Mingxin He
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View article: Formation of gut microbiota and application of microecological regulators in children
Formation of gut microbiota and application of microecological regulators in children Open
The initial bacteria in a newborn's gastrointestinal tract come from the mother's birth canal, the environment, and breast milk. Gut microbiota is established earlier in infants delivered naturally than by cesarean section (C-section). Gut…
View article: Novel Loop-Structure-Based CD19/CD22 Dual-Target CAR-T Therapy for High-Risk Diffuse Large B-Cell Lymphoma Presenting with Hemophagocytic Lymphohistiocytosis: A Case Report
Novel Loop-Structure-Based CD19/CD22 Dual-Target CAR-T Therapy for High-Risk Diffuse Large B-Cell Lymphoma Presenting with Hemophagocytic Lymphohistiocytosis: A Case Report Open
The novel CD19/CD22 BS LoopCAR-T therapy is safe and effective in treating high-risk DLBCL patients presenting with HLH.
View article: Shaping oral and intestinal microbiota and the immune system during the first 1,000 days of life
Shaping oral and intestinal microbiota and the immune system during the first 1,000 days of life Open
The first 1, 000 days of life, from the fetal stage of a woman's pregnancy to 2 years of age after the baby is born, is a critical period for microbial colonization of the body and development of the immune system. The immune system and mi…
View article: In vitro functional validation of anti-CD19 chimeric antigen receptor T cells expressing lysine-specific demethylase 1 short hairpin RNA for the treatment of diffuse large B cell lymphoma
In vitro functional validation of anti-CD19 chimeric antigen receptor T cells expressing lysine-specific demethylase 1 short hairpin RNA for the treatment of diffuse large B cell lymphoma Open
Background Chimeric antigen receptor T (CAR-T) cell therapy is more effective in relapsed or refractory diffuse large B cell lymphoma (DLBCL) than other therapies, but a high proportion of patients relapse after CAR-T cell therapy owing to…
View article: Completion of Waste Heat Recovery and CO2 Conversion Simultaneously Based on the Flue Gas Chemical Recuperative Cycle: A Review
Completion of Waste Heat Recovery and CO2 Conversion Simultaneously Based on the Flue Gas Chemical Recuperative Cycle: A Review Open
Energy shortage and greenhouse gas emission have become bottlenecks in current society development. Improving the efficiency of energy conversion and utilization systems through waste heat recovery and reduction of greenhouse gas through C…
View article: The role of fecal microbiota transplantation in the treatment of acute graft-versus-host disease
The role of fecal microbiota transplantation in the treatment of acute graft-versus-host disease Open
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is one of the most important methods for treating a wide range of hematologic malignancies and bone marrow failure diseases. However, graft-versus-host disease (GVHD), a major …
View article: Chinese guidelines for integrated diagnosis and treatment of intestinal microecology technologies in tumor application (2024 Edition)
Chinese guidelines for integrated diagnosis and treatment of intestinal microecology technologies in tumor application (2024 Edition) Open
Intestinal microecology (IM) is the largest and most important microecological system of the human body. Furthermore, it is the key factor for activating and maintaining the physiological functions of the intestine. Numerous studies have i…
View article: Exergy analysis and improvement of helium internal purifier
Exergy analysis and improvement of helium internal purifier Open
Exergy analysis was applied to the evaluation of helium internal purifier in this paper. The important operating parameters has been given to determine the exergy destructions in components as well as in the entire cycle of internal purifi…
View article: Therapeutic potential of elafin in airway inflammatory disease
Therapeutic potential of elafin in airway inflammatory disease Open
Elafin, which is derived from trappin-2 or pre-elafin by proteolysis, is an endogenous serine protease inhibitor with a low molecular weight. Its inhibitory activity is dependent on anchoring to the extracellular matrix by forming covalent…
View article: Chinese expert consensus on the management of patients with hematologic malignancies infected with SARS-CoV-2
Chinese expert consensus on the management of patients with hematologic malignancies infected with SARS-CoV-2 Open
