Mengqi Xu
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View article: The interplay between M2-like macrophages and Th17.1 cells promotes the progression of early-stage sarcoidosis
The interplay between M2-like macrophages and Th17.1 cells promotes the progression of early-stage sarcoidosis Open
Our study reveals a novel interaction between Th17.1 cells and M2-like macrophages in Type III granulomas potentially mediated through CD47-SIRPα, which may contribute to impaired antigen processing and glucocorticoid resistance in sarcoid…
View article: Exploring challenges to medication adherence aacmong young and middle-aged adults with coronary heart disease in China: a qualitative study
Exploring challenges to medication adherence aacmong young and middle-aged adults with coronary heart disease in China: a qualitative study Open
Background Although coronary heart disease (CHD) is becoming increasingly common among young and middle-aged adults, their outcomes usually remain suboptimal. One major contributing factor is poor medication adherence. This study aims to e…
View article: Visualization of <scp>OPN</scp> ‐Targeted Self‐Assembled Micelles Encapsulated With an <scp>SIRT6</scp> Activator and Doped Indocyanine Green for Attenuating Vascular Aging
Visualization of <span>OPN</span> ‐Targeted Self‐Assembled Micelles Encapsulated With an <span>SIRT6</span> Activator and Doped Indocyanine Green for Attenuating Vascular Aging Open
Objectives Sirtuin 6 (SIRT6) is a longevity‐associated gene with recognized therapeutic potential for vascular aging through the regulation of vascular smooth muscle cells (VSMCs) senescence. This study aims to develop a visualized nanodel…
View article: Study on Early Warning of Stiffness Degradation and Collapse of Steel Frame Under Fire
Study on Early Warning of Stiffness Degradation and Collapse of Steel Frame Under Fire Open
Frequent building fires seriously threaten the safety of steel structures. According to the data, fire accidents account for about 35% of the total number of production safety accidents. The collapse of steel structures accounted for 42% o…
View article: Characteristics of Lower Extremity Kinematics, Kinetics, and Muscle Activity in Individuals With Chronic Ankle Instability During Landing With Expected and Unexpected Inversion Perturbations: A Systematic Review and Meta‐Analysis
Characteristics of Lower Extremity Kinematics, Kinetics, and Muscle Activity in Individuals With Chronic Ankle Instability During Landing With Expected and Unexpected Inversion Perturbations: A Systematic Review and Meta‐Analysis Open
Objective This study aims to investigate whether alterations in the lower extremity kinematics, kinetics, and muscle activity of individuals with chronic ankle instability (CAI) occur during landing with expected and unexpected inversion p…
View article: Understanding Medication Self-Management at Home Among Older Adults with Coronary Artery Disease: A Qualitative Study
Understanding Medication Self-Management at Home Among Older Adults with Coronary Artery Disease: A Qualitative Study Open
Older adults with coronary artery disease struggled with seeking information to adapt to the new regimens and exploring different strategies to improve their adherence. Future interventions could improve their medication self-efficacy thro…
View article: Case Study of PLC Synchronous Lifting Technology in Concrete Column Reinforcement: Design, Construction, and Monitoring
Case Study of PLC Synchronous Lifting Technology in Concrete Column Reinforcement: Design, Construction, and Monitoring Open
Traditional support methods, such as full-frame scaffolding, often pose significant safety risks during the replacement of defective concrete. In contrast, the application of programmable logic controller (PLC) synchronous jacking technolo…
View article: The Intracerebral Haemorrhage in Patients With Dengue Fever: A Systematic Review and Meta‐Analysis
The Intracerebral Haemorrhage in Patients With Dengue Fever: A Systematic Review and Meta‐Analysis Open
Dengue virus is a neurotropic virus capable of infecting the supporting cells of the central nervous system. One of the most severe neurological consequences of this infection is intracerebral haemorrhage, which is a leading cause of death…
View article: Study on the Shear Characteristics of the Frozen Soil–Concrete Interface at Different Roughness Levels
Study on the Shear Characteristics of the Frozen Soil–Concrete Interface at Different Roughness Levels Open
