Minlu Zhang
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View article: Effects of improved water, sanitation, handwashing and nutrition on early childhood IgG immune repertoire development against <i>Shigella</i> and enteroinvasive <i>Escherichia coli</i> (EIEC)
Effects of improved water, sanitation, handwashing and nutrition on early childhood IgG immune repertoire development against <i>Shigella</i> and enteroinvasive <i>Escherichia coli</i> (EIEC) Open
We studied effects of a combined water, sanitation, handwashing, and nutritional supplementation (WSH+N) intervention on Shigella/ EIEC IgG immune development among Bangladeshi children enrolled in a cluster randomized trial. We used a bac…
View article: Reconstructing pathogen-specific antibody binding epitopes and age-dependent immune signatures from proteomic-scale peptide libraries
Reconstructing pathogen-specific antibody binding epitopes and age-dependent immune signatures from proteomic-scale peptide libraries Open
Public health interventions involving improved water, sanitation and promotion of hygiene behaviors (WASH) plus nutrition, were implemented in Bangladesh in a large randomized controlled trial to assess impact on childhood enteric infectio…
View article: Assessing the Impact of the Inflation Reduction Act on Medicare Prescription Drug Coverage
Assessing the Impact of the Inflation Reduction Act on Medicare Prescription Drug Coverage Open
s Importance The Inflation Reduction Act (IRA) introduced significant reforms to Medicare Part D in 2025, aiming to reduce medication costs for beneficiaries by eliminating the coverage gap (“donut hole”) with a $2,000 annual out-of-pocket…
View article: Cerebrospinal fluid immune phenotyping reveals distinct immunotypes of myalgic encephalomyelitis/chronic fatigue syndrome
Cerebrospinal fluid immune phenotyping reveals distinct immunotypes of myalgic encephalomyelitis/chronic fatigue syndrome Open
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex heterogeneous multiorgan disease that can have severe impact on individuals' quality of life. Diagnosis of ME/CFS is based on symptom presentation, and a significant …
View article: Population profile and glycemic control following initiation or switch of injectable therapies in Tianjin, China: A real‐world retrospective cohort study of adults with type 2 diabetes
Population profile and glycemic control following initiation or switch of injectable therapies in Tianjin, China: A real‐world retrospective cohort study of adults with type 2 diabetes Open
Aims To evaluate characteristics and glycemic outcomes in individuals with type 2 diabetes using injectable therapies in real‐world clinical practice in Tianjin, China. Materials and methods Data from inpatients and outpatients receiving i…
View article: Treatment Patterns and Glycaemic Control Between 2015 and 2019 in Tianjin, China: A Real-World Study of Adults with Type 2 Diabetes
Treatment Patterns and Glycaemic Control Between 2015 and 2019 in Tianjin, China: A Real-World Study of Adults with Type 2 Diabetes Open
Glycaemic control improved between 2015 and 2019 in people with T2D in Tianjin, China; however, there is an unmet need for more effective glycaemic control.
View article: Profiling antibody epitopes induced by mRNA-1273 vaccination and boosters
Profiling antibody epitopes induced by mRNA-1273 vaccination and boosters Open
Background Characterizing the antibody epitope profiles of messenger RNA (mRNA)-based vaccines against SARS-CoV-2 can aid in elucidating the mechanisms underlying the antibody-mediated immune responses elicited by these vaccines. Methods T…
View article: Distinguishing features of long COVID identified through immune profiling
Distinguishing features of long COVID identified through immune profiling Open
Post-acute infection syndromes may develop after acute viral disease 1 . Infection with SARS-CoV-2 can result in the development of a post-acute infection syndrome known as long COVID. Individuals with long COVID frequently report unremitt…
View article: Profiling antibody epitopes induced by mRNA-1273 vaccination and boosters
Profiling antibody epitopes induced by mRNA-1273 vaccination and boosters Open
Characterizing the antibody epitope profiles of messenger RNA (mRNA)-based vaccines against SARS-CoV-2 can aid in elucidating the mechanisms underlying the antibody-mediated immune responses elicited by these vaccines. This study investiga…
View article: Safety and Effectiveness of Rasburicase in the Control of Hyperuricemia in Pediatric Patients with Non-Hodgkin’s Lymphoma and Acute Leukemia: An Open-Label, Single-Arm, Multi-center, Interventional Study
Safety and Effectiveness of Rasburicase in the Control of Hyperuricemia in Pediatric Patients with Non-Hodgkin’s Lymphoma and Acute Leukemia: An Open-Label, Single-Arm, Multi-center, Interventional Study Open
Rasburicase was well tolerated and effective in controlling hyperuricemia in Chinese pediatric patients with NHL and AL.
