Minh Arnould
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View article: Novel Chronic Mouse Model of Cerebral Cavernous Malformations
Novel Chronic Mouse Model of Cerebral Cavernous Malformations Open
Background and Purpose— Cerebral cavernous malformations (CCMs) are vascular malformations of the brain that lead to cerebral hemorrhages. A pharmacological treatment is needed especially for patients with nonoperable deep-seated lesions. …
View article: Clinical and Molecular Features of 5 European Multigenerational Families With Moyamoya Angiopathy
Clinical and Molecular Features of 5 European Multigenerational Families With Moyamoya Angiopathy Open
Background and Purpose Moyamoya angiopathy (MMA) is a rare cerebral vasculopathy outside of Asia. In Japanese patients, a vast majority of patients carry the founder p.R4810K variant in the RNF213 gene, and familial cases are around 10%. I…
View article: Network-based analysis of omics data: the LEAN method
Network-based analysis of omics data: the LEAN method Open
Motivation Most computational approaches for the analysis of omics data in the context of interaction networks have very long running times, provide single or partial, often heuristic, solutions and/or contain user-tuneable parameters. Res…