The shear characteristics of the frozen soil–concrete interface are core parameters in frost heave resistance design in cold-region engineering, and the influence mechanism of interface roughness on these characteristics is not clear. In t…
View article: Prevalence and risk factors for antenatal anxiety in the first trimester among Chinese pregnant women
Prevalence and risk factors for antenatal anxiety in the first trimester among Chinese pregnant women Open
Background Antenatal anxiety (AA) is a common mental disorder during pregnancy and adversely affects the well-being of both pregnant women and their offspring. The prevalence of AA is exceptionally high in the first trimester, yet there is…
View article: Numerical Simulation and Analysis of Micropile-Raft Joint Jacking Technology for Rectifying Inclined Buildings Due to Uneven Settlement
Numerical Simulation and Analysis of Micropile-Raft Joint Jacking Technology for Rectifying Inclined Buildings Due to Uneven Settlement Open
To address the issue of structural tilting caused by uneven foundation settlement in soft soil areas, this study combined a specific engineering case to conduct numerical simulations of the rectification process for an inclined reinforced …
View article: Laboratory Investigation and Mechanical Evaluation on Xanthan Gum-Reinforced Clay: Unconfined Compression Test, Triaxial Shear Test, and Microstructure Characterization
Laboratory Investigation and Mechanical Evaluation on Xanthan Gum-Reinforced Clay: Unconfined Compression Test, Triaxial Shear Test, and Microstructure Characterization Open
Xanthan gum (XG) has potential application prospects as a biopolymer in soil reinforcement engineering. However, there remains a lack of relevant research on its influence on the mechanical properties, microscopic mechanism, and pH value c…
View article: Probiotic potential of Phocaeicola coprocola in modulating learning and memory behaviors in the honeybee model
Probiotic potential of Phocaeicola coprocola in modulating learning and memory behaviors in the honeybee model Open
Introduction Gut microbial therapy has emerged as a prominent research topic for brain function and disorders. The depletion of Phocaeicola coprocola has been reported in various brain-related conditions, suggesting its possible neuroprote…
View article: Removal effect of recycled solid wastes and clay minerals on graphene oxide from water
Removal effect of recycled solid wastes and clay minerals on graphene oxide from water Open
Graphene oxide (GO), a hydrophilic nanomaterial with a high surface area, offers broad utility in aqueous systems, but poses critical environmental risks due to its stability, persistence, and resistance to degradation. To combat GO-relate…
View article: Correction: Xie et al. Investigating Fire Collapse Early Warning Systems for Portal Frames. Buildings 2025, 15, 296
Correction: Xie et al. Investigating Fire Collapse Early Warning Systems for Portal Frames. Buildings 2025, 15, 296 Open
Insert the reference [...]
View article: The Yarkand hare epidermal growth factor receptor improves the survival and antioxidant capacity of HeLa cells under stress
The Yarkand hare epidermal growth factor receptor improves the survival and antioxidant capacity of HeLa cells under stress Open
Epidermal growth factor receptor (EGFR) is one of the most important tyrosine kinase receptor families, which plays a pivotal role in cell signaling transduction and physiological processes. Studies on the EGFR gene in humans and other spe…
View article: Regulatable C-X-C chemokine receptor type 4 in iPSC-derived NK cells improves bone marrow chemotaxis and targeting resident tumor
Regulatable C-X-C chemokine receptor type 4 in iPSC-derived NK cells improves bone marrow chemotaxis and targeting resident tumor Open
iPSC-derived natural killer cells (iNKs) have emerged as a promising cellular therapy, especially for the refractory or relapsed acute myeloid leukemia (R/R AML) patients, but limited research focused on the chemotaxis of iNKs. Here we dem…
View article: Honeybees fed D-galactose exhibit aging signs with changes in gut microbiota and metabolism
Honeybees fed D-galactose exhibit aging signs with changes in gut microbiota and metabolism Open
Honeybees ( Apis mellifera ), as social insects, exhibit complex social behaviors and cognitive functions. The short lifespan and stable gut microorganisms of honeybees provide certain availability as a rapid and high-flux animal model for…
View article: Exploring the relationship between childhood maltreatment and cognitive bias in Chinese adults with major depressive disorder
