Explanipedia

Association between urinary DINCH concentration and rheumatoid arthritis: A cross-sectional study Open

Xiangru Liu, Qianyun Chen, Han Zhong, Ying Huang, Bin Yang · 2025

Optimization of meropenem dosing regimens in critically ill patients with augmented renal clearance Open

Jinfeng Luo, Jing Liu, Hongfu Lin, Yang Yang, Caihong Chen , et al. · 2025

The pharmacokinetics of meropenem are significantly altered in patients with augmented renal clearance (ARC), resulting in suboptimal plasma concentrations. The objective of this study is to investigate the efficacy of different meropenem …

The C-reactive protein (CRP)-albumin-lymphocyte (CALLY) index exhibits an L-shaped association with all-cause mortality in rheumatoid arthritis patients: a retrospective cohort study Open

Jialin Zhang, Yanhua Lin, Jingyan Zeng, Guihu Luo, Pan Liao , et al. · 2025

Integrating 2D magnets for quantum devices: from materials and characterization to future technology Open

Han Zhong, Douglas Z. Plummer, P.-C. Lu, Yang Li, Polina Leger , et al. · 2025

The unveiling of two-dimensional (2D) van der Waals magnetism ignited a surge of interest in low-dimensional magnetism. With dimensions reduced, research has delved into facile electric control of 2D magnetism, high-quality heterostructure…

Economic burden of hepatitis B patients and its influencing factors in China: a systematic review Open

Mengxia Yan, H. Ye, Ying Chen, Huajie Jin, Han Zhong , et al. · 2024

Hepatitis B has caused a huge economic burden on Chinese society, and hidden costs also respond to a great psychological burden on patients and their families. Based on existing studies, there is an urgent need for high-quality, multicente…

Integrating 2D Magnets for Quantum Devices: from Materials and Characterization to Future Technology Open

Han Zhong, Douglas Z. Plummer, P.-C. Lu, Yang Li, Polina A. Leger , et al. · 2024

The unveiling of 2D van der Waals magnetism in 2017 ignited a surge of interest in low-dimensional magnetism. With dimensions reduced, research has delved into facile electric control of 2D magnetism, high-quality heterostructure design, a…

LPS-induced monocarboxylate transporter-1 inhibition facilitates lactate accumulation triggering epithelial-mesenchymal transformation and pulmonary fibrosis Open

Jinhua Feng, Han Zhong, Shuya Mei, Ri Tang, Yang Zhou , et al. · 2024

Integrin β3 Mediates Sepsis and Mechanical Ventilation-Associated Pulmonary Fibrosis Through Glycometabolic Reprogramming Open

Shuya Mei, Ri Tang, Yue Hu, Jinhua Feng, Qiaoyi Xu , et al. · 2023

Phosphorylcholine-grafted graphene oxide loaded with irinotecan for potential oncology therapy Open

Jia Cui, Ziyi Zhang, Han Zhong, Tao Zhang · 2023

Irinotecan was complexed on phosphorylcholine-grafted graphene oxide synthesized via atomic transfer radical polymerization, the biocompatibility and effectiveness of the complex was confirmed and expected to be applied in oncology therapy.

Current trends and hotspots in drug-resistant epilepsy research: Insights from a bibliometric analysis Open

Xiaojun Ni, Han Zhong, Yangxi Liu, Hou‐Wen Lin, Zhi‐Chun Gu · 2022

Background Drug-resistance is a significant clinical issue in persons with epilepsy. In the past few years, many studies have been published investigating the management of drug-resistant epilepsy (DRE); however, no systematic and quantita…

Scars of COVID-19: A bibliometric analysis of post-COVID-19 fibrosis Open

Han Zhong, Yang Zhou, Shuya Mei, Ri Tang, Jinhua Feng , et al. · 2022

Background The coronavirus disease 2019 (COVID-19) becomes a worldwide public health threat. Increasing evidence proves that COVID-19-induced acute injuries could be reversed by a couple of therapies. After that, post-COVID-19 fibrosis (PC…

Antimicrobial Stewardship in Surgery: A Literature Bibliometric Analysis Open

Yangxi Liu, Ya Yang, Ke-Jia Le, Zaili Zhang, Min Cui , et al. · 2022

Background Antimicrobial resistance and the dwindling antibiotic development pipeline have resulted in a looming post-antibiotic era. Research related to antimicrobial stewardship (AMS) has grown rapidly in the past decade, especially in t…

A novel algorithm for diagnosis of invasive pulmonary aspergillosis based on pentraxin 3 gene polymorphisms and its adjusted value among autoimmune diseases patients Open

Yuetian Yu, Chunyan Liu, Cheng Zhu, Han Zhong, Zhichun Gu , et al. · 2022

It was revealed that our new algorithm based on PTX3 gene polymorphisms combined with adjusted BALF GM and BALF PTX3 values performed well in diagnosing IPA.

