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View article: Poor Sleep Pattern Might Increase the Prevalence of Abdominal Aortic Calcification in US Adults: Data from the NHANES (2013-2014)
Poor Sleep Pattern Might Increase the Prevalence of Abdominal Aortic Calcification in US Adults: Data from the NHANES (2013-2014) Open
Sleep patterns were related to the risk of AAC in middle-aged and elderly populations. Poor sleep patterns may increase AAC prevalence.
View article: Codimension-two bifurcations of a two-dimensional discrete time Lotka-Volterra predator-prey model
Codimension-two bifurcations of a two-dimensional discrete time Lotka-Volterra predator-prey model Open
In this paper, we investigate the codimension-two bifurcations of a two-dimensional discrete time predator-prey model, which is derived from a classical Lotka-Volterra type predator-prey system by the forward Euler scheme. It is shown that…
View article: Dynamical Behavior of Discrete Ratio-Dependent Predator-Prey System
Dynamical Behavior of Discrete Ratio-Dependent Predator-Prey System Open
In this paper, we propose a discrete ratio-dependent predator-prey system. The stability of the fixed points of this model is studied. At the same time, it is shown that the discrete model undergoes fold bifurcation and flip bifurcation by…
View article: Ferritinophagy-mediated ferroptosis is involved in sepsis-induced cardiac injury
Ferritinophagy-mediated ferroptosis is involved in sepsis-induced cardiac injury Open
Ferroptosis is a reactive oxygen species (ROS)- and iron-dependent form of regulated cell death (RCD), playing critical roles in organ injury and targeting therapy of cancers. Previous studies have demonstrated that ferroptosis participate…
View article: Andrographolide Protects Against Adverse Cardiac Remodeling After Myocardial Infarction through Enhancing Nrf2 Signaling Pathway
Andrographolide Protects Against Adverse Cardiac Remodeling After Myocardial Infarction through Enhancing Nrf2 Signaling Pathway Open
Adverse cardiac remodeling after myocardial infarction (MI) is associated with extremely high mortality rates worldwide. Although optimized medical therapy, Preservation of lusitropic and inotropic function and protection against adverse r…
View article: The 5-Lipoxygenase Inhibitor Zileuton Protects Pressure Overload-Induced Cardiac Remodeling via Activating PPAR<i>α</i>
The 5-Lipoxygenase Inhibitor Zileuton Protects Pressure Overload-Induced Cardiac Remodeling via Activating PPAR<i>α</i> Open
Zileuton has been demonstrated to be an anti-inflammatory agent due to its well-known ability to inhibit 5-lipoxygenase (5-LOX). However, the effects of zileuton on cardiac remodeling are unclear. In this study, the effects of zileuton on …
View article: Andrographolide Protects against HG-Induced Inflammation, Apoptosis, Migration, and Impairment of Angiogenesis via PI3K/AKT-eNOS Signalling in HUVECs
Andrographolide Protects against HG-Induced Inflammation, Apoptosis, Migration, and Impairment of Angiogenesis via PI3K/AKT-eNOS Signalling in HUVECs Open
Andrographolide (Andr) is a major component isolated from the plant Andrographis paniculata . Inflammation, apoptosis, and impaired angiogenesis are implicated in the pathogenesis of high glucose (HG)-induced injury of vascular endothelioc…
View article: Zingerone attenuates aortic banding‐induced cardiac remodelling via activating the eNOS/Nrf2 pathway
Zingerone attenuates aortic banding‐induced cardiac remodelling via activating the eNOS/Nrf2 pathway Open
Cardiac remodelling refers to a series of changes in the size, shape, wall thickness and tissue structure of the ventricle because of myocardial injury or increased pressure load. Studies have shown that cardiac remodelling plays a signifi…
View article: Cordycepin ameliorates cardiac hypertrophy via activating the AMPKα pathway
Cordycepin ameliorates cardiac hypertrophy via activating the AMPKα pathway Open
Increase of myocardial oxidative stress is closely related to the occurrence and development of cardiac hypertrophy. Cordycepin, also known as 3'‐deoxyadenosine, is a natural bioactive substance extracted from Cordyceps militaris (which is…
View article: STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3
STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3 Open
Mountainous evidence suggests that inflammation, cardiomyocyte apoptosis and pyroptosis are involved in the development of sepsis and sepsis-induced cardiomyopathy (SIC). Stimulator of interferon genes (STING) is an indispensable molecule …
View article: Aucubin protects against pressure overload‐induced cardiac remodelling <i>via</i> the β<sub>3</sub>‐adrenoceptor–neuronal NOS cascades
Aucubin protects against pressure overload‐induced cardiac remodelling <i>via</i> the β<sub>3</sub>‐adrenoceptor–neuronal NOS cascades Open
Background and Purpose Aucubin, the predominant component of Eucommia ulmoides Oliv., has been shown to have profound effects on oxidative stress. As oxidative stress has previously been demonstrated to contribute to acute and chronic myoc…
View article: Erratum: Aucubin Protects against TGFβ1-Induced Cardiac Fibroblasts Activation by Mediating the AMPKα/mTOR Signaling Pathway
Erratum: Aucubin Protects against TGFβ1-Induced Cardiac Fibroblasts Activation by Mediating the AMPKα/mTOR Signaling Pathway Open
Correction to: Aucubin Protects against TGFβ1-Induced Cardiac Fibroblasts Activation by Mediating the AMPKα/mTOR Signaling PathwayPlanta Med 2018; 84(02): 91-99DOI: 10.1055/s-0043-118663