Mingsheng Huang
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View article: Decoding tumor heterogeneity with imaging biomarkers predicts response to TACE plus Immunotherapy and targeted therapy in HCC
Decoding tumor heterogeneity with imaging biomarkers predicts response to TACE plus Immunotherapy and targeted therapy in HCC Open
Background & Aims: This study aims to quantify intratumor heterogeneity (ITH) and identify prognostic imaging biomarkers in patients with hepatocellular carcinoma (HCC) treated with transarterial chemoembolization combined with immune chec…
View article: Cyclic cytokines mediated the effect of immune cells on meningioma: a two-step, mediation mendelian randomization study
Cyclic cytokines mediated the effect of immune cells on meningioma: a two-step, mediation mendelian randomization study Open
View article: Pre-emptive TIPS with 8-mm stents reduces hepatic encephalopathy without compromising efficacy in acute variceal bleeding
Pre-emptive TIPS with 8-mm stents reduces hepatic encephalopathy without compromising efficacy in acute variceal bleeding Open
This multicenter study of 470 patients with cirrhosis and acute variceal bleeding shows that pre-emptive transjugular intrahepatic portosystemic shunt (TIPS) placement using 8-mm stents reduces the 1-year incidence of overt hepatic encepha…
View article: TACE Sequential to Radiofrequency Ablation versus RFA Alone in Hepatocellular Carcinoma Within Milan Criteria
TACE Sequential to Radiofrequency Ablation versus RFA Alone in Hepatocellular Carcinoma Within Milan Criteria Open
cTACE-RFA significantly prolongs LPFS compared to RFA alone in early HCC, particularly for tumors >3 cm or in high-risk locations, without increasing major complications.
View article: Predicting chronic stenosis progression of stable coronary artery disease using peri-coronary fat attenuation index derived from coronary computed tomography angiography
Predicting chronic stenosis progression of stable coronary artery disease using peri-coronary fat attenuation index derived from coronary computed tomography angiography Open
Baseline peri-coronary FAI is valuable in predicting chronic coronary stenosis progression that occurs within a short period (within 1 year) in RCA, and, potentially, in LM + CX. Stenosis progression in LAD might be mainly driven by factor…
View article: Donafenib vs. lenvatinib combined with transarterial chemoembolization as initial therapy for unresectable hepatocellular carcinoma: a retrospective real-world study
Donafenib vs. lenvatinib combined with transarterial chemoembolization as initial therapy for unresectable hepatocellular carcinoma: a retrospective real-world study Open
Dona-TACE and LEN-TACE demonstrated comparable efficacy in unresectable HCC, but Dona-TACE exhibited a superior safety profile, suggesting its potential as a preferable option for patients with higher comorbidity risks. Further prospective…
View article: Adaptive Guided Filtering and Spectral-Entropy-Based Non-Uniformity Correction for High-Resolution Infrared Line-Scan Images
Adaptive Guided Filtering and Spectral-Entropy-Based Non-Uniformity Correction for High-Resolution Infrared Line-Scan Images Open
Stripe noise along the scanning direction significantly degrades the quality of high-resolution infrared line-scan images and impairs downstream tasks such as target detection and radiometric analysis. This paper presents a lightweight, si…
View article: TACE Combined with Lenvatinib-PD-1 Versus TACE Monotherapy as Conversion Therapy Before Liver Resection in Unresectable Hepatocellular Carcinoma: A Retrospective, Propensity Score Matching Study
TACE Combined with Lenvatinib-PD-1 Versus TACE Monotherapy as Conversion Therapy Before Liver Resection in Unresectable Hepatocellular Carcinoma: A Retrospective, Propensity Score Matching Study Open
Compared to TACE monotherapy, TACE combined with Lenvatinib-PD-1 inhibitor as conversion therapy can improve long-term survival outcomes in patients with uHCC who undergo subsequent LR, with an acceptable safety profile.