Ceftazidime-Avibactam as Salvage Treatment for Infections Due to Carbapenem-Resistant Klebsiella pneumoniae in Liver Transplantation Recipients Open

Fang Chen, Han Zhong, Tengjiao Yang, Chuan Shen, Yuxiao Deng , et al. · 2021

CZA shows promising results, even in monotherapy, for the treatment of patients with severe infections due to carbapenem-resistant K. pneumoniae among LT recipients. The emergence of resistance to CZA was not observed.

A bibliometric analysis of infectious diseases in patients with liver transplantation in the last decade Open

Han Zhong, Chunyan Liu, You-Qin Dai, Cheng Zhu, Ke-Jia Le , et al. · 2021

This bibliometric analysis will better understand the research status of infectious complications in LT recipients and forecast future research trends. Priority should be given to identifying risk factors for peritransplantation infections…

Reduction in antimicrobial use associated with a multifaceted antimicrobial stewardship programme in a tertiary teaching hospital in Shanghai: a segmented regression analysis Open

Yangxi Liu, Chen Liang, Ya Yang, Ke-Jia Le, Zaili Zhang , et al. · 2021

This study suggests that MAMS plays an important role in reducing antibiotic use and is not affected by special circumstances such as the COVID-19 pandemic. This novel intervention, consisting of a quality premium and multidisciplinary coo…

Global trends and hotspots in research of carbapenem-resistant Enterobacteriaceae (CRE): a bibliometric analysis from 2010 to 2020 Open

Han Zhong, Fang Chen, Yujie Li, Xianyuan Zhao, Zaili Zhang , et al. · 2021

The bibliometric analysis revealed that development of antibacterial agents, early etiological detection and genome sequencing techniques were the hotspots and would probably direct the future research directions which would also facilitat…

Intra-abdominal infection in acute pancreatitis in eastern China: microbiological features and a prediction model Open

Cheng Zhu, Sheng Zhang, Han Zhong, Zhi‐Chun Gu, Yuening Kang , et al. · 2021

Multidrug-resistant bacteria were quite common in intra-abdominal infection. IAP, APACHE II, CTSI, the severity of pancreatitis, and ICU admission were identified as risk factors and the new nomogram based on these could help clinicians es…

Efficacy and safety of tigecycline for complicated urinary tract infection: a systematic review Open

Yangxi Liu, Ke-Jia Le, Hong-Yao Shi, Zaili Zhang, Min Cui , et al. · 2021

Clinical and microbiological outcomes of tigecycline treatment revealed high rate of successful response. Tigecycline monotherapy may have a role in the treatment of cUTI except that caused by the pathogen K. pneumoniae. Further ran…

Isolation and Characterization of Fengycins Produced by Bacillus amyloliquefaciens JFL21 and Its Broad-Spectrum Antimicrobial Potential Against Multidrug-Resistant Foodborne Pathogens Open

Long-Zhen Lin, Qianwang Zheng, Tao Wei, Ziqian Zhang, Chao-Fan Zhao , et al. · 2020

The continuing emergence and development of pathogenic microorganisms that are resistant to antibiotics constitute an increasing global concern, and the effort in new antimicrobials discovery will remain relevant until a lasting solution i…

Current therapeutic options for coronavirus disease 2019 (COVID-19)—lessons learned from severe acute respiratory syndrome (SARS) and Middle East Respiratory Syndrome (MERS) therapy: a systematic review protocol Open

Zai-Li Zhang, Han Zhong, Yangxi Liu, Ke-Jia Le, Min Cui , et al. · 2020

The protocol of this study has been submitted to the PROSPERO platform (https://www.crd.york.ac.uk/PROSPERO/), and the registration number is CRD42020168639.

Management of Bivalirudin Anticoagulation Therapy for Extracorporeal Membrane Oxygenation in Heparin-Induced Thrombocytopenia: A Case Report and a Systematic Review Open

Han Zhong, Mingli Zhu, Yuetian Yu, Wen Li, Shunpeng Xing , et al. · 2020

PROSPERO, identifier CRD42020160907.

Bloodstream infection caused by Yersinia enterocolitica in a host with ankylosing spondylitis: a case report and literature review Open

Yangxi Liu, Han Zhong, Ke-Jia Le, Min Cui · 2020

The extraintestinal infections caused by Yersinia enterocolitica are very rare, especially in the form of spontaneous bloodstream infection at people without history of blood transfusion. Their clinical symptoms and treatments are still no…

A bibliometric analysis using VOSviewer of publications on COVID-19 Open

Yuetian Yu, Yujie Li, Zhongheng Zhang, Zhi‐Chun Gu, Han Zhong , et al. · 2020

The current growth trends predict a large increase in the number of global publications on COVID-19. China made the most outstanding contribution within this important field. Disease treatment, spike protein and vaccine may be hotspots in …

The Wage Effects of Foreign Acquisition of Chinese Privately-Owned Enterprises Open

Han Zhong · 2020

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