article: Brain-clinical signatures of basal ganglia-related dysfunctional reorganisation in Parkinson's disease
Brain-clinical signatures of basal ganglia-related dysfunctional reorganisation in Parkinson's disease Open
National Natural Science Foundation of China (Nos. 82071423 and 82021004) and Beijing Natural Science Foundation (No. JQ23033).
View article: Over-integration of visual network in major depressive disorder and its association with gene expression profiles
Over-integration of visual network in major depressive disorder and its association with gene expression profiles Open
Major depressive disorder (MDD) is a common psychiatric condition associated with aberrant functional connectivity in large-scale brain networks. However, it is unclear how the network dysfunction is characterized by imbalance or derangeme…
View article: Toward individual heterogeneity and neurobiological subtypes in attention-deficit/hyperactivity disorder
Toward individual heterogeneity and neurobiological subtypes in attention-deficit/hyperactivity disorder Open
Attention-deficit/hyperactivity disorder (ADHD) is a biologically and clinically heterogeneous neurodevelopmental condition, which hinders the identification of biologically rooted evidence for treatment choices and clinical predictions. I…
View article: White matter functional connectome gradient dysfunction in major depressive disorder
White matter functional connectome gradient dysfunction in major depressive disorder Open
Background Major depressive disorder (MDD) is a prevalent psychiatric disorder with disruptions in brain white matter (WM). While much research has focused on WM structure, the dysfunctional organization of WM in MDD remains poorly underst…
View article: A federated LSTM network for load forecasting using multi-source data with homomorphic encryption
A federated LSTM network for load forecasting using multi-source data with homomorphic encryption Open
Short-term load forecasting is of great significance to the operation of power systems. Various uncertain factors, such as meteorological social data, have already been combined with historical power data to create more accurate load forec…
View article: Disrupted functional connectivity of the emotion regulation network in major depressive disorder and its association with symptom improvement: A multisite resting-state functional MRI study
Disrupted functional connectivity of the emotion regulation network in major depressive disorder and its association with symptom improvement: A multisite resting-state functional MRI study Open
Background The emotion regulation network (ERN) in the brain provides a framework for understanding the neuropathology of affective disorders. Although previous neuroimaging studies have investigated the neurobiological correlates of the E…
View article: Shared differential factors underlying individual spontaneous neural activity abnormalities in major depressive disorder
Shared differential factors underlying individual spontaneous neural activity abnormalities in major depressive disorder Open
Background In contemporary neuroimaging studies, it has been observed that patients with major depressive disorder (MDD) exhibit aberrant spontaneous neural activity, commonly quantified through the amplitude of low-frequency fluctuations …
View article: Functional network modules overlap and are linked to interindividual connectome differences during human brain development
Functional network modules overlap and are linked to interindividual connectome differences during human brain development Open
The modular structure of functional connectomes in the human brain undergoes substantial reorganization during development. However, previous studies have implicitly assumed that each region participates in one single module, ignoring the …
View article: Schizophrenia and Neurodevelopment: Insights From Connectome Perspective
Schizophrenia and Neurodevelopment: Insights From Connectome Perspective Open
Background Schizophrenia is conceptualized as a brain connectome disorder that can emerge as early as late childhood and adolescence. However, the underlying neurodevelopmental basis remains unclear. Recent interest has grown in children a…
View article: Big connectome imaging data in psychiatric disorders
Big connectome imaging data in psychiatric disorders Open
Psychiatric disorders are a pressing public health challenge, posing a significant threat to the well-being of millions of people worldwide. Their elusive etiology, rooted in the complex interplay of genetic, environmental, and neural fact…
View article: Longitudinal associations between language network characteristics in the infant brain and school-age reading abilities are mediated by early-developing phonological skills
Longitudinal associations between language network characteristics in the infant brain and school-age reading abilities are mediated by early-developing phonological skills Open
Reading acquisition is a prolonged learning process relying on language development starting in utero. Behavioral longitudinal studies reveal prospective associations between infant language abilities and preschool/kindergarten phonologica…
View article: Development of the overlapping network modules in the human brain
Development of the overlapping network modules in the human brain Open