View article: HDF-Net: Hierarchical Dual-Branch Feature Extraction Fusion Network for Infrared and Visible Image Fusion
HDF-Net: Hierarchical Dual-Branch Feature Extraction Fusion Network for Infrared and Visible Image Fusion Open
To enhance scene perception and comprehension, infrared and visible image fusion (IVIF) integrates complementary data from two modalities. However, many existing methods fail to explicitly separate modality-specific and modality-shared fea…
View article: SGLT2 inhibition mitigates intracerebral hemorrhage risk by modulating inflammation
SGLT2 inhibition mitigates intracerebral hemorrhage risk by modulating inflammation Open
Sodium-glucose cotransporter 2 (SGLT-2) inhibitors have been increasingly recognized for their potential neuroprotective properties. Nevertheless, their effects on intracerebral hemorrhage (ICH) are still debated, with the precise mechanis…
View article: Lossy Infrared Image Compression Based on Wavelet Coefficient Probability Modeling and Run-Length-Enhanced Huffman Coding
Lossy Infrared Image Compression Based on Wavelet Coefficient Probability Modeling and Run-Length-Enhanced Huffman Coding Open
Infrared line-scanning images have high redundancy and large file sizes. In JPEG2000 compression, the MQ arithmetic encoder’s complexity slows down processing. Huffman coding can achieve O(1) complexity based on a code table, but its integ…
View article: Idarubicin-transarterial chemoembolization combined with gemcitabine plus cisplatin for unresectable intrahepatic cholangiocarcinoma
Idarubicin-transarterial chemoembolization combined with gemcitabine plus cisplatin for unresectable intrahepatic cholangiocarcinoma Open
BACKGROUND Intrahepatic cholangiocarcinoma (iCCA) is the second most common liver malignancy with poor prognosis and limited treatment options. AIM To identify the most effective drug for transarterial chemoembolization (TACE) in cholangio…
View article: A Low-Complexity Lossless Compression Method Based on a Code Table for Infrared Images
A Low-Complexity Lossless Compression Method Based on a Code Table for Infrared Images Open
Traditional JPEG series image compression algorithms have limitations in speed. To improve the storage and transmission of 14-bit/pixel images acquired by infrared line-scan detectors, a novel method is introduced for achieving high-speed …
View article: An Adaptive Weighted Residual-Guided Algorithm for Non-Uniformity Correction of High-Resolution Infrared Line-Scanning Images
An Adaptive Weighted Residual-Guided Algorithm for Non-Uniformity Correction of High-Resolution Infrared Line-Scanning Images Open
Gain and bias non-uniformities in infrared line-scanning detectors often result in horizontal streak noise, degrading image quality. This paper introduces a novel non-uniformity correction algorithm combining residual guidance and adaptive…
View article: Radiomics models using machine learning algorithms to differentiate the primary focus of brain metastasis
Radiomics models using machine learning algorithms to differentiate the primary focus of brain metastasis Open
The enhanced MRI radiomics model, especially the LightGBM model, can accurately predict the primary lesion types of brain metastases from lung cancer and breast cancer origins.
View article: Automated Three-Dimensional Multi-Tissue Information Fusion Framework in Predicting Postoperative Overt Hepatic Encephalopathy Risk before Transjugular Intrahepatic Portosystemic Shunt: A Multi-Center Study
Automated Three-Dimensional Multi-Tissue Information Fusion Framework in Predicting Postoperative Overt Hepatic Encephalopathy Risk before Transjugular Intrahepatic Portosystemic Shunt: A Multi-Center Study Open
View article: Longitudinal Body Composition Identifies Hepatocellular Carcinoma With Cachexia Following Combined Immunotherapy and Target Therapy (CHANCE2213)
Longitudinal Body Composition Identifies Hepatocellular Carcinoma With Cachexia Following Combined Immunotherapy and Target Therapy (CHANCE2213) Open
Background Cancer cachexia can impact prognosis, cause resistance to anticancer treatments and affect the tolerability of treatments. This study aims to identify hepatocellular carcinoma (HCC) with cachexia by characterizing longitudinal b…
View article: Clinical outcomes of modified transarterial chemoembolization vs. drug-eluting bead transarterial chemoembolization as initial treatment for single hepatocellular carcinoma: a propensity score matching analysis
Clinical outcomes of modified transarterial chemoembolization vs. drug-eluting bead transarterial chemoembolization as initial treatment for single hepatocellular carcinoma: a propensity score matching analysis Open
M-TACE showed higher initial CR rates, lower LTP rates, and extended time to LTP compared to DEB-TACE, indicating its potential to enhance TACE effectiveness for solitary HCC.
View article: Exploring the effect of lifestyle behaviors and socioeconomic status on atrial fibrillation: the mediating role of 91 inflammatory cytokines
Exploring the effect of lifestyle behaviors and socioeconomic status on atrial fibrillation: the mediating role of 91 inflammatory cytokines Open
Background Atrial fibrillation (AF) is one of the most prevalent cardiac arrhythmias and has a significant economic and social burden. Whether it is associated with lifestyle behaviors and socioeconomic status is currently poorly understoo…
View article: The causal effect of gut microbiota on hepatic encephalopathy: a mendelian randomization analysis
The causal effect of gut microbiota on hepatic encephalopathy: a mendelian randomization analysis Open
Our MR study demonstrated a potential causal association between Bifidobacterium, Bifidobacteriaceae, and Bifidobacteriales and HE. This finding may provide new therapeutic targets for patients at risk of HE in the future.