View article: Data from Autoantibody Landscape in Patients with Advanced Prostate Cancer
Data from Autoantibody Landscape in Patients with Advanced Prostate Cancer Open
Purpose:Autoantibody responses in cancer are of great interest, as they may be concordant with T-cell responses to cancer antigens or predictive of response to cancer immunotherapies. Thus, we sought to characterize the antibody landscape …
View article: Supplementary Tables S1-S4 from Autoantibody Landscape in Patients with Advanced Prostate Cancer
Supplementary Tables S1-S4 from Autoantibody Landscape in Patients with Advanced Prostate Cancer Open
Supplementary Tables S1-S4
View article: Data from Autoantibody Landscape in Patients with Advanced Prostate Cancer
Data from Autoantibody Landscape in Patients with Advanced Prostate Cancer Open
Purpose:Autoantibody responses in cancer are of great interest, as they may be concordant with T-cell responses to cancer antigens or predictive of response to cancer immunotherapies. Thus, we sought to characterize the antibody landscape …
View article: Supplementary Figures S1-S9 from Autoantibody Landscape in Patients with Advanced Prostate Cancer
Supplementary Figures S1-S9 from Autoantibody Landscape in Patients with Advanced Prostate Cancer Open
Supplementary Figures S1-S9
View article: Supplementary Tables S1-S4 from Autoantibody Landscape in Patients with Advanced Prostate Cancer
Supplementary Tables S1-S4 from Autoantibody Landscape in Patients with Advanced Prostate Cancer Open
Supplementary Tables S1-S4
View article: Supplementary Figures S1-S9 from Autoantibody Landscape in Patients with Advanced Prostate Cancer
Supplementary Figures S1-S9 from Autoantibody Landscape in Patients with Advanced Prostate Cancer Open
Supplementary Figures S1-S9
View article: Correction to: Measuring Self-management Among People with Diabetes Mellitus: A Systematic Review of Patient-Reported Diabetes-Specific Instruments in English and Chinese
Correction to: Measuring Self-management Among People with Diabetes Mellitus: A Systematic Review of Patient-Reported Diabetes-Specific Instruments in English and Chinese Open
View article: Impact of Type 2 Diabetes Duration on the Efficacy and Safety of Add-on Lixisenatide in Asian Individuals Receiving Basal Insulin: A Pooled Analysis
Impact of Type 2 Diabetes Duration on the Efficacy and Safety of Add-on Lixisenatide in Asian Individuals Receiving Basal Insulin: A Pooled Analysis Open
View article: Patient-reported outcome (PRO) instruments for disease severity and quality of life in patients with atopic dermatitis: a systematic review of English and Chinese literature
Patient-reported outcome (PRO) instruments for disease severity and quality of life in patients with atopic dermatitis: a systematic review of English and Chinese literature Open
BACKGROUND: Many patient-reported outcome (PRO) on disease severity quality of life (QOL) have been developed for atopic dermatitis (AD) patients. However, none of them on the reliability and validity of the instruments was sufficient for …
View article: Influence of Baseline HbA1c and Antiplatelet Therapy on 1-Year Vein Graft Outcome
Influence of Baseline HbA1c and Antiplatelet Therapy on 1-Year Vein Graft Outcome Open
In the DACAB trial, lower baseline HbA1c was associated with higher vein graft patency 1 year after CABG. T+A improved 1-year vein graft patency vs A, irrespective of baseline HbA1c.