Developmental connectomic studies have shown that the modular organization of functional networks in the human brain undergoes substantial reorganization with age to support cognitive growth. However, these studies implicitly assume that e…
View article: Development of segregation and integration of functional connectomes during the first 1,000 days
Development of segregation and integration of functional connectomes during the first 1,000 days Open
The first 1,000 days of human life lay the foundation for brain development and later cognitive growth. However, the developmental rules of the functional connectome during this critical period remain unclear. Using high-resolution, longit…
View article: Normative growth modeling of brain morphology reveals neuroanatomical heterogeneity and biological subtypes in children with ADHD
Normative growth modeling of brain morphology reveals neuroanatomical heterogeneity and biological subtypes in children with ADHD Open
Background Neuroimaging studies suggest substantial individual heterogeneity in brain phenotypes in attention-deficit/hyperactivity disorder (ADHD). However, how these individual-level brain phenotypes contribute to the identification of A…
View article: Topographic, cognitive, and neurobiological profiling of the interdependent structural and functional connectome in the human brain
Topographic, cognitive, and neurobiological profiling of the interdependent structural and functional connectome in the human brain Open
The structural connectome (SC) is tightly coupled to the functional connectome (FC) in the human brain. Most previous related studies have modeled and analyzed SC or FC as isolated brain networks. However, challenges remain in modeling the…
View article: Dysfunction in Sensorimotor and Default Mode Networks: Elucidating the Neural Correlates of Major Depressive Disorder
Dysfunction in Sensorimotor and Default Mode Networks: Elucidating the Neural Correlates of Major Depressive Disorder Open
Major depressive disorder (MDD) is recognized as a severe mental illness with imbalanced interactions among brain networks. However, the detailed mechanisms of large-scale network dysfunction and their clinical implications are not fully u…
View article: Functional connectome through the human life span
Functional connectome through the human life span Open
The lifespan growth of the functional connectome remains unknown. Here, we assemble task-free functional and structural magnetic resonance imaging data from 33,250 individuals aged 32 postmenstrual weeks to 80 years from 132 global sites. …
View article: Development of Sensorimotor-Visual Connectome Gradient at Birth Predicts Cognitive Outcomes at 2 Years of Age
Development of Sensorimotor-Visual Connectome Gradient at Birth Predicts Cognitive Outcomes at 2 Years of Age Open
Functional connectome gradients represent fundamental brain organizing principles. Here, we investigate the maturation of the macroscopic connectome gradients in a task-free functional MRI dataset consisting of 39 preterm and term babies a…
View article: Removal of site effects and enhancement of signal using dual projection independent component analysis for pooling multi‐site MRI data
Removal of site effects and enhancement of signal using dual projection independent component analysis for pooling multi‐site MRI data Open
Combining magnetic resonance imaging (MRI) data from multi‐site studies is a popular approach for constructing larger datasets to greatly enhance the reliability and reproducibility of neuroscience research. However, the scanner/site varia…
View article: Longitudinal associations between language network characteristics in the infant brain and school-age reading abilities are mediated by early-developing phonological skills
Longitudinal associations between language network characteristics in the infant brain and school-age reading abilities are mediated by early-developing phonological skills Open
Reading acquisition is a prolonged learning process relying on language development starting in utero. Behavioral longitudinal studies reveal prospective associations between infant language abilities and preschool/kindergarten phonologica…
View article: Site effects removing and signal enhancement using dual-projection based ICA model
Site effects removing and signal enhancement using dual-projection based ICA model Open
Combining magnetic resonance imaging (MRI) data from multi-site studies is a popular approach for constructing larger datasets to greatly enhance the reliability and reproducibility of neuroscience research. However, the scanner/site varia…
View article: Site effects depth denoising and signal enhancement using dual-projection based ICA model
Site effects depth denoising and signal enhancement using dual-projection based ICA model Open
Combining magnetic resonance imaging (MRI) data from multi-site studies is a popular approach for constructing larger datasets to greatly enhance the reliability and reproducibility of neuroscience research. However, the scanner/site varia…
View article: Common and distinct roles of amygdala subregional functional connectivity in non-motor symptoms of Parkinson’s disease
Common and distinct roles of amygdala subregional functional connectivity in non-motor symptoms of Parkinson’s disease Open
Neuroimaging studies suggest a pivotal role of amygdala dysfunction in non-motor symptoms (NMS) of Parkinson’s disease (PD). However, the relationship between amygdala subregions (the centromedial (CMA), basolateral (BLA) and superficial a…