View article: Causal effect of lifestyle and metabolic indicator with herpes zoster: a two-sample Mendelian randomization study
Causal effect of lifestyle and metabolic indicator with herpes zoster: a two-sample Mendelian randomization study Open
Background Previous observational studies have reported certain causal relationships between factors such as smoking, alcohol consumption, obesity, physical activity, metabolic disorders, and the incidence of herpes zoster (HZ). However, t…
View article: Effects of COVID-19 on Heart Failure and Its Risk Factors: A Bidirectional Mendelian Randomization Study
Effects of COVID-19 on Heart Failure and Its Risk Factors: A Bidirectional Mendelian Randomization Study Open
Introduction Previous studies suggest a potential link between COVID-19 and cardiovascular diseases, particularly heart failure (HF), but causal relationships remain unclear. This study uses bidirectional Mendelian randomization (MR) to in…
View article: Role of inflammatory biomarkers in mediating the effect of lipids on spontaneous intracerebral hemorrhage: a two-step, two-sample Mendelian randomization study
Role of inflammatory biomarkers in mediating the effect of lipids on spontaneous intracerebral hemorrhage: a two-step, two-sample Mendelian randomization study Open
Background Spontaneous intracerebral hemorrhage (sICH) is a form of stroke with high mortality rates and significant neurological implications for patients. Abnormalities in lipid metabolism have been implicated in various cardiovascular d…
View article: Hepatic Arterial Infusion Chemotherapy Combined with Lenvatinib and PD-1 Inhibitors for Managing Arterioportal Shunt in Hepatocellular Carcinoma with Portal Vein Tumor Thrombus: A Retrospective Cohort Study
Hepatic Arterial Infusion Chemotherapy Combined with Lenvatinib and PD-1 Inhibitors for Managing Arterioportal Shunt in Hepatocellular Carcinoma with Portal Vein Tumor Thrombus: A Retrospective Cohort Study Open
Combining HAIC with LEN and PD-1 inhibitors proves to be both effective and safe in managing APS in HCC with PVTT, potentially improving patient survival.
View article: Hepatic-associated vascular morphological assessment to predict overt hepatic encephalopathy before TIPS: a multicenter study
Hepatic-associated vascular morphological assessment to predict overt hepatic encephalopathy before TIPS: a multicenter study Open
View article: Immune checkpoint inhibitors and anti-vascular endothelial growth factor antibody/tyrosine kinase inhibitors with or without transarterial chemoembolization as first-line treatment for advanced hepatocellular carcinoma (CHANCE2201): a target trial emulation study
Immune checkpoint inhibitors and anti-vascular endothelial growth factor antibody/tyrosine kinase inhibitors with or without transarterial chemoembolization as first-line treatment for advanced hepatocellular carcinoma (CHANCE2201): a target trial emulation study Open
View article: Causal effects of immune cells in glioblastoma: a Bayesian Mendelian Randomization study
Causal effects of immune cells in glioblastoma: a Bayesian Mendelian Randomization study Open
Background Glioblastoma (GBM) is a highly malignant brain tumor, and immune cells play a crucial role in its initiation and progression. The immune system's cellular components, including various types of lymphocytes, macrophages, and dend…
View article: Can Relative Abundance of Diatoms (RAD) Serve as an Indicator for the Water Quality Assessment in River-Connected Lakes? A Case Study at Dongting Lake
Can Relative Abundance of Diatoms (RAD) Serve as an Indicator for the Water Quality Assessment in River-Connected Lakes? A Case Study at Dongting Lake Open
Abstrat: In this study, 15 sampling sites were set up in Dongting Lake, a typical river-connected lake in China, to investigate water quality and phytoplankton in March, June, September and December from year 2017 to 2022. Seven diatom ind…
View article: One‐year status of hepatic venous pressure gradient measurement from 85 hospitals in China
One‐year status of hepatic venous pressure gradient measurement from 85 hospitals in China Open
Aims Surveys and research on the applications of the hepatic venous pressure gradient (HVPG) are important for understanding the current status and future development of this technology in China. This article aimed to investigate the statu…
View article: Transarterial Chemoembolization (TACE) Combined with Lenvatinib versus TACE Alone in Intermediate-Stage Hepatocellular Carcinoma Patients Beyond Up-To-Seven Criteria: A Retrospective, Propensity Score-Matched Analysis
Transarterial Chemoembolization (TACE) Combined with Lenvatinib versus TACE Alone in Intermediate-Stage Hepatocellular Carcinoma Patients Beyond Up-To-Seven Criteria: A Retrospective, Propensity Score-Matched Analysis Open
Background: To compare the treatment efficacy and safety of transarterial chemoembolization (TACE) combined with lenvatinib versus TACE alone in patients with intermediate-stage hepatocellular carcinoma (HCC) beyond up-to-seven criteria. M…