Exploring the relationship between childhood maltreatment and cognitive bias in Chinese adults with major depressive disorder Open
This study aims to explore how different forms and cumulative experiences of childhood maltreatment (CM) relate to cognitive biases. A total of 121 participants diagnosed with major depressive disorder (MDD) and 120 healthy controls (HC) w…
View article: Investigating Fire Collapse Early Warning Systems for Portal Frames
Investigating Fire Collapse Early Warning Systems for Portal Frames Open
In recent years, firefighter accidents and people injured by the collapse of steel structures during a fire have occurred frequently, which has attracted the attention of the National Emergency Management Department and the Fire and Rescue…
View article: Cumulative effects of stress-sensitivity factors on depressive symptoms and suicide risk: A prospective study
Cumulative effects of stress-sensitivity factors on depressive symptoms and suicide risk: A prospective study Open
BACKGROUND Sensitivity to stress is essential in the onset, clinical symptoms, course, and prognosis of major depressive disorder (MDD). Meanwhile, it was unclear how variously classified but connected stress-sensitivity variables affect M…
View article: The R Package WMAP: Tools for Causal Meta-Analysis by Integrating Multiple Observational Studies
The R Package WMAP: Tools for Causal Meta-Analysis by Integrating Multiple Observational Studies Open
Integrating multiple observational studies for meta-analysis has sparked much interest. The presented R package WMAP (Weighted Meta-Analysis with Pseudo-Population) addresses a critical gap in the implementation of integrative weighting ap…
View article: CD70-targeted iPSC-derived CAR-NK cells display potent function against tumors and alloreactive T cells
CD70-targeted iPSC-derived CAR-NK cells display potent function against tumors and alloreactive T cells Open
Clinical application of autologous chimeric antigen receptor (CAR)-T cells is complicated by limited targeting of cancer types, as well as the time-consuming and costly manufacturing process. We develop CD70-targeted, induced pluripotent s…
View article: Research on the Mechanical Properties of Elliptical Negative Poisson’s Ratio Structures
Research on the Mechanical Properties of Elliptical Negative Poisson’s Ratio Structures Open
A negative Poisson’s ratio structure has special deformation behavior and energy absorption characteristics, and is a new structure with broad application prospects. However, most of the current research is still at the micro theoretical l…
View article: Critical review on graphene oxide modified geopolymers: Dispersion preparation, mechanical properties, and microscopic mechanisms
Critical review on graphene oxide modified geopolymers: Dispersion preparation, mechanical properties, and microscopic mechanisms Open
In recent years, graphene oxide (GO) has been widely used in various fields owing to its high specific surface area and rich oxygen-containing functional groups. Adding an appropriate amount of GO (about 0.01–0.1 wt%) is beneficial to stre…
View article: Study on Fractal Damage of Concrete Cracks Based on U-Net
Study on Fractal Damage of Concrete Cracks Based on U-Net Open
The damage degree of a reinforced concrete structure is closely related to the generation and expansion of cracks. However, the traditional damage assessment methods of reinforced concrete structures have defects, including low efficiency …
View article: Educational programmes for improving medication adherence among older adults with coronary artery disease: A systematic review and meta-analysis
Educational programmes for improving medication adherence among older adults with coronary artery disease: A systematic review and meta-analysis Open
PROSPERO (Registration Number: CRD42024472344; Registration name: Educational programmes for improving medication adherence among older adults with coronary artery disease: A systematic review).
View article: Modeling and application of urban waterlogging resilience assessment based on PSR–NES framework and analysis of driving mechanisms
Modeling and application of urban waterlogging resilience assessment based on PSR–NES framework and analysis of driving mechanisms Open
Extreme weather events are escalating globally, intensifying urban waterlogging disasters and endangering inhabitants and assets while hindering socio-economic progress. This study explores factors hindering cities' waterlogging disaster m…