In December 2022, the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) became dominant in China due to its high infectivity and lower mortality rate. The risk of critical illness and mortality among patients …
View article: Oral Pathogenic Bacteria and the Oral–Gut–Liver Axis: A New Understanding of Chronic Liver Diseases
Oral Pathogenic Bacteria and the Oral–Gut–Liver Axis: A New Understanding of Chronic Liver Diseases Open
Liver diseases have long been a prevalent cause of morbidity and mortality, and their development and progression involve multiple vital organs throughout the body. Recent studies on the oral–gut–liver axis have revealed that the oral micr…
View article: Chinese expert consensus on intestinal microecology and management of digestive tract complications related to tumor treatment (version 2022)
Chinese expert consensus on intestinal microecology and management of digestive tract complications related to tumor treatment (version 2022) Open
The human gut microbiota represents a complex ecosystem that is composed of bacteria, fungi, viruses, and archaea. It affects many physiological functions including metabolism, inflammation, and the immune response. The gut microbiota also…
View article: Oral Microbiota and Tumor—A New Perspective of Tumor Pathogenesis
Oral Microbiota and Tumor—A New Perspective of Tumor Pathogenesis Open
Microorganisms have long been known to play key roles in the initiation and development of tumors. The oral microbiota and tumorigenesis have been linked in epidemiological research relating to molecular pathology. Notably, some bacteria c…
View article: Myristoylated alanine rich C kinase substrate/Activated Cdc42-associated kinase 1 regulates cortactin to promote neutrophil elastase-induced mucin secretion in airway epithelial cells
Myristoylated alanine rich C kinase substrate/Activated Cdc42-associated kinase 1 regulates cortactin to promote neutrophil elastase-induced mucin secretion in airway epithelial cells Open
Purpose Mucus secretion is excessively increased in airway epithelial cells in pathological states. This process is related to the cytoskeleton and the increase in exocytosis sites, but the movement of secreted molecules and how secretion …
View article: Myrtenol Inhibits Biofilm Formation and Virulence in the Drug-Resistant Acinetobacter baumannii: Insights into the Molecular Mechanisms
Myrtenol Inhibits Biofilm Formation and Virulence in the Drug-Resistant Acinetobacter baumannii: Insights into the Molecular Mechanisms Open
Myrtenol attenuates the BP-AB biofilm formation and virulence by suppressing the expression of bfmR, bap, csuA/B, and ompA.
View article: Characterizing Droplet Retention in Fruit Tree Canopies for Air-Assisted Spraying
Characterizing Droplet Retention in Fruit Tree Canopies for Air-Assisted Spraying Open
As a mainstream spraying technology, air-assisted spraying can increase the penetration and droplet deposition in the tree canopy; however, there seems to be less research on the maximum deposition volume of leaves. In this paper, the maxi…
View article: Two‐Dimensional (2D) or Quasi‐2D Superstructures from DNA‐Coated Colloidal Particles
Two‐Dimensional (2D) or Quasi‐2D Superstructures from DNA‐Coated Colloidal Particles Open
This contribution describes the synthesis of colloidal di‐patch particles functionalized with DNA on the patches and their assembly into colloidal superstructures via cooperative depletion and DNA‐mediated interactions. The assembly into f…
View article: Two‐Dimensional (2D) or Quasi‐2D Superstructures from DNA‐Coated Colloidal Particles
Two‐Dimensional (2D) or Quasi‐2D Superstructures from DNA‐Coated Colloidal Particles Open
This contribution describes the synthesis of colloidal di‐patch particles functionalized with DNA on the patches and their assembly into colloidal superstructures via cooperative depletion and DNA‐mediated interactions. The assembly into f…
View article: Application of delayed luminescence method on measuring of the processing of Chinese herbal materials
Application of delayed luminescence method on measuring of the processing of Chinese herbal materials Open
Background Based on the principle of tradition Chinese medicine, the processing refers to various techniques that alter the overall properties of herbal materials to meet the requirements of therapeutic applications. However, the standards…
View article: Shape‐Shifting Patchy Particles
Shape‐Shifting Patchy Particles Open
A facile method to synthesize shape‐shifting patchy particles on the colloidal scale is described. The design is based on the solvent‐induced shifting of the patch shape between concave and convex features. The initial concave patchy parti…