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View article: Single-cell transcriptomic analysis reveals the heterogeneity and functional characteristics of macrophage subpopulations in colon cancer
Single-cell transcriptomic analysis reveals the heterogeneity and functional characteristics of macrophage subpopulations in colon cancer Open
The Macrophages_SPP1 subtype may contribute to colon cancer progression through metabolic reprogramming and stromal interactions, suggesting that SPP1 and the FTL-SCARA5 axis could represent potential therapeutic targets.
View article: From an Antimicrobial Agent to a constituent of 3D Printed Heterogenous Scaffolds Stimulating Bone Characteristics: An In-vitro and Animal model evaluation
From an Antimicrobial Agent to a constituent of 3D Printed Heterogenous Scaffolds Stimulating Bone Characteristics: An In-vitro and Animal model evaluation Open
3D-printing technologies with 0.1 % K21 represent a significant advancement over conventional regenerative medicine techniques for bone-related treatments.
View article: Pathogenic strains of a gut commensal drive systemic platelet activation and thromboinflammation in lupus nephritis
Pathogenic strains of a gut commensal drive systemic platelet activation and thromboinflammation in lupus nephritis Open
Imbalances in the gut microbiome have been linked to increased intestinal permeability and disease flares in systemic lupus erythematosus (SLE). Our study revealed that patients with flares of lupus nephritis (LN) and intestinal expansions…
View article: Heat Stress Impairs Endometrial Function During Implantation by Regulating Autophagy in Hainan Black Goat
Heat Stress Impairs Endometrial Function During Implantation by Regulating Autophagy in Hainan Black Goat Open
Heat stress (HS) is a significant factor that adversely affects the health, welfare, and productivity of domestic animals, particularly impacting embryo implantation rates. However, the effects of HS on endometrial function during the peri…
View article: Macrophages and pulmonary fibrosis: a bibliometric and visual analysis of publications from 1990 to 2023
Macrophages and pulmonary fibrosis: a bibliometric and visual analysis of publications from 1990 to 2023 Open
Background The role of macrophages in the symptomatic and structural progression of pulmonary fibrosis (PF) has garnered significant scholarly attention in recent years. This study employs a bibliometric approach to examine the present res…
View article: Transcriptomic study of the role of MeFtsZ2-1 in pigment accumulation in cassava leaves
Transcriptomic study of the role of MeFtsZ2-1 in pigment accumulation in cassava leaves Open
MeFtsZ2-1 is a key gene for plant plastid division, but the mechanism by which MeFtsZ2-1 affects pigment accumulation in cassava ( Manihot esculenta Crantz) through plastids remains unclear. We found that MeFtsZ2-1 overexpression in cassav…
View article: Optimization of intraoperative lumpectomy specimen labeling
Optimization of intraoperative lumpectomy specimen labeling Open
BackgroundAccurate lumpectomy specimen orientation is critical as incorrect orientation may result in excision of the wrong lumpectomy margin. Our goal was to determine if specimen orientation achieved by labeling three surfaces is superio…
View article: Identification of the 4CL family in cassava and expression pattern analysis of the Me4CL32 gene
Identification of the 4CL family in cassava and expression pattern analysis of the Me4CL32 gene Open
The 4-coumarate coenzyme A ligase (4CL) plays a critical role in the phenylpropane metabolic pathway and is a key enzyme in plant growth metabolism and stress responses. In this study, 50 Me4CLs were identified within the cassava genome ut…
View article: Transcriptomic Study of the Role of MeFtsZ2-1 in Pigment Accumulation in Cassava Leaves
Transcriptomic Study of the Role of MeFtsZ2-1 in Pigment Accumulation in Cassava Leaves Open
MeFtsZ2-1 is a key gene for plant plastid division, but the mechanism by which MeFtsZ2-1 affects pigment accumulation in cassava ( Manihot esculenta Crantz) through plastids remains unclear. We found that MeFtsZ2-1 overexpression in cassav…
View article: Genome‐wide identification and expression analysis of heat shock protein gene family in cassava
Genome‐wide identification and expression analysis of heat shock protein gene family in cassava Open
Heat shock proteins are important molecular chaperones that are involved in plant growth and stress responses. However, members of the Hsp family have been poorly studied in cassava. In this study, 225 MeHsp genes were identified in the ca…
View article: Supplemental Figures and Figure legends from Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time
Supplemental Figures and Figure legends from Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time Open
This File contains all the supplemental figures and figure legends referred to in the main text.
View article: Supplementary Materials and Methods from Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time
Supplementary Materials and Methods from Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time Open
This file contains the description of supplementary materials and methods that is referred to in the manuscript
View article: Supplemental Figures and Figure legends from Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time
Supplemental Figures and Figure legends from Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time Open
This File contains all the supplemental figures and figure legends referred to in the main text.
View article: Supplementary Materials and Methods from Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time
Supplementary Materials and Methods from Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time Open
This file contains the description of supplementary materials and methods that is referred to in the manuscript
View article: Supplementary Tables from Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time
Supplementary Tables from Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time Open
This file contains 6 supplementary tables referred to in the text of the manuscript
View article: Data from Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time
Data from Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time Open
Treatment strategies with a strong scientific rationale based on specific biomarkers are needed to improve outcomes in patients with advanced sarcomas. Suppression of cell-cycle progression through reactivation of the tumor suppressor reti…
View article: Supplementary Tables from Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time
Supplementary Tables from Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time Open
This file contains 6 supplementary tables referred to in the text of the manuscript
View article: Data from Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time
Data from Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time Open
Treatment strategies with a strong scientific rationale based on specific biomarkers are needed to improve outcomes in patients with advanced sarcomas. Suppression of cell-cycle progression through reactivation of the tumor suppressor reti…
View article: Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time
Sequential Targeting of Retinoblastoma and DNA Synthesis Pathways Is a Therapeutic Strategy for Sarcomas That Can Be Monitored in Real Time Open
Treatment strategies with a strong scientific rationale based on specific biomarkers are needed to improve outcomes in patients with advanced sarcomas. Suppression of cell-cycle progression through reactivation of the tumor suppressor reti…
View article: The prevalence, hospitalization outcomes and risk factors of euthyroid sick syndrome in patients with diabetic ketosis/ketoacidosis
The prevalence, hospitalization outcomes and risk factors of euthyroid sick syndrome in patients with diabetic ketosis/ketoacidosis Open
Background: To investigate the prevalence of euthyroid sick syndrome (ESS) and to evaluate the outcomes and risk factors associated with ESS among hospitalized patients with diabetic ketosis (DK) or diabetic ketoacidosis (DKA). Methods: La…