View article: High-resolution epitope mapping and characterization of SARS-CoV-2 antibodies in large cohorts of subjects with COVID-19
High-resolution epitope mapping and characterization of SARS-CoV-2 antibodies in large cohorts of subjects with COVID-19 Open
View article: Phase Ib study of patients with metastatic castrate-resistant prostate cancer treated with different sequencing regimens of atezolizumab and sipuleucel-T
Phase Ib study of patients with metastatic castrate-resistant prostate cancer treated with different sequencing regimens of atezolizumab and sipuleucel-T Open
Background Combining an immune checkpoint inhibitor with a tumor vaccine may modulate the immune system to leverage complementary mechanisms of action that lead to sustained T-cell activation and a potent prolonged immunotherapeutic respon…
View article: Lixisenatide is effective and safe as add-on treatment to basal insulin in Asian individuals with type 2 diabetes and different body mass indices: a pooled analysis of data from the GetGoal Studies
Lixisenatide is effective and safe as add-on treatment to basal insulin in Asian individuals with type 2 diabetes and different body mass indices: a pooled analysis of data from the GetGoal Studies Open
Introduction This analysis aims to investigate the efficacy and safety of once-daily lixisenatide add-on treatment to basal insulin in Asian individuals with type 2 diabetes, by baseline body mass index (BMI). Research design and methods D…
View article: Comparison of insulin glargine 300 U/mL versus glargine 100 U/mL on glycemic control and hypoglycemic events in East Asian patients with type 2 diabetes: A Patient-level meta-analysis of phase 3 studies
Comparison of insulin glargine 300 U/mL versus glargine 100 U/mL on glycemic control and hypoglycemic events in East Asian patients with type 2 diabetes: A Patient-level meta-analysis of phase 3 studies Open
Gla-300 provides comparable glycemic control to Gla-100 in East Asian patients with broad clinical spectrum of T2DM, with consistently less hypoglycemia at any time of the day and night.
View article: Efficacy of once‐daily glucagon‐like peptide‐1 receptor agonist lixisenatide as an add‐on treatment to basal insulin in Asian and white adults with type 2 diabetes mellitus: An individual‐level pooled analysis of phase III studies
Efficacy of once‐daily glucagon‐like peptide‐1 receptor agonist lixisenatide as an add‐on treatment to basal insulin in Asian and white adults with type 2 diabetes mellitus: An individual‐level pooled analysis of phase III studies Open
Aims/Introduction The prevalence and pathophysiological background of type 2 diabetes mellitus vary across ethnicities, and can affect treatment responses. Adding lixisenatide to basal insulin (BI) in type 2 diabetes mellitus patients has …
View article: High-resolution mapping and characterization of epitopes in COVID-19 patients
High-resolution mapping and characterization of epitopes in COVID-19 patients Open
Fine scale delineation of epitopes recognized by the antibody response to SARS-CoV-2 infection will be critical to understanding disease heterogeneity and informing development of safe and effective vaccines and therapeutics. The Serum Epi…
View article: Autoantibody Landscape in Patients with Advanced Prostate Cancer
Autoantibody Landscape in Patients with Advanced Prostate Cancer Open
Purpose: Autoantibody responses in cancer are of great interest, as they may be concordant with T-cell responses to cancer antigens or predictive of response to cancer immunotherapies. Thus, we sought to characterize the antibody landscape…
View article: Effect of ticagrelor with or without aspirin on vein graft outcome 1 year after on-pump and off-pump coronary artery bypass grafting
Effect of ticagrelor with or without aspirin on vein graft outcome 1 year after on-pump and off-pump coronary artery bypass grafting Open
In the DACAB trial, for patients underwent either on-pump or off-pump CABG, ticagrelor plus aspirin showed consistent benefit for achieving 1-year vein graft patency, with particular benefit being seen in the off-pump.
View article: Autoantibody landscape of advanced prostate cancer
Autoantibody landscape of advanced prostate cancer Open
Although the importance of T-cell immune responses is well appreciated in cancer, autoantibody responses are less well-characterized. Nevertheless, autoantibody responses are of great interest, as they may be concordant with T-cell respons…
View article: Adherence to Dietary Recommendations among Long-Term Breast Cancer Survivors and Cancer Outcome Associations
Adherence to Dietary Recommendations among Long-Term Breast Cancer Survivors and Cancer Outcome Associations Open
Background: Adherence to dietary recommendations has been shown to be associated with reduced mortality in healthy populations. Little is known about the possible benefits of adherence to dietary recommendations among breast cancer survivo…