Mi‐Jeong Ahn
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View article: Anti-Helicobacter pylori Compounds of Sambucus williamsii Hance Branch
Anti-Helicobacter pylori Compounds of Sambucus williamsii Hance Branch Open
Sambucus williamsii Hance (Viburnaceae), the Korean elderberry, is widely used in herbal medicine and in the food industry. It is known to have various pharmacological effects, including antitumor, antioxidant, anti-inflammatory, and antim…
View article: Anti-Helicobacter pylori and Anti-Inflammatory Sesquiterpenoids from the Rhizoma of Atractylodes macrocephala
Anti-Helicobacter pylori and Anti-Inflammatory Sesquiterpenoids from the Rhizoma of Atractylodes macrocephala Open
Helicobacter pylori, a spiral-shaped bacterium found in the stomach, is associated with various gastrointestinal and systemic health conditions. Effective suppression of H. pylori is therefore critical for managing gastrointestinal disease…
View article: Anti-cancer effects of wistin on malignant melanoma cells
Anti-cancer effects of wistin on malignant melanoma cells Open
Malignant melanoma (MM) is a severe skin cancer that arises from melanocytes, primarily caused by exposure to ultraviolet radiation. Although MM occurs less frequently than other skin cancers, its metastasis is easily activated, leading to…
View article: Discovery of Isograndidentatin D, a Novel Phenolic Glycoside, and Anti-Helicobacter pylori Phenolics from Salix koreensis Twigs
Discovery of Isograndidentatin D, a Novel Phenolic Glycoside, and Anti-Helicobacter pylori Phenolics from Salix koreensis Twigs Open
Salix koreensis Anderss (Salicaceae), commonly referred to as Korean willow, is native to East Asia, particularly Korea and China, and it has been used in traditional Korean folk medicine for its potent anti-inflammatory, analgesic, and an…
View article: Deodeokaloid, a New Indole Alkaloid N-Glycoside and Bioactive Phenolic Compounds from the Roots of Codonopsis lanceolata
Deodeokaloid, a New Indole Alkaloid N-Glycoside and Bioactive Phenolic Compounds from the Roots of Codonopsis lanceolata Open
Codonopsis lanceolata, commonly known as the bonnet bellflower or deodeok, is primarily found in Eastern Asia. Its roots have been used traditionally across Asia to treat various ailments such as bronchitis, coughs, asthma, and inflammatio…
View article: Activation of Nuclear Factor Erythroid 2-Related Factor-2 by Oxylipin from Mangifera indica Leaves
Activation of Nuclear Factor Erythroid 2-Related Factor-2 by Oxylipin from Mangifera indica Leaves Open
Mangifera indica L., a member of the Anacardiaceae family, is widely cultivated across the globe. The leaves of M. indica are renowned for their medicinal properties, attributed to the abundance of bioactive compounds. This study investiga…
View article: Preparation and characterization of citreorosein nanoparticles with improved bioavailability and cytotoxic potential
Preparation and characterization of citreorosein nanoparticles with improved bioavailability and cytotoxic potential Open
The present study was designed to improve the aqueous solubility and dissolution rate of citreorosein, a poorly water soluble drug, by producing its nanoparticles (NPs) using an “antisolvent precipitation with a syringe pump” (APSP) method…
View article: Chaenomelin, a New Phenolic Glycoside, and Anti-Helicobacter pylori Phenolic Compounds from the Leaves of Salix chaenomeloides
Chaenomelin, a New Phenolic Glycoside, and Anti-Helicobacter pylori Phenolic Compounds from the Leaves of Salix chaenomeloides Open
Salix chaenomeloides Kimura, commonly known as pussy willow, is a deciduous shrub and tree belonging to the Salicaceae family. The genus Salix spp. has been known as a healing herb for the treatment of fever, inflammation, and pain relief.…
View article: Antioxidant and Anti-inflammatory Activities of Rumex acetosa
Antioxidant and Anti-inflammatory Activities of Rumex acetosa Open
Rumex acetosa is a folk medicine for gastritis and gastric ulcers. In our previous study, the ethanol extract of R. acetosa inhibited gastric ulcers and protected gastric tissue in mice induced with HCl/ethanol from gastric ulcers. Moreove…
View article: Anti-<i>Helicobacter pylori</i> Activity of Six Major Compounds Isolated from <i>Rumex acetosa</i>
Anti-<i>Helicobacter pylori</i> Activity of Six Major Compounds Isolated from <i>Rumex acetosa</i> Open
Gastric problems are often caused by the well-known Helicobacter pylori (H. pylori) bacterium. One of the biggest obstacles to the treatment of H. pylori infections is increasing the antibiotic resistance. During our search for naturally d…
View article: Preparation, Characterization, and Evaluation of Physcion Nanoparticles for Enhanced Oral Bioavailability: An Attempt to Improve Its Antioxidant and Anticancer Potential
Preparation, Characterization, and Evaluation of Physcion Nanoparticles for Enhanced Oral Bioavailability: An Attempt to Improve Its Antioxidant and Anticancer Potential Open
This study aims to enhance the dissolution rate of a poorly water-soluble drug physcion by producing its nanoparticles (NPs) using an antisolvent precipitation with a syringe pump (APSP) method and to assess its antioxidant and cytotoxic p…
View article: Modulation of Apoptosis and Autophagy by Melatonin in Juglone-Exposed Bovine Oocytes
Modulation of Apoptosis and Autophagy by Melatonin in Juglone-Exposed Bovine Oocytes Open
Melatonin, an antioxidant hormone secreted by the pineal gland, has been recognized as a regulator for numerous biological events. The deleterious effects of juglone, a polyphenolic extract of walnut trees, on embryo development has been p…
View article: Downregulation of PI3K/AKT/mTOR Pathway in Juglone-Treated Bovine Oocytes
Downregulation of PI3K/AKT/mTOR Pathway in Juglone-Treated Bovine Oocytes Open
We have previously reported that juglone, a natural compound found in Juglandaceae with a wide range of biological activities, can reduces the developmental competence of bovine oocytes. In the current study, we investigated the possible m…
View article: Retraction Note to: Changes in Carotenoid and Anthocyanin Contents, as well as Antioxidant Activity during Storage of Lettuce
Retraction Note to: Changes in Carotenoid and Anthocyanin Contents, as well as Antioxidant Activity during Storage of Lettuce Open
Woo Sung Park, Hye Jin Kim, Hye-Jin Chung, Man Seog Chun, Seong Tae Kim, Seung Yeon Seo, Seong Ho Lim, Yeong Hak Jeong, Jeewon Chun, Sun Kyoung An, and Mi-Jeong Ahn. Journal of the Korean Society of Food Science and Nutrition 2022;51:1370.…
View article: Biochemical Characterization of Orange-Colored Rice Calli Induced by Target Mutagenesis of OsOr Gene
Biochemical Characterization of Orange-Colored Rice Calli Induced by Target Mutagenesis of OsOr Gene Open
We generated an orange-colored (OC) rice callus line by targeted mutagenesis of the orange gene (OsOr) using the CRISPR-Cas9 system. The OC line accumulated more lutein, β-carotene, and two β-carotene isomers compared to the WT callus line…
View article: Antioxidant Constituents and Activities of the Pulp with Skin of Korean Tomato Cultivars
Antioxidant Constituents and Activities of the Pulp with Skin of Korean Tomato Cultivars Open
Tomato is a widely distributed, cultivated, and commercialized vegetable crop. It contains antioxidant constituents including lycopene, tocopherols, vitamin C, γ-aminobutyric acid, phenols, and flavonoids. This study determined the content…
View article: Afrormosin exerts an anticancer effect via MAPK and AKT signaling pathways in B16F10 cells
Afrormosin exerts an anticancer effect via MAPK and AKT signaling pathways in B16F10 cells Open
Melanoma is a deadly skin cancer with high mortality, and its incidence is increasing every year. Although numerous anticancer drugs have been developed, these treatments have various side effects, such as skin rash, fatigue, diarrhea, cou…
View article: Assessment of antioxidant and cytotoxic potential of silver nanoparticles synthesized from root extract of Reynoutria japonica Houtt
Assessment of antioxidant and cytotoxic potential of silver nanoparticles synthesized from root extract of Reynoutria japonica Houtt Open
Free radicals, mostly consist of reactive oxygen species, are generated in human body by several exogenous and endogenous systems. Overproduction of free radicals is known to cause several degenerative disorders including cancer. The aim o…
View article: Wistin Exerts an Anti-Inflammatory Effect via Nuclear Factor-κB and p38 Signaling Pathways in Lipopolysaccharide-Stimulated RAW264.7 Cells
Wistin Exerts an Anti-Inflammatory Effect via Nuclear Factor-κB and p38 Signaling Pathways in Lipopolysaccharide-Stimulated RAW264.7 Cells Open
Inflammation is an immune response to cellular damage caused by various stimuli (internal or external) and is essential to human health. However, excessive inflammatory responses may be detrimental to the host. Considering that the existin…
View article: Labdane-type Diterpenes from<i>Pinus eldarica</i>Needles and Their Anti-<i>Helicobacter pylori</i>Activity
Labdane-type Diterpenes from<i>Pinus eldarica</i>Needles and Their Anti-<i>Helicobacter pylori</i>Activity Open
Pinus eldarica is a medicinal tree used in traditional herbal medicine for the treatment of bronchial asthma and various skin diseases. As part of our ongoing search for bioactive phytochemicals with novel structures in natural products, w…
View article: Chemical Investigation of <i>Tetradium ruticarpum</i> Fruits and Their Antibacterial Activity against <i>Helicobacter pylori</i>
Chemical Investigation of <i>Tetradium ruticarpum</i> Fruits and Their Antibacterial Activity against <i>Helicobacter pylori</i> Open
The fruit of Tetradium ruticarpum, known as Evodiae Fructus, is a traditional herbal medicine used to treat gastric and duodenal ulcers, vomiting, and diarrhea. The traditional usage can be potentially associated with the antibacterial act…
View article: Structural Characterization of Withanolide Glycosides from the Roots of Withania somnifera and Their Potential Biological Activities
Structural Characterization of Withanolide Glycosides from the Roots of Withania somnifera and Their Potential Biological Activities Open
Withania somnifera (Solanaceae), commonly known as “ashwagandha”, is an ayurvedic medicinal plant that has been used for promoting good health and longevity. As part of our ongoing natural product research for the discovery of bioactive ph…
View article: Identification of Antibacterial Sterols from Korean Wild Mushroom Daedaleopsis confragosa via Bioactivity- and LC-MS/MS Profile-Guided Fractionation
Identification of Antibacterial Sterols from Korean Wild Mushroom Daedaleopsis confragosa via Bioactivity- and LC-MS/MS Profile-Guided Fractionation Open
As part of an ongoing natural product chemical research for the discovery of bioactive secondary metabolites with novel structures, wild fruiting bodies of Daedaleopsis confragosa were collected and subjected to chemical and biological ana…
View article: Fraxinol Stimulates Melanogenesis in B16F10 Mouse Melanoma Cells through CREB/MITF Signaling
Fraxinol Stimulates Melanogenesis in B16F10 Mouse Melanoma Cells through CREB/MITF Signaling Open
Melanin pigment produced in melanocytes plays a protective role against ultraviolet radiation. Selective destruction of melanocytes causes chronic depigmentation conditions such as vitiligo, for which there are very few specific medical tr…
View article: Medicarpin Increases Antioxidant Genes by Inducing NRF2 Transcriptional Level in HeLa Cells
Medicarpin Increases Antioxidant Genes by Inducing NRF2 Transcriptional Level in HeLa Cells Open
The nuclear factor erythroid-derived 2-related factor 2 (NRF2) plays a pivotal role in the regulation of genes involved in oxidative stress and drug detoxification. Therefore, it is important to find NRF2 inducers to protect cells from exc…
View article: First Chemical Investigation of Korean Wild Mushroom, Amanita hemibapha subsp. javanica and the Identification of Anti-Helicobacter pylori Compounds
First Chemical Investigation of Korean Wild Mushroom, Amanita hemibapha subsp. javanica and the Identification of Anti-Helicobacter pylori Compounds Open
Amanita hemibapha subsp. javanica (Amanitaceae) is an edible Korean wild mushroom. A. hemibapha subsp. javanica is often confused with A. subjunquillea, known as the East Asian death cap, which is potentially fatal when ingested